Search Results - "Santini, Stefano A."

Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM by SANTINI, S. A, MARRA, G, GIARDINA, B, COTRONEO, P, MORDENTE, A, MARTORANA, G. E, MANTO, A, GHIRLANDA, G

“…Oxidative stress is postulated to be increased in patients with IDDM. Accumulating evidence suggests that oxidative cell injury caused by free radicals…”
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Oxidative stress, nitric oxide, and diabetes by Pitocco, Dario, Zaccardi, Francesco, Di Stasio, Enrico, Romitelli, Federica, Santini, Stefano A, Zuppi, Cecilia, Ghirlanda, Giovanni

“…In the recent decades, oxidative stress has become focus of interest in most biomedical disciplines and many types of clinical research. Increasing evidence…”
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Potential therapeutic effect of antioxidants in experimental diabetic retina: a comparison between chronic taurine and vitamin E plus selenium supplementations by Di Leo, Mauro A S, Ghirlanda, Giovanni, Gentiloni Silveri, Nicolo, Giardina, Bruno, Franconi, Flavia, Santini, Stefano A

“…Although good glycaemic control can delay the development and progression of diabetic retinopathy, new therapies are needed to obtain a better control of this…”
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Role of cytochrome P4502D6 functional polymorphisms in the efficacy of donepezil in patients with Alzheimerʼs disease by Seripa, Davide, Bizzarro, Alessandra, Pilotto, Andrea, DʼOnofrio, Grazia, Vecchione, Gennaro, Gallo, Antonietta P, Cascavilla, Leandro, Paris, Francesco, Grandone, Elvira, Mecocci, Patrizia, Santini, Stefano A, Masullo, Carlo, Pilotto, Alberto

“…OBJECTIVECytochrome P450 (CYP) 2D6 enzyme is the major responsible for the metabolism of donepezil, an inhibitor of acetyl cholinesterase currently used for…”
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Atorvastatin Treatment Does Not Affect Gonadal and Adrenal Hormones in Type 2 Diabetes Patients with Mild to Moderate Hypercholesterolemia by Santini, Stefano A., Carrozza, Cinzia, Lulli, Paola, Zuppi, Cecilia, Tonolo, Gian Carlo, Musumeci, Salvatore

“…Atorvastatin, a second generation synthetic 3-hydroxy 3-methylglutaryl-coenzyme-A (HMG-CoA) reductase inhibitor used in the treatment of hypercholesterolemia,…”
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Vitamin D status in primary hyperparathyroidism: effect of genetic background by Battista, Claudia, Guarnieri, Vito, Carnevale, Vincenzo, Baorda, Filomena, Pileri, Mauro, Garrubba, Maria, Salcuni, Antonio S., Chiodini, Iacopo, Minisola, Salvatore, Romagnoli, Elisabetta, Eller-Vainicher, Cristina, Santini, Stefano A., Parisi, Salvatore, Frusciante, Vincenzo, Fontana, Andrea, Copetti, Massimiliano, Hendy, Geoffrey N., Scillitani, Alfredo, Cole, David E. C.

“…Primary hyperparathyroidism (PHPT) is associated with hypovitaminosis D as assessed by serum total 25-hydroxyvitamin D (TotalD) levels. The aim of this study…”
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Role of CYP2D6 Polymorphisms in the Outcome of Postoperative Pain Treatment by Seripa, Davide, Latina, Paola, Fontana, Andrea, Gravina, Carolina, Lattanzi, Monia, Savino, Maria, Gallo, Antonietta P., Melchionda, Giuseppe, Santini, Stefano A., Margaglione, Maurizio, Copetti, Massimiliano, di Mauro, Lazzaro, Panza, Francesco, Greco, Antonio, Pilotto, Alberto

“…Objective To investigate the role of CYP2D6 phenotype in the outcome of postoperative (PO) pain (POP) treatment. Design Longitudinal cohort study. Open‐label…”
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Early increase of oxidative stress and reduced antioxidant defenses in patients with uncomplicated type 1 diabetes: A case for gender difference by MARRA, Giampiero, COTRONEO, Patrizia, PITOCCO, Dario, MANTO, Andrea, DI LEO, Mauro A. S, RUOTOLO, Valeria, CAPUTO, Salvatore, GIARDINA, Bruno, GHIRLANDA, Giovanni, SANTINI, Stefano A

“…Diabetes increases the risk of coronary heart disease (CHD) to a greater extent in women than in men. We investigated whether type 1 diabetic patients with…”
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Pharmacogenetics in older people: what we know and what we need to know by Seripa, Davide, Paroni, Giulia, Urbano, Maria, Santini, Stefano A, D'Onofrio, Grazia, Pilotto, Alberto

