Search Results - "Santos, Ana L"
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1
The value of antimicrobial peptides in the age of resistance
Published in The Lancet infectious diseases (01-09-2020)“…Accelerating growth and global expansion of antimicrobial resistance has deepened the need for discovery of novel antimicrobial agents. Antimicrobial peptides…”
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2
Towards the Hydrogen Economy—A Review of the Parameters That Influence the Efficiency of Alkaline Water Electrolyzers
Published in Energies (Basel) (01-06-2021)“…Environmental issues make the quest for better and cleaner energy sources a priority. Worldwide, researchers and companies are continuously working on this…”
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3
Optimization of Printing Parameters for Digital Light Processing 3D Printing of Hollow Microneedle Arrays
Published in Pharmaceutics (02-11-2021)“…3D printing is an emerging technology aiming towards personalized drug delivery, among many other applications. Microneedles (MN) are a viable method for…”
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4
Damage dynamics and the role of chance in the timing of E. coli cell death
Published in Nature communications (18-04-2023)“…Genetically identical cells in the same stressful condition die at different times. The origin of this stochasticity is unclear; it may arise from different…”
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Sequence-based prediction of the intrinsic solubility of peptides containing non-natural amino acids
Published in Nature communications (17-11-2023)“…Non-natural amino acids are increasingly used as building blocks in the development of peptide-based drugs as they expand the available chemical space to…”
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Design and Application of a Low pH Upflow Biofilm Sulfidogenic Bioreactor for Recovering Transition Metals From Synthetic Waste Water at a Brazilian Copper Mine
Published in Frontiers in microbiology (30-08-2018)“…A sulfidogenic bioreactor, operated at low pH (4-5), was set up and used to remove transition metals (copper, nickel, cobalt, and zinc) from a synthetic mine…”
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7
Thermo-Responsive self-assembly of a dual glucagon-like peptide and glucagon receptor agonist
Published in International journal of pharmaceutics (15-07-2021)“…The discovery of functional amyloids has inspired tunable self-assembled materials composed of amyloid-like systems. Nanofibrils formed by the human peptide…”
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Developing Culturally Competent Foreign Language Neuropsychological Assessments: Portuguese-Speaking Brazilians Living in the United States
Published in Archives of clinical neuropsychology (26-04-2023)“…Abstract Objective As the third largest immigrant population in Houston, Texas, Brazilians represent a large bloc of the community in need of culturally and…”
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9
Evaluation of new compositions of 10% hydrogen peroxide‐based bleaching agents containing trimetaphosphate and fluoride on enamel demineralization
Published in European journal of oral sciences (01-10-2020)“…This study evaluated the effect on enamel demineralization of 10% hydrogen peroxide (H2O2) gels containing different concentrations of sodium trimetaphosphate…”
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10
Control of Peptide Aggregation and Fibrillation by Physical PEGylation
Published in Biomacromolecules (08-10-2018)“…Peptide therapeutics have the potential to self-associate, leading to aggregation and fibrillation. Noncovalent PEGylation offers a strategy to improve their…”
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Obesity and aging: Molecular mechanisms and therapeutic approaches
Published in Ageing research reviews (01-05-2021)“…•Obesity is a major public health problem.•The metabolic dysregulation associated with obesity is remarkably similar to that observed in normal…”
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12
Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly
Published in Nature communications (18-10-2017)“…The use of peptides as therapeutic agents is undergoing a renaissance with the expectation of new drugs with enhanced levels of efficacy and safety. Their…”
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13
Hepatocellular carcinoma treatment with Sorafenib: A remarkable case of eight-years remission without significant toxicity
Published in Annals of hepatology (01-03-2021)Get full text
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14
Effects of UV Radiation on the Lipids and Proteins of Bacteria Studied by Mid-Infrared Spectroscopy
Published in Environmental science & technology (18-06-2013)“…Knowledge of the molecular effects of UV radiation (UVR) on bacteria can contribute to a better understanding of the environmental consequences of enhanced UV…”
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15
Self-assembled GLP-1/glucagon peptide nanofibrils prolong inhibition of food intake
Published in Frontiers in endocrinology (Lausanne) (24-07-2023)“…Oxyntomodulin (Oxm) hormone peptide has a number of beneficial effects on nutrition and metabolism including increased energy expenditure and reduced body…”
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16
Visible‐Light‐Activated Molecular Machines Kill Fungi by Necrosis Following Mitochondrial Dysfunction and Calcium Overload
Published in Advanced science (01-04-2023)“…Invasive fungal infections are a growing public health threat. As fungi become increasingly resistant to existing drugs, new antifungals are urgently needed…”
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17
Biofilm formation by Staphylococcus pseudintermedius on titanium implants
Published in Biofouling (Chur, Switzerland) (2024)“…Osteomyelitis often involves Staphylococcus spp. as the isolated genus in domestic animal cases. Implant-related infections, frequently associated with…”
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Lipids in the cell: organisation regulates function
Published in Cellular and molecular life sciences : CMLS (01-06-2018)“…Lipids are fundamental building blocks of all cells and play important roles in the pathogenesis of different diseases, including inflammation, autoimmune…”
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Hemithioindigo‐Based Visible Light‐Activated Molecular Machines Kill Bacteria by Oxidative Damage
Published in Advanced science (01-10-2022)“…Antibiotic resistance is a growing health threat. There is an urgent and critical need to develop new antimicrobial modalities and therapies. Here, a set of…”
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20
Contribution of reactive oxygen species to UV-B-induced damage in bacteria
Published in Journal of photochemistry and photobiology. B, Biology (05-12-2012)“…► ROS involved in UV-B damage in bacteria were identified using specific scavengers. ► Singlet oxygen participates in lipid peroxidation and inactivation by…”
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