Primary photosensitization caused by ingestion of Froelichia humboldtiana by dairy goats

This study aimed to describe the first report of an outbreak of primary photosensitization in dairy goats caused by Froelichia humboldtiana. The disease occurred from March to May 2014, in a mixed flock of 15 Saanen, Alpine, and crossbred lactating goats. The entire flock was affected; however, the...

Full description

Saved in:

Bibliographic Details
Published in:	Toxicon (Oxford) Vol. 125; pp. 65 - 69
Main Authors:	Santos, Danielle S., Silva, Caio C.B., Araújo, Valber O., de Fátima Souza, Maria, Lacerda-Lucena, Patrícia B., Simões, Sara V.D., Riet-Correa, Franklin, Lucena, Ricardo B.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-01-2017
Subjects:	Amaranthaceae - poisoning Animals Aspartate Aminotransferases - blood Bilirubin - blood Disease Outbreaks - veterinary Female Goat disease Goat Diseases - chemically induced Goats Lactation - drug effects Low milk production Photodermatitis Photosensitivity Disorders - chemically induced Photosensitivity Disorders - veterinary Skin necrosis Skin necrosis Low milk production Photodermatitis Goat disease
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	This study aimed to describe the first report of an outbreak of primary photosensitization in dairy goats caused by Froelichia humboldtiana. The disease occurred from March to May 2014, in a mixed flock of 15 Saanen, Alpine, and crossbred lactating goats. The entire flock was affected; however, the Saanen and cross-bred goats developed more severe lesions, and their milk production decreased by as much as 75%. Lesions were progressive and consisted of skin hyperemia, edema, and necrosis, especially in depigmented areas. An experimental study with two goats resulted in photodermatitis, similar to that observed in the natural cases, 10–14 days after the beginning of plant ingestion. Serum activities of aspartate aminotransferase (AST) and -glutamyltransferase (GGT) and, direct, indirect, and total bilirubin serum concentrations were within the normal ranges. In conclusion, F. humboldtiana causes primary photosensitization in goats with a negative impact on milk production. •Froelichia humboldtiana is a common plant in the Brazilian semiarid region.•Photodermatitis in goats is associated with the ingestion of this plant.•To induce the disease experimental, goats were placed in a pasture composed by F. humboldtiana.•Experimentally F. humboldtiana caused photosensitization in goats.•F. humboldtiana is a cause of primary photosensitization and low milk production in dairy goats.
ISSN:	0041-0101 1879-3150
DOI:	10.1016/j.toxicon.2016.11.258