Search Results - "Santos, Edson L"

Adevonin, a novel synthetic antimicrobial peptide designed from the Adenanthera pavonina trypsin inhibitor (ApTI) sequence by Rodrigues, Mayara S., Oliveira, Caio F. R. de, Almeida, Luís H. O., Neto, Simone M., Boleti, Ana Paula A., Santos, Edson L. dos, Cardoso, Marlon H., Ribeiro, Suzana M., Franco, Octávio L., Rodrigues, Fernando S., Macedo, Alexandre J., Brust, Flávia R., Macedo, Maria Lígia R.

“…The biological activities and the structural arrangement of adevonin, a novel antimicrobial peptide, were investigated. The trypsin inhibitor ApTI, isolated…”
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A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells by Serrano, Fabiana A, Matsuo, Alisson L, Monteforte, Priscila T, Bechara, Alexandre, Smaili, Soraya S, Santana, Débora P, Rodrigues, Tiago, Pereira, Felipe V, Silva, Luis S, Machado, Jr, Joel, Santos, Edson L, Pesquero, João B, Martins, Rafael M, Travassos, Luiz R, Caires, Antonio C F, Rodrigues, Elaine G

“…Systemic therapy for cancer metastatic lesions is difficult and generally renders a poor clinical response. Structural analogs of cisplatin, the most widely…”
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Leaf and Root Extracts from Campomanesia adamantium (Myrtaceae) Promote Apoptotic Death of Leukemic Cells via Activation of Intracellular Calcium and Caspase-3 by Campos, Jaqueline F, Espindola, Priscilla P de Toledo, Torquato, Heron F V, Vital, Wagner D, Justo, Giselle Z, Silva, Denise B, Carollo, Carlos A, de Picoli Souza, Kely, Paredes-Gamero, Edgar J, Dos Santos, Edson L

“…Phytochemical studies are seeking new alternatives to prevent or treat cancer, including different types of leukemias. , commonly known as guavira or…”
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Effect of angiotensin converting enzyme inhibitor enalapril on body weight and composition in young rats by Santos, Edson L., de Picoli Souza, Kely, Guimarães, Paola Bianchi, Reis, Felipe Castellani Gomes, Silva, Sylvia Maria Affonso, Costa-Neto, Claudio M., Luz, Jacqueline, Pesquero, João B.

“…Obesity is considered a worldwide public health problem showing an increased prevalence in developing countries, with urgent need for new and more efficient…”
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Functional rescue of a defective angiotensin II AT1 receptor mutant by the Mas protooncogene by SANTOS, Edson L, REIS, Rosana I, COSTA-NETO, Claudio M, PESQUERO, Joao B, SILVA, Ronaldo G, SHIMUTA, Suma I, PECHER, Christiane, BASCANDS, Jean-Loup, SCHANSTRA, Joost P, OLIVEIRA, Laerte, BADER, Michael, PAIV, Antonio C. M

“…Earlier studies with Mas protooncogene, a member of the G-protein-coupled receptor family, have proposed this gene to code for a functional AngII receptor,…”
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Comparative evaluation of chemical composition and biological activities of tropical fruits consumed in Manaus, central Amazonia, Brazil by Faria, Jéssica V., Valido, Iris H., Paz, Weider H.P., da Silva, Felipe M.A., de Souza, Afonso D.L., Acho, Leonard R.D., Lima, Emerson S., Boleti, Ana Paula A., Marinho, Jane V.N., Salvador, Marcos J., dos Santos, Edson L., Soares, Patrícia K., López-Mesas, Montserrat, Maia, Jair M.F., Koolen, Hector H.F., Bataglion, Giovana A.