“…The prevalence of therapeutic failures (TFs) and adverse drug reactions (ADRs) markedly increased in older subjects. However, both TFs and ADRs did not always…”
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Hypouricemia linked to an overproduction of nitric oxide is an early marker of oxidative stress in female subjects with type 1 diabetes by Pitocco, Dario, Di Stasio, Enrico, Romitelli, Federica, Zaccardi, Francesco, Tavazzi, Barbara, Manto, Andrea, Caputo, Salvatore, Musella, Tittania, Zuppi, Cecilia, Santini, Stefano A., Ghirlanda, Giovanni

“…Objective The aim of this study is to verify whether, early in the course of type 1 diabetes and assuming hyperglycemia as the only risk factor, women…”
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Insulin resistance and the cluster of abnormalities related to the metabolic syndrome are associated with reduced glomerular filtration rate in patients with type 2 diabetes by DE COSMO, Salvatore, TREVISAN, Roberto, MINENNA, Antonio, VEDOVATO, Monica, VITI, Raffaella, SANTINI, Stefano A, DODESINI, Alessandro R, FIORETTO, Paola, TRISCHITTA, Vincenzo

“…Because of its devastating outcomes, including end-stage renal disease and increased cardiovascular morbidity and mortality, chronic kidney disease is a…”
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Effectiveness of a high-throughput genetic analysis in the identification of responders/non-responders to CYP2D6-metabolized drugs by Savino, Maria, Seripa, Davide, Gallo, Antonietta P, Garrubba, Maria, D'Onofrio, Grazia, Bizzarro, Alessandra, Paroni, Giulia, Paris, Francesco, Mecocci, Patrizia, Masullo, Carlo, Pilotto, Alberto, Santini, Stefano A

“…Recent studies investigating the single cytochrome P450 (CYP) 2D6 allele *2A reported an association with the response to drug treatments. More genetic data…”
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Myocardial ischemia-reperfusion damage after pacing-induced tachycardia in patients with cardiac syndrome X by Buffon, A, Rigattieri, S, Santini, S A, Ramazzotti, V, Crea, F, Giardina, B, Maseri, A

“…The presence of myocardial ischemia in syndrome X (chest pain, "ischemia-like" electrocardiogram changes, and normal coronary angiograms) is uncertain possibly…”
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Assessment of parathyroid function in clinical practice: Which parathyroid hormone assay is better? by SANTINI, Stefano A, CARROZZA, Cinzia, VULPIO, Carlo, CAPOLUONGO, Ettore, LUCIANI, Giovanna, LULLI, Paola, GIARDINA, Bruno, ZUPPI, Cecilia

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Large, sustained cardiac lipid peroxidation and reduced antioxidant capacity in the coronary circulation after brief episodes of myocardial ischemia by Buffon, Antonino, Santini, Stefano A, Ramazzotti, Vito, Rigattieri, Stefano, Liuzzo, Giovanna, Biasucci, Luigi M, Crea, Filippo, Giardina, Bruno, Maseri, Attilio

“…OBJECTIVES We sought to investigate whether a brief episode of myocardial ischemia produces a detectable cardiac oxidative stress in patients undergoing…”
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Taurine reduces mortality in diabetic rats: taurine and experimental diabetes mellitus by Franconi, Flavia, Santini, Stefano A, Gentiloni Silveri, Nicolò, Caputo, Salvatore, Giardina, Bruno, Ghirlanda, Giovanni, Di Leo, Mauro A S

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Early Increase of Oxidative Stress and Reduced Antioxidant Defenses in Patients With Uncomplicated Type 1 Diabetes by Marra, Giampiero, Cotroneo, Patrizia, Pitocco, Dario, Manto, Andrea, Di Leo, Mauro A.S., Ruotolo, Valeria, Caputo, Salvatore, Giardina, Bruno, Ghirlanda, Giovanni, Santini, Stefano A.

“…Early Increase of Oxidative Stress and Reduced Antioxidant Defenses in Patients With Uncomplicated Type 1 Diabetes A case for gender difference Giampiero Marra…”
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Oxidative Stress, Nitric Oxide, and Diabetes by Pitocco, Dario, Zaccardi, Francesco, Di Stasio, Enrico, Romitelli, Federica, Santini, Stefano A., Zuppi, Cecilia, Ghirlanda, Giovanni

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Paradoxical inhibition of cardiac lipid peroxidation in cancer patients treated with doxorubicin. Pharmacologic and molecular reappraisal of anthracycline cardiotoxicity by Minotti, G, Mancuso, C, Frustaci, A, Mordente, A, Santini, S A, Calafiore, A M, Liberi, G, Gentiloni, N

“…Anticancer therapy with doxorubicin (DOX) and other quinone anthracyclines is limited by severe cardiotoxicity, reportedly because semiquinone metabolites…”
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Chronic pancreatitis (CP) and oxidative stress in pancreatic juice and in peripheric blood by Santini, Stefano A., Spada, Cristiano, Foschia, Francesca, Pandolfi, Monica, Mutignani, Massimiliano, Gentiloni, Niccolò Silveri, Costamagna, Guido

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