Search Results - "Santibanez Juan F."

Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells by Kocić, Jelena, Santibanez, Juan F.

“…Transforming growth factor-beta (TGF-β) is a pleiotropic factor with several different roles in health and disease. In tumorigenesis, it may act as a…”
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Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression by Santibanez, Juan F., Mojsilović, Slavko, Trivanović, Drenka, Kocić, Jelena

“…Transforming growth factor-beta (TGF-β) and oxidative stress/Reactive Oxygen Species (ROS) both have pivotal roles in health and disease. In this review we are…”
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ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion by Tobar, Nicolas, Villar, Victor, Santibanez, Juan F

“…TGF-β1 has been postulated as a pro-oncogenic factor in the late step of the tumoral progression. In transformed cells, TGF-β1 enhances the capacity to degrade…”
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Urokinase Type Plasminogen Activator and the Molecular Mechanisms of its Regulation in Cancer by Santibanez, Juan F

“…Urokinase type plasminogen activator (uPA) is a 53-kDa serine protease initially synthesized as a catalytically inactive single chain polypeptide. Inactive-uPA…”
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Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention by Ruzic, Dusan, Djoković, Nemanja, Srdić-Rajić, Tatjana, Echeverria, Cesar, Nikolic, Katarina, Santibanez, Juan F

“…The dysregulation of gene expression is a critical event involved in all steps of tumorigenesis. Aberrant histone and non-histone acetylation modifications of…”
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Current and Future Cancer Chemoprevention Strategies by Santibanez, Juan F, Villar, Victor H, Echeverria, Cesar

“…Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 and ranking as the second-leading cause of death in economically…”
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Metabolic Plasticity of Stem Cells and Macrophages in Cancer by Krstic, Jelena, Trivanovic, Drenka, Jaukovic, Aleksandra, Santibanez, Juan F, Bugarski, Diana

“…In addition to providing essential molecules for the overall function of cells, metabolism plays an important role in cell fate and can be affected by…”
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VEGF Regulation of Angiogenic Factors via Inflammatory Signaling in Myeloproliferative Neoplasms by Subotički, Tijana, Mitrović Ajtić, Olivera, Živković, Emilija, Diklić, Miloš, Đikić, Dragoslava, Tošić, Milica, Beleslin-Čokić, Bojana, Dragojević, Teodora, Gotić, Mirjana, Santibanez, Juan F., Čokić, Vladan

“…Background: Chronic inflammation has been recognized in neoplastic disorders, including myeloproliferative neoplasm (MPN), as an important regulator of…”
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Interactions among myeloid regulatory cells in cancer by Umansky, Viktor, Adema, Gosse J., Baran, Jaroslaw, Brandau, Sven, Van Ginderachter, Jo A., Hu, Xiaoying, Jablonska, Jadwiga, Mojsilovic, Slavko, Papadaki, Helen A., Pico de Coaña, Yago, Santegoets, Kim C. M., Santibanez, Juan F., Serre, Karine, Si, Yu, Sieminska, Isabela, Velegraki, Maria, Fridlender, Zvi G.

“…© Springer-Verlag GmbH Germany, part of Springer Nature 2018 Mounting evidence has accumulated on the critical role of the different myeloid cells in the…”
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Mesenchymal stromal cells in myeloid malignancies: Immunotherapeutic opportunities by Vukotić, Milica, Kapor, Suncica, Simon, Felipe, Cokic, Vladan, Santibanez, Juan F.

“…Myeloid malignancies are clonal disorders of the progenitor cells or hematopoietic stem cells, including acute myeloid leukemia, myelodysplastic syndromes,…”
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Transforming Growth Factor-Beta and Urokinase Type Plasminogen Interplay in Cancer by Santibanez, Juan F, Krstic, Jelena

“…Transforming growth factor-beta (TGF-β) is well recognized as playing a double role in tumor progression. Its antitumor role takes place in the early stages of…”
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Mesenchymal stromal cell engagement in cancer cell epithelial to mesenchymal transition by Trivanović, Drenka, Krstić, Jelena, Jauković, Aleksandra, Bugarski, Diana, Santibanez, Juan F.

