Search Results - "Santinho, Alexandre"

Seipin Facilitates Triglyceride Flow to Lipid Droplet and Counteracts Droplet Ripening via Endoplasmic Reticulum Contact by Salo, Veijo T., Li, Shiqian, Vihinen, Helena, Hölttä-Vuori, Maarit, Szkalisity, Abel, Horvath, Peter, Belevich, Ilya, Peränen, Johan, Thiele, Christoph, Somerharju, Pentti, Zhao, Hongxia, Santinho, Alexandre, Thiam, Abdou Rachid, Jokitalo, Eija, Ikonen, Elina

“…Seipin is an oligomeric integral endoplasmic reticulum (ER) protein involved in lipid droplet (LD) biogenesis. To study the role of seipin in LD formation, we…”
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Giant organelle vesicles to uncover intracellular membrane mechanics and plasticity by Santinho, Alexandre, Carpentier, Maxime, Lopes Sampaio, Julio, Omrane, Mohyeddine, Thiam, Abdou Rachid

“…Tools for accessing and studying organelles remain underdeveloped. Here, we present a method by which giant organelle vesicles (GOVs) are generated by…”
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Author Correction: Giant organelle vesicles to uncover intracellular membrane mechanics and plasticity by Santinho, Alexandre, Carpentier, Maxime, Lopes Sampaio, Julio, Omrane, Mohyeddine, Thiam, Abdou Rachid

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Making Droplet-Embedded Vesicles to Model Cellular Lipid Droplets by Chorlay, Aymeric, Santinho, Alexandre, Thiam, Abdou Rachid

“…We present a reproducible protocol to prepare droplet-embedded vesicles (DEVs) consisting of an oil droplet embedded within a phospholipid bilayer. This model…”
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Membrane Curvature Catalyzes Lipid Droplet Assembly by Santinho, Alexandre, Salo, Veijo T., Chorlay, Aymeric, Li, Shiqian, Zhou, Xin, Omrane, Mohyeddine, Ikonen, Elina, Thiam, Abdou Rachid

“…Lipid droplet (LD) biogenesis begins in the endoplasmic reticulum (ER) bilayer, but how the ER topology impacts this process is unclear. An early step in LD…”
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Fat inclusions strongly alter membrane mechanics by Santinho, Alexandre, Chorlay, Aymeric, Foret, Lionel, Thiam, Abdou Rachid

“…Neutral lipids (NLs) are apolar oil molecules synthesized in the endoplasmic reticulum bilayer upon diverse biological stimuli. NLs synthesized are released in…”
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LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy by Omrane, Mohyeddine, Ben M’Barek, Kalthoum, Santinho, Alexandre, Nguyen, Nathan, Nag, Shanta, Melia, Thomas J., Thiam, Abdou Rachid

“…Lipid droplets (LDs) store lipids that can be utilized during times of scarcity via autophagic and lysosomal pathways, but how LDs and autophagosomes interact…”
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