Search Results - "Santoriello, Marisabella"
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Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors
Published in Scientific reports (24-03-2020)“…Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by releasing cytokines that stimulate the differentiation of myogenic stem…”
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5,6-Dihydroxypyrimidine Scaffold to Target HIV‑1 Nucleocapsid Protein
Published in ACS medicinal chemistry letters (14-05-2020)“…The HIV-1 nucleocapsid (NC) protein is a small basic DNA and RNA binding protein that is absolutely necessary for viral replication and thus represents a…”
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Antifungal activity of azole compounds CPA18 and CPA109 against azole-susceptible and -resistant strains of Candida albicans
Published in Journal of antimicrobial chemotherapy (01-05-2013)“…In this study we investigated the in vitro fungistatic and fungicidal activities of CPA18 and CPA109, two azole compounds with original structural features,…”
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Modulation of Cell Differentiation, Proliferation, and Tumor Growth by Dihydrobenzyloxopyrimidine Non-Nucleoside Reverse Transcriptase Inhibitors
Published in Journal of medicinal chemistry (25-08-2011)“…A series of 5-alkyl-2-(alkylthio)-6-(1-(2,6-difluorophenyl)propyl)-3,4-dihydropyrimidin-4(3H)-one derivatives (3a–h) belonging to the F 2-DABOs class of…”
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5
CYP19 (aromatase): Exploring the scaffold flexibility for novel selective inhibitors
Published in Bioorganic & medicinal chemistry (15-09-2008)“…Several derivatives out of a series of antifungal agents exhibited a good inhibitory potency against aromatase as well as a fairly good selectivity toward…”
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A practical, green, and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction
Published in Tetrahedron letters (21-01-2008)“…A convenient method for double Michael additions to quinone systems catalyzed by Al 2O 3, is reported. The advantages of this method include the use of a cheap…”
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Unprecedented synthesis of a novel amino quinone ring system via oxidative decarboxylation of quinone-based alpha,alpha-amino esters
Published in Organic & biomolecular chemistry (01-01-2010)“…An unusual and efficient method for the synthesis of new quinone-based amine and its derivatives from the corresponding alpha,alpha-amino ester is described…”
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A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems
Published in Tetrahedron letters (09-12-2009)“…An inexpensive and regioselective approach to dihydrothieno[3,2- g]quinoline-4,9-dione is reported. A combination of a mild version of Skraup reaction with a…”
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