“…Due to coexistence of stromal and epithelial tumor cells, their dynamic interactions have been widely recognized as significant cellular components to the…”
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Regulation of Mesenchymal Stem Cell Differentiation by Transforming Growth Factor Beta Superfamily by Krstic, Jelena, Trivanovic, Drenka, Obradovic, Hristina, Kukolj, Tamara, Bugarski, Diana, Santibanez, Juan F

“…The ability to differentiate into cells of different lineage, such as muscle, bone, cartilage and fat, is the chief value of adult mesenchymal stem cells…”
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Discovery of 1-Benzhydryl-Piperazine-Based HDAC Inhibitors with Anti-Breast Cancer Activity: Synthesis, Molecular Modeling, In Vitro and In Vivo Biological Evaluation by Ruzic, Dusan, Ellinger, Bernhard, Djokovic, Nemanja, Santibanez, Juan F, Gul, Sheraz, Beljkas, Milan, Djuric, Ana, Ganesan, Arasu, Pavic, Aleksandar, Srdic-Rajic, Tatjana, Petkovic, Milos, Nikolic, Katarina

“…Isoform-selective histone deacetylase (HDAC) inhibition is promoted as a rational strategy to develop safer anti-cancer drugs compared to non-selective HDAC…”
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SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes by Kocic, Jelena, Bugarski, Diana, Santibanez, Juan F

“…Abstract Transforming growth factor-β1 (TGF-β1) stimulates the extracellular matrix degrading proteases expression and cell migration in order to enhance…”
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Effect of Dietary Supplements with ω-3 Fatty Acids, Ascorbic Acid, and Polyphenolic Antioxidant Flavonoid on Gene Expression, Organ Failure, and Mortality in Endotoxemia-Induced Septic Rats by Prado, Yolanda, Echeverría, Cesar, Feijóo, Carmen G, Riedel, Claudia A, Cabello-Verrugio, Claudio, Santibanez, Juan F, Simon, Felipe

“…Sepsis syndrome develops through enhanced secretion of pro-inflammatory cytokines and the generation of reactive oxygen species (ROS). Sepsis syndrome is…”
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The Metabolic Features of Tumor-Associated Macrophages: Opportunities for Immunotherapy? by Mojsilovic, Sonja S., Mojsilovic, Slavko, Villar, Victor H., Santibanez, Juan F.

“…Besides transformed cells, the tumors are composed of various cell types that contribute to undesirable tumor progression. Tumor-associated macrophages (TAMs)…”
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In Vivo and in vitro antitumor activity of tomatine in hepatocellular carcinoma by Echeverría, Cesar, Martin, Aldo, Simon, Felipe, Salas, Cristian O., Nazal, Mariajesus, Varela, Diego, Pérez-Castro, Ramón A., Santibanez, Juan F., Valdés-Valdés, Ricardo O., Forero-Doria, Oscar, Echeverría, Javier

“…Background: There is abundant ethnopharmacological evidence the uses of regarding Solanum species as antitumor and anticancer agents. Glycoalkaloids are among…”
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Host-guest interactions of coumarin-based 1,2-pyrazole using analytical and computational methods: Paper strip-based detection, live cell imaging, logic gates and keypad lock applications by Rasin, Puthiyavalappil, Basheer, Sabeel M., Haribabu, Jebiti, Aneesrahman, K.N., Manakkadan, Vipin, Vadakkedathu Palakkeezhillam, Vishnunarayanan Namboothiri, Bhuvanesh, Nattamai, Echeverria, Cesar, Santibanez, Juan F., Sreekanth, Anandaram

“…A novel Coumarin-based 1,2-pyrazole, HCPyTSC is synthesised and characterized. The chemosensor has been shown to have efficient colourimetric and fluorescence…”
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Nitric Oxide Mediation in Hydroxyurea and Nitric Oxide Metabolites' Inhibition of Erythroid Progenitor Growth by Subotički, Tijana, Mitrović Ajtić, Olivera, Djikić, Dragoslava, Kovačić, Marijana, Santibanez, Juan F, Tošić, Milica, Čokić, Vladan P

“…In several systems, hydroxyurea has been shown to trigger nitric oxide (NO) release or activation of NO synthase (NOS). To elucidate this duality in its…”
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