Search Results - "Santos, Bruno P. O."
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S. mansoni SmKI-1 Kunitz-domain: Leucine point mutation at P1 site generates enhanced neutrophil elastase inhibitory activity
Published in PLoS neglected tropical diseases (19-01-2021)“…The Schistosoma mansoni SmKI-1 protein is composed of two domains: a Kunitz-type serine protease inhibitor motif (KD) and a C-terminus domain with no…”
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Journal Article -
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Recombinant Bacillus Calmette-Guérin Expressing SARS-CoV-2 Chimeric Protein Protects K18-hACE2 Mice against Viral Challenge
Published in The Journal of immunology (1950) (15-06-2023)“…COVID-19 has accounted for more than 6 million deaths worldwide. Bacillus Calmette-Guérin (BCG), the existing tuberculosis vaccine, is known to induce…”
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Journal Article -
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Serine protease inhibitors containing a Kunitz domain: their role in modulation of host inflammatory responses and parasite survival
Published in Microbes and infection (01-10-2018)“…Proteins containing a Kunitz domain have the typical serine protease inhibition function ranging from sea anemone to man. Protease inhibitors play major roles…”
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Modulation of Macrophage Responses by CMX, a Fusion Protein Composed of Ag85c, MPT51, and HspX from Mycobacterium tuberculosis
Published in Frontiers in microbiology (12-04-2017)“…Bacillus Calmette-Guérin (BCG) is a vaccine used to prevent tuberculosis (TB). Due to the poor protection conferred by BCG in adults, new, more effective…”
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Journal Article -
5
Recombinant BCG expressing SARS-CoV-2 chimeric protein protects K18-hACE2 mice against viral challenge
Published in The Journal of immunology (1950) (15-06-2023)“…COVID-19 has accounted for more than six million deaths worldwide. Bacillus Calmette-Guérin (BCG), the existing tuberculosis vaccine, is known to induce…”
Get full text
Journal Article