Search Results - "Santos, Celio XC"

Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signalling Loop by Viswambharan, Hema, Yuldasheva, Nadira, Sengupta, Anshuman, Imrie, Helen, Gage, Matthew, Haywood, Natalie, Walker, Andrew MN, Skromna, Anna, Makova, Natallia, Galloway, Stacey, Shah, Pooja, Sukumar, Piruthivi, Porter, Karen E, Grant, Peter J, Shah, Ajay M, Santos, Celio XC, Li, Jing, Beech, David J, Wheatcroft, Stephen B, Cubbon, Richard M, Kearney, Mark T

“…RATIONALE:In the endothelium, insulin stimulates endothelial nitric oxide synthase (eNOS) to generate the anti-atherosclerotic signalling radical NO. Insulin…”
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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling by Randzavola, Lyra O, Mortimer, Paige M, Garside, Emma, Dufficy, Elizabeth R, Schejtman, Andrea, Roumelioti, Georgia, Yu, Lu, Pardo, Mercedes, Spirohn, Kerstin, Tolley, Charlotte, Brandt, Cordelia, Harcourt, Katherine, Nichols, Esme, Nahorski, Mike, Woods, Geoff, Williamson, James C, Suresh, Shreehari, Sowerby, John M, Matsumoto, Misaki, Santos, Celio X C, Kiar, Cher Shen, Mukhopadhyay, Subhankar, Rae, William M, Dougan, Gordon J, Grainger, John, Lehner, Paul J, Calderwood, Michael A, Choudhary, Jyoti, Clare, Simon, Speak, Anneliese, Santilli, Giorgia, Bateman, Alex, Smith, Kenneth G C, Magnani, Francesca, Thomas, David C

“…EROS (essential for reactive oxygen species) protein is indispensable for expression of gp91 , the catalytic core of the phagocyte NADPH oxidase. EROS…”
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Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration by Magadum, Ajit, Singh, Neha, Kurian, Ann Anu, Munir, Irsa, Mehmood, Talha, Brown, Kemar, Sharkar, Mohammad Tofael Kabir, Chepurko, Elena, Sassi, Yassine, Oh, Jae Gyun, Lee, Philyoung, Santos, Celio X.C., Gaziel-Sovran, Avital, Zhang, Guoan, Cai, Chen-Leng, Kho, Changwon, Mayr, Manuel, Shah, Ajay M., Hajjar, Roger J., Zangi, Lior

“…BACKGROUND:The adult mammalian heart has limited regenerative capacity, mostly attributable to postnatal cardiomyocyte cell cycle arrest. In the last 2…”
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Nox4 regulates InsP3 receptor‐dependent Ca2+ release into mitochondria to promote cell survival by Beretta, Matteo, Santos, Celio XC, Molenaar, Chris, Hafstad, Anne D, Miller, Chris CJ, Revazian, Aram, Betteridge, Kai, Schröder, Katrin, Streckfuß‐Bömeke, Katrin, Doroshow, James H, Fleck, Roland A, Su, Tsung‐Ping, Belousov, Vsevolod V, Parsons, Maddy, Shah, Ajay M

“…Cells subjected to environmental stresses undergo regulated cell death (RCD) when homeostatic programs fail to maintain viability. A major mechanism of RCD is…”
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Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2 by Nabeebaccus, Adam A, Verma, Sharwari, Zoccarato, Anna, Emanuelli, Giulia, Santos, Celio XC, Streckfuss-Bömeke, Katrin, Shah, Ajay M.

“…In response to cardiac injury, increased activity of the hexosamine biosynthesis pathway (HBP) is linked with cytoprotective as well as adverse effects…”
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Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling by Santos, Celio XC, Hafstad, Anne D, Beretta, Matteo, Zhang, Min, Molenaar, Chris, Kopec, Jola, Fotinou, Dina, Murray, Thomas V, Cobb, Andrew M, Martin, Daniel, Zeh Silva, Maira, Anilkumar, Narayana, Schröder, Katrin, Shanahan, Catherine M, Brewer, Alison C, Brandes, Ralf P, Blanc, Eric, Parsons, Maddy, Belousov, Vsevelod, Cammack, Richard, Hider, Robert C, Steiner, Roberto A, Shah, Ajay M

