Search Results - "Santillo, Mariarosaria"

The Cu, Zn Superoxide Dismutase: Not Only a Dismutase Enzyme by Mondola, Paolo, Damiano, Simona, Sasso, Anna, Santillo, Mariarosaria

“…The Cu,Zn superoxide dismutase (SOD1) is an ubiquitary cytosolic dimeric carbohydrate free molecule, belonging to a family of isoenzymes involved in the…”
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Dual Role of Reactive Oxygen Species in Muscle Function: Can Antioxidant Dietary Supplements Counteract Age-Related Sarcopenia? by Damiano, Simona, Muscariello, Espedita, La Rosa, Giuliana, Di Maro, Martina, Mondola, Paolo, Santillo, Mariarosaria

“…Sarcopenia is characterized by the progressive loss of skeletal muscle mass and strength. In older people, malnutrition and physical inactivity are often…”
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Dietary Polyphenols, Microbiome, and Multiple Sclerosis: From Molecular Anti-Inflammatory and Neuroprotective Mechanisms to Clinical Evidence by La Rosa, Giuliana, Lonardo, Maria Serena, Cacciapuoti, Nunzia, Muscariello, Espedita, Guida, Bruna, Faraonio, Raffaella, Santillo, Mariarosaria, Damiano, Simona

“…Multiple sclerosis (MS) is a multifactorial, immune-mediated disease caused by complex gene-environment interactions. Dietary factors modulating the…”
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NOX-Dependent Signaling Dysregulation in Severe COVID-19: Clues to Effective Treatments by Damiano, Simona, Sozio, Concetta, La Rosa, Giuliana, Santillo, Mariarosaria

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Metabolism Regulation and Redox State: Insight into the Role of Superoxide Dismutase 1 by Damiano, Simona, Sozio, Concetta, La Rosa, Giuliana, Guida, Bruna, Faraonio, Raffaella, Santillo, Mariarosaria, Mondola, Paolo

“…Energy metabolism and redox state are strictly linked; energy metabolism is a source of reactive oxygen species (ROS) that, in turn, regulate the flux of…”
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Antioxidant, Anti-Inflammatory and Pro-Differentiative Effects of Chlorogenic Acid on M03-13 Human Oligodendrocyte-like Cells by La Rosa, Giuliana, Sozio, Concetta, Pipicelli, Luca, Raia, Maddalena, Palmiero, Anna, Santillo, Mariarosaria, Damiano, Simona

“…Chlorogenic acid (CGA), a polyphenol found mainly in coffee and tea, exerts antioxidant, anti-inflammatory and anti-apoptotic effects at the gastrointestinal…”
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Editorial: Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease by Santillo, Mariarosaria, Pagliaro, Pasquale

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Fasting Drives Nrf2-Related Antioxidant Response in Skeletal Muscle by Lettieri-Barbato, Daniele, Minopoli, Giuseppina, Caggiano, Rocco, Izzo, Rossella, Santillo, Mariarosaria, Aquilano, Katia, Faraonio, Raffaella

“…A common metabolic condition for living organisms is starvation/fasting, a state that could play systemic-beneficial roles. Complex adaptive responses are…”
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A Blood Test for the Diagnosis of Multiple Sclerosis by Giuliano, Paola, La Rosa, Giuliana, Capozzi, Serena, Cassano, Emanuele, Damiano, Simona, Habetswallner, Francesco, Iodice, Rosa, Marra, Maurizio, Pavone, Luigi Michele, Quarantelli, Mario, Vitelli, Giuseppe, Santillo, Mariarosaria, Paternò, Roberto

“…Multiple sclerosis (MS) is an autoimmune chronic disease characterized by inflammation and demyelination of the central nervous system (CNS). Despite numerous…”
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Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis by Svegliati Baroni, Silvia, Santillo, Mariarosaria, Bevilacqua, Federica, Luchetti, Michele, Spadoni, Tatiana, Mancini, Matteo, Fraticelli, Paolo, Sambo, Paola, Funaro, Ada, Kazlauskas, Andrius, Avvedimento, Enrico V, Gabrielli, Armando

“…The pathophysiology of systemic sclerosis (scleroderma), an autoimmune disease characterized by injury of endothelial cells, and tissue fibrosis, is undefined…”
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Quercetin Increases MUC2 and MUC5AC Gene Expression and Secretion in Intestinal Goblet Cell-Like LS174T via PLC/PKCα/ERK1-2 Pathway by Damiano, Simona, Sasso, Anna, De Felice, Bruna, Di Gregorio, Ilaria, La Rosa, Giuliana, Lupoli, Gelsi A, Belfiore, Anna, Mondola, Paolo, Santillo, Mariarosaria

