Search Results - "Santiago, Marina"

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    Inhibition of human recombinant T‐type calcium channels by phytocannabinoids in vitro by Mirlohi, Somayeh, Bladen, Chris, Santiago, Marina J., Arnold, Jonathon C., McGregor, Iain, Connor, Mark

    Published in British journal of pharmacology (01-08-2022)
    “…Background and Purpose T‐type Ca channels (ICa) regulate neuronal excitability and contribute to neurotransmitter release. The phytocannabinoids…”
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    Journal Article
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    Triggered Drug Release From Liposomes: Exploiting the Outer and Inner Tumor Environment by Franco, Marina Santiago, Gomes, Eliza Rocha, Roque, Marjorie Coimbra, Oliveira, Mônica Cristina

    Published in Frontiers in oncology (16-03-2021)
    “…Since more than 40 years liposomes have being extensively studied for their potential as carriers of anticancer drugs. The basic principle behind their use for…”
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    Histidine transport is essential for the growth of Staphylococcus aureus at low pH by Beetham, Catrin M, Schuster, Christopher F, Kviatkovski, Igor, Santiago, Marina, Walker, Suzanne, Gründling, Angelika

    Published in PLoS pathogens (16-01-2024)
    “…Staphylococcus aureus is an opportunistic pathogen capable of causing many different human diseases. During colonization and infection, S. aureus will…”
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    Distinct Fecal and Plasma Metabolites in Children with Autism