“…Phosphorylation of translation initiation factor 2α (eIF2α) attenuates global protein synthesis but enhances translation of activating transcription factor 4…”
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Nox4 regulates InsP 3 receptor-dependent Ca 2+ release into mitochondria to promote cell survival by Beretta, Matteo, Santos, Celio Xc, Molenaar, Chris, Hafstad, Anne D, Miller, Chris Cj, Revazian, Aram, Betteridge, Kai, Schröder, Katrin, Streckfuß-Bömeke, Katrin, Doroshow, James H, Fleck, Roland A, Su, Tsung-Ping, Belousov, Vsevolod V, Parsons, Maddy, Shah, Ajay M

“…Cells subjected to environmental stresses undergo regulated cell death (RCD) when homeostatic programs fail to maintain viability. A major mechanism of RCD is…”
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Protein disulfide isomerase redox-dependent association with p47phox: evidence for an organizer role in leukocyte NADPH oxidase activation by de A. Paes, Antonio Marcus, Veríssimo-Filho, Sidney, Guimarães, Luciana Lopes, Silva, Ana Carolina B, Takiuti, Júlia T, Santos, Célio X C, Janiszewski, Mariano, Laurindo, Francisco R M, Lopes, Lucia R

“…Leukocyte NADPH oxidase activity is regulated by associated protein disulfide isomerase via redox mechanisms involving p47phox. Mechanisms of leukocyte NADPH…”
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Regulation of NAD(P)H Oxidase by Associated Protein Disulfide Isomerase in Vascular Smooth Muscle Cells by Janiszewski, Mariano, Lopes, Lucia Rossetti, Carmo, Alípio O., Pedro, Marcelo A., Brandes, Ralf P., Santos, Célio X.C., Laurindo, Francisco R.M.

“…NAD(P)H oxidase, the main source of reactive oxygen species in vascular cells, is known to be regulated by redox processes and thiols. However, the nature of…”
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Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation by Nabeebaccus, Adam A, Zoccarato, Anna, Hafstad, Anne D, Santos, Celio Xc, Aasum, Ellen, Brewer, Alison C, Zhang, Min, Beretta, Matteo, Yin, Xiaoke, West, James A, Schröder, Katrin, Griffin, Julian L, Eykyn, Thomas R, Abel, E Dale, Mayr, Manuel, Shah, Ajay M

“…Cardiac hypertrophic remodeling during chronic hemodynamic stress is associated with a switch in preferred energy substrate from fatty acids to glucose,…”
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Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2[alpha]-mediated stress signaling by Santos, Celio XC, Hafstad, Anne D, Beretta, Matteo, Zhang, Min, Molenaar, Chris, Kopec, Jola, Fotinou, Dina, Murray, Thomas V, Cobb, Andrew M, Martin, Daniel, Zeh Silva, Maira, Anilkumar, Narayana, Schroder, Katrin, Shanahan, Catherine M, Brewer, Alison C, Brandes, Ralf P, Blanc, Eric, Parsons, Maddy, Belousov, Vsevelod, Cammack, Richard, Hider, Robert C, Steiner, Roberto A, Shah, Ajay M

“…Phosphorylation of translation initiation factor 2[alpha] (eIF2[alpha]) attenuates global protein synthesis but enhances translation of activating…”
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Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF 2α‐mediated stress signaling by Santos, Celio XC, Hafstad, Anne D, Beretta, Matteo, Zhang, Min, Molenaar, Chris, Kopec, Jola, Fotinou, Dina, Murray, Thomas V, Cobb, Andrew M, Martin, Daniel, Zeh Silva, Maira, Anilkumar, Narayana, Schröder, Katrin, Shanahan, Catherine M, Brewer, Alison C, Brandes, Ralf P, Blanc, Eric, Parsons, Maddy, Belousov, Vsevelod, Cammack, Richard, Hider, Robert C, Steiner, Roberto A, Shah, Ajay M

“…Abstract Phosphorylation of translation initiation factor 2α ( eIF 2α) attenuates global protein synthesis but enhances translation of activating transcription…”
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