“…[Display omitted] •Nine fruits commonly consumed in Manaus (Brazil) were comparatively studied.•Murici and cubiu displayed high reducing and antioxidant…”
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Differential interactions of the antimicrobial peptide, RQ18, with phospholipids and cholesterol modulate its selectivity for microorganism membranes by Almeida, Claudiane V., de Oliveira, Caio F.R., dos Santos, Edson L., dos Santos, Helder F., Júnior, Edson C., Marchetto, Reinaldo, da Cruz, Leticia A., Ferreira, Alda Maria T., Gomes, Valdirene M., Taveira, Gabriel B., Costa, Bruna O., Franco, Octávio L., Cardoso, Marlon H., Macedo, Maria Lígia R.

“…Antimicrobial peptides (AMPs) are molecules with potential application for the treatment of microorganism infections. We, herein, describe the structure,…”
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Reduced-Complexity Polynomials with Memory Applied to the Linearization of Power Amplifiers with Real-Time Discrete Gain Control by Schuartz, Luis, Santos, Edson L., Leite, Bernardo, Mariano, André A., Lima, Eduardo G.

“…In reconfigurable power amplifiers (PAs), the efficiency can be improved by dynamically switching the discrete gain mode according to the input envelope…”
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Spondias purpurea L. Bark Extract Protects against Oxidative Stress and Reduces Hypercholesterolemia in Mice Fed High-Fat Diet by Antunes, Kátia A., Monteiro-Alfredo, Tamaeh, Cunha, Janielle S. M., Espindola, Priscila P. T., Oliveira, Alex S., Ramalho de Oliveira, Caio F., de Carvalho, José Tarcísio G., Domingues, Nelson L. C., Silva, Denise B., Olinto, Silvia C. F., dos Santos, Edson L., de Picoli Souza, Kely

“…Oxidative stress plays a key role in the initiation and progression of metabolic diseases, including obesity. Preventing the accumulation of reactive oxygen…”
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Remela de cachorro (Clavija lancifolia Desf.) fruits from South Amazon: Phenolic composition, biological potential, and aroma analysis by Paz, Weider H.P., de Almeida, Richardson A., Braga, Neila A., da Silva, Felipe M.A., Acho, Leonard D.R., Lima, Emerson S., Boleti, Ana Paula A., dos Santos, Edson L., Angolini, Célio F.F., Bataglion, Giovana A., Koolen, Hector H.F.

“…Remela de cachorro (Clavija lancifolia Desf.) is an Amazonian native fruit consumed specially in the Purus microregion. Because of its rarity, restricted…”
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Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling by Guimarães, Paola B, Alvarenga, Érika C, Siqueira, Paula D, Paredes-Gamero, Edgar J, Sabatini, Regiane A, Morais, Rafael L T, Reis, Rosana I, Santos, Edson L, Teixeira, Luis G D, Casarini, Dulce E, Martin, Renan P, Shimuta, Suma I, Carmona, Adriana K, Nakaie, Clovis R, Jasiulionis, Miriam G, Ferreira, Alice T, Pesquero, Jorge L, Oliveira, Suzana M, Bader, Michael, Costa-Neto, Claudio M, Pesquero, João B

“…Angiotensin (Ang) I-converting enzyme (ACE) is involved in the control of blood pressure by catalyzing the conversion of Ang I into the vasoconstrictor Ang II…”
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ACE Activity Is Modulated by Kinin B2 Receptor by Sabatini, Regiane A, Guimarães, Paola B, Fernandes, Liliam, Reis, Felipe C.G, Bersanetti, Patricia A, Mori, Marcelo A, Navarro, Alberto, Hilzendeger, Aline M, Santos, Edson L, Andrade, Maria C.C, Chagas, Jair R, Pesquero, Jorge L, Casarini, Dulce E, Bader, Michael, Carmona, Adriana K, Pesquero, João B

“…Angiotensin-converting enzyme (ACE) is an ectoprotein able to modulate the activity of a plethora of compounds, among them angiotensin I and bradykinin…”
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Cyclopalladated compounds as chemotherapeutic agents: Antitumor activity against a murine melanoma cell line by Rodrigues, Elaine G., Silva, Luiz S., Fausto, Daniela M., Hayashi, Marina S., Dreher, Simone, Santos, Edson L., Pesquero, João B., Travassos, Luiz R., Caires, Antonio C.F.

