Search Results - "Santo Neto, Humberto"

P2Y2 purinergic receptors are highly expressed in cardiac and diaphragm muscles of mdx mice, and their expression is decreased by suramin by De Oliveira Moreira, Drielen, Santo Neto, Humberto, Marques, Maria Julia

“…ABSTRACT Introduction: In Duchenne muscular dystrophy (DMD) and in the mdx mouse model of DMD, the lack of dystrophin leads to increased calcium influx and…”
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Checking the shape and lobation of the right atrial appendage in view of their clinical relevance by Rissi, Renato, Marques, Maria Julia, Neto, Humberto Santo

“…Clinically, anatomy of the appendage of the atrium is associated with atrial fibrillation, with the shape and lobation of the appendage having been used to…”
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Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice hearts at later stages of dystrophy by Mauricio, Adriana Fogagnolo, Pereira, Juliano Alves, Neto, Humberto Santo, Marques, Maria Julia

“…Abstract Objective In the present study, we investigated whether omega-3 would be effective against dystrophic cardiomyopathy, at later stages (13 and 17…”
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Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice by Fogagnolo Mauricio, Adriana, Minatel, Elaine, Santo Neto, Humberto, Marques, Maria Julia

“…Summary Background & aims In Duchenne muscular dystrophy (DMD) and in the mdx mouse model of DMD, the lack of dystrophin leads to muscle degeneration and…”
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Cardiac and skeletal muscle changes associated with rosuvastatin therapy in dystrophic mdx mice by Finkler, Júlia M.G., Carvalho, Samara C., Santo Neto, Humberto, Marques, Maria J.

“…Statins are prescribed to prevent and treat atherosclerotic cardiovascular and metabolic diseases but have controversial effects on skeletal muscles. While…”
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Ascorbic acid protects the diaphragm muscle against myonecrosis in mdx mice by Tonon, Erika, M.Sc, Ferretti, Renato, M.Sc, Shiratori, Jean Hideki, B.Sc, Santo Neto, Humberto, Ph.D, Marques, Maria Julia, Ph.D, Minatel, Elaine, Ph.D

“…Abstract Objective Oxidative stress contributes to myonecrosis in the dystrophin-deficient fibers of mdx mice and in Duchenne’s muscular dystrophy. We examined…”
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Understanding the beneficial effects of doxycycline on the dystrophic phenotype of the mdx mouse by Pereira, Juliano Alves, Matsumura, Cintia Yuri, Minatel, Elaine, Marques, Maria Julia, Santo Neto, Humberto

“…ABSTRACT Introduction: The purpose of this study was to better understand the beneficial effects of doxycycline on the dystrophic muscles of the mdx mouse…”
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Expression of calcium‐buffering proteins in rat intrinsic laryngeal muscles by Ferretti, Renato, Marques, Maria Julia, Khurana, Tejvir S., Santo Neto, Humberto

“…Intrinsic laryngeal muscles (ILM) are highly specialized muscles involved in phonation and airway protection, with unique properties that allow them to perform…”
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Intrinsic laryngeal muscles are spared from myonecrosis in the mdx mouse model of Duchenne muscular dystrophy by Marques, Maria Julia, Ferretti, Renato, Vomero, Viviane Urbini, Minatel, Elaine, Neto, Humberto Santo

“…Intrinsic laryngeal muscles share many anatomical and physiological properties with extraocular muscles, which are unaffected in both Duchenne muscular…”
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Diltiazem and verapamil protect dystrophin-deficient muscle fibers of MDX mice from degeneration: A potential role in calcium buffering and sarcolemmal stability by Matsumura, Cintia Yuri, Pertille, Adriana, Albuquerque, Tereza C.P., Santo Neto, Humberto, Marques, Maria Julia

“…The lack of dystrophin in mdx mice and in Duchenne muscular dystrophy causes sarcolemmal breakdown and increased calcium influx followed by myonecrosis. We…”
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Prevention of muscle fibrosis and myonecrosis in mdx mice by suramin, a TGF-β1 blocker by Taniguti, Ana Paula Tiemi, Pertille, Adriana, Matsumura, Cíntia Yuri, Neto, Humberto Santo, Marques, Maria Julia