“…The main dietary flavonoid quercetin, is known to preserve the integrity of gastrointestinal barrier and to have anti-inflammatory, anti-cancer, anti-fibrotic,…”
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5-Hydroxytryptamine Modulates Maturation and Mitochondria Function of Human Oligodendrocyte Progenitor M03-13 Cells by Damiano, Simona, La Rosa, Giuliana, Sozio, Concetta, Cavaliere, Gina, Trinchese, Giovanna, Raia, Maddalena, Paternò, Roberto, Mollica, Maria Pina, Avvedimento, Vittorio Enrico, Santillo, Mariarosaria

“…Inside the adult CNS, oligodendrocyte progenitor cells (OPC ) are able to proliferate, migrate and differentiate into mature oligodendrocytes (OLs) which are…”
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The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19 by Di Maro, Martina, Cataldi, Mauro, Santillo, Mariarosaria, Chiurazzi, Martina, Damiano, Simona, De Conno, Barbara, Colantuoni, Antonio, Guida, Bruna

“…The renin angiotensin system and the cholinergic anti-inflammatory pathway have been recently shown to modulate lung inflammation in patients with COVID-19. We…”
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Insights on the Multifaceted Roles of Wild-Type and Mutated Superoxide Dismutase 1 in Amyotrophic Lateral Sclerosis Pathogenesis by Rubino, Valentina, La Rosa, Giuliana, Pipicelli, Luca, Carriero, Flavia, Damiano, Simona, Santillo, Mariarosaria, Terrazzano, Giuseppe, Ruggiero, Giuseppina, Mondola, Paolo

“…Amyotrophic Lateral Sclerosis (ALS) is a progressive motor neurodegenerative disease. Cell damage in ALS is the result of many different, largely unknown,…”
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Effect of Mutated Cu, Zn Superoxide Dismutase (SOD1 G93A ) on Modulation of Transductional Pathway Mediated by M1 Muscarinic Receptor in SK-N-BE and NSC-34 Cells by Damiano, Simona, Sasso, Anna, Accetta, Roberta, Monda, Marcellino, De Luca, Bruno, Pavone, Luigi Michele, Belfiore, Anna, Santillo, Mariarosaria, Mondola, Paolo

“…The constitutive secretion of antioxidant Cu-Zn Superoxide dismutase (SOD1) has been widely demonstrated in many cellular lines. In addition, we showed that as…”
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Superoxide Dismutase-1 Intracellular Content in T Lymphocytes Associates with Increased Regulatory T Cell Level in Multiple Sclerosis Subjects Undergoing Immune-Modulating Treatment by Rubino, Valentina, Palatucci, Anna Teresa, La Rosa, Giuliana, Giovazzino, Angela, Aruta, Francesco, Damiano, Simona, Carriero, Flavia, Santillo, Mariarosaria, Iodice, Rosa, Mondola, Paolo, Ruggiero, Giuseppina, Terrazzano, Giuseppe

“…Reactive oxygen species (ROS) participate in the T-cell activation processes. ROS-dependent regulatory networks are usually mediated by peroxides, which are…”
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Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells by Damiano, Simona, Fusco, Roberta, Morano, Annalisa, De Mizio, Mariarosaria, Paternò, Roberto, De Rosa, Antonella, Spinelli, Rosa, Amente, Stefano, Frunzio, Rodolfo, Mondola, Paolo, Miot, Francoise, Laccetti, Paolo, Santillo, Mariarosaria, Avvedimento, Enrico Vittorio

“…Dual Oxidases (DUOX) 1 and 2 are efficiently expressed in thyroid, gut, lung and immune system. The function and the regulation of these enzymes in mammals are…”
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The Effects of Angiotensin II or Angiotensin 1-7 on Rat Pial Microcirculation during Hypoperfusion and Reperfusion Injury: Role of Redox Stress by Lapi, Dominga, Cammalleri, Maurizio, Dal Monte, Massimo, Di Maro, Martina, Santillo, Mariarosaria, Belfiore, Anna, Nasti, Gilda, Damiano, Simona, Trio, Rossella, Chiurazzi, Martina, De Conno, Barbara, Serao, Nicola, Mondola, Paolo, Colantuoni, Antonio, Guida, Bruna

“…Renin-angiotensin systems produce angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7), which are able to induce opposite effects on circulation. This study…”
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Oxidative stress and the pathogenesis of scleroderma: the Murrell’s hypothesis revisited by Gabrielli, Armando, Svegliati, Silvia, Moroncini, Gianluca, Pomponio, Giovanni, Santillo, Mariarosaria, Avvedimento, Enrico V.

“…Systemic sclerosis (SSc, scleroderma) is a devastating, immune-mediated, multisystem disorder characterized by microvasculature damage, circulating…”
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Rab4 affects both recycling and degradative endosomal trafficking by McCaffrey, Mary W., Bielli, Anna, Cantalupo, Giuseppina, Mora, Silvia, Roberti, Vera, Santillo, Mariarosaria, Drummond, Frances, Bucci, Cecilia

“…The small GTPases Rab4, Rab5 and Rab7 are endosomal proteins which play important roles in the regulation of various stages of endosomal trafficking. Rab4 and…”
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