“…Palladacycle compounds obtained from N, N‐dimethyl‐1‐phenethylamine (dmpa), phenyl‐2‐pyridinyl‐acetylene and 1‐phenyl‐3‐N, N‐dimethylamine‐propine,…”
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Biological and conformational evaluation of angiotensin II lactam bridge containing analogues by Oliveira, Vani X., Fázio, Marcos A., Silva, Adriana F., Campana, Patrícia T., Pesquero, João B., Santos, Edson L., Costa-Neto, Cláudio M., Miranda, Antonio

“…Angiotensin II (AII) is the active octapeptide product of the renin enzymatic cascade, which is responsible for sustaining blood pressure. In an attempt to…”
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Early pharmacological inhibition of angiotensin-I converting enzyme activity induces obesity in adulthood by de Picoli Souza, Kely, da Silva, Elton D, Batista, Elice C, Reis, Felipe C G, Silva, Sylvia M A, Castro, Charlles H M, Luz, Jaqueline, Pesquero, Jorge L, Dos Santos, Edson L, Pesquero, João B

“…We have investigated early programming of body mass in order to understand the multifactorial etiology of obesity. Considering that the renin-angiotensin…”
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Mutagenesis of the AT1 receptor reveals different binding modes of angiotensin II and [Sar1]-angiotensin II by SANTOS, Edson L, PESQUERO, Joao B, OLIVEIRA, Laerte, PAIVA, Antonio C. M, COSTA-NETO, Claudio M

“…Homology modeling of the structure of the AT1 receptor, based on the high resolution rhodopsin crystal structure, indicated that it is unlikely that the…”
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Participation of transmembrane proline 82 in angiotensin II AT1 receptor signal transduction by REIS, Rosana I, SANTOS, Edson L, PESQUERO, Joao B, OLIVEIRA, Laerte, SCHANSTRA, Joost P, BASCANDS, Jean-Loup, PECHER, Christiane, PAIVA, Antonio C. M, COSTA-NETO, Claudio M

“…Most of the classical physiological effects of the octapeptide angiotensin II (AngII) are produced by activating the AT1 receptor which belongs to the…”
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Functional assessment of angiotensin II and bradykinin analogues containing the paramagnetic amino acid TOAC by Santos, Edson L., Souza, Kely de Picoli, Sabatini, Regiane A., Martin, Renan P., Fernandes, Liliam, Nardi, Daniela T., Malavolta, Luciana, Shimuta, Suma I., Nakaie, Clóvis R., Pesquero, João B.

“…This study characterized pharmacologically the functional responses to agonists angiotensin II (AngII) and bradykinin (BK) derivatives containing the TOAC…”
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Essential role of TM V and VI for binding the C-terminal sequences of Des-Arg-kinins by Santos, Edson L., de Picoli Souza, Kely, Cibrián-Uhalte, Elena, Oliveira, Suzana M., Bader, Michael, Costa-Neto, Claudio M., Oliveira, Laerte, Pesquero, João B.

“…In the kallikrein–kinin and renin–angiotensin systems the main receptors, B1 and B2 (kinin receptors) and AT1 and AT2 (angiotensin receptors) respectively, are…”
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Anti-inflammatory and antioxidant properties of Bertholletia excelsa(H.B.K) bark extract by Silva, Marcia J A, Boleti, Ana Paula A, Acho, Leonard D. R., Campos, Jaqueline F, Neto, Jose P.M., Guimaraes, Anderson, Silva, Felipe M.A., Koolen, Hector H.F., Santos, Edson L., Lima, Emerson S.

“…Bertholletia excelsais native to the Amazon Rainforest and is popularly known as the Brazil nut. It has socioeconomic importance due its nuts being a great…”
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