“…Fibrosis is a pathological feature observed in patients with Duchenne muscular dystrophy (DMD) and in mdx mice, the experimental model of DMD. We evaluated the…”
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Acetylcholine receptor distribution and synapse elimination at the developing neuromuscular junction of mdx mice by Minatel, Elaine, Neto, Humberto Santo, Marques, Maria Julia

“…The pattern of innervation of the vertebrate neuromuscular junction is established during early development, when junctions go from multiple to single…”
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Identification of plasma interleukins as biomarkers for deflazacort and omega-3 based Duchenne muscular dystrophy therapy by de Carvalho, Samara Camaçari, Matsumura, Cintia Yuri, Santo Neto, Humberto, Marques, Maria Julia

“…•Plasma biomarkers are needed to follow dystrophy progression.•TNF-α, TGF-β, IL-6, -10, -13 and INF-γ proven to be suitable biomarkers.•Deflazacort and omega-3…”
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Fish oil attenuated dystrophic muscle markers of inflammation via FFA1 and FFA4 in the mdx mouse model of DMD by Maciel Junior, Marcos, Carvalho, Samara, Saenz Suarez, Paula Andrea, Santo Neto, Humberto, Marques, Maria Julia

“…In the present study we investigated the involvement of free fatty acid (FFA) receptors in the anti‐inflammatory role of eicosapentaenoic acid (EPA) and…”
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Stretch-activated calcium channel protein TRPC1 is correlated with the different degrees of the dystrophic phenotype in mdx mice by Matsumura, Cíntia Yuri, Taniguti, Ana Paula Tiemi, Pertille, Adriana, Santo Neto, Humberto, Marques, Maria Julia

“…In Duchenne muscular dystrophy (DMD) and in the mdx mouse model of DMD, the lack of dystrophin is related to enhanced calcium influx and muscle degeneration…”
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N-Acetylcysteine treatment reduces TNF-α levels and myonecrosis in diaphragm muscle of mdx mice by de Senzi Moraes Pinto, Rafael, Ferretti, Renato, Moraes, Luis Henrique Rapucci, Neto, Humberto Santo, Marques, Maria Julia, Minatel, Elaine

“…Summary Background & aims Duchenne muscular dystrophy (DMD) is a genetic muscle disease caused by the absence of dystrophin. An established animal model of DMD…”
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Correlation of crista terminalis thickness and right atrial appendage lobation: Implications on arrhythmias and atrial thrombosis by Rissi, Renato, MSc, Marques, Maria Julia, PhD, Neto, Humberto Santo, PhD

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Diaphragm degeneration and cardiac structure in mdx mouse: potential clinical implications for Duchenne muscular dystrophy by Barbin, Isabel Cristina Chagas, Pereira, Juliano Alves, Bersan Rovere, Matheus, Oliveira Moreira, Drielen, Marques, Maria Julia, Santo Neto, Humberto

“…We examined the effects of exercise on diaphragm degeneration and cardiomyopathy in dystrophin‐deficient mdx mice. Mdx mice (11 months of age) were exercised…”
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Eicosapentaenoic acid decreases TNF-α and protects dystrophic muscles of mdx mice from degeneration by Machado, Rafael Ventura, Mauricio, Adriana Fogagnolo, Taniguti, Ana Paula Tiemi, Ferretti, Renato, Neto, Humberto Santo, Marques, Maria Julia

“…Abstract In dystrophin-deficient fibers of mdx mice and in Duchenne muscular dystrophy, inflammation and increased production of tumor necrosis factor alpha…”
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EPA protects against muscle damage in the mdx mouse model of Duchenne muscular dystrophy by promoting a shift from the M1 to M2 macrophage phenotype by de Carvalho, Samara Camaçari, Apolinário, Leticia Montanholi, Matheus, Selma Maria Michelin, Santo Neto, Humberto, Marques, Maria Julia

“…Abstract In dystrophic mdx mice and in Duchenne muscular dystrophy, inflammation contributes to myonecrosis. Previously, we demonstrated that eicosapentaenoic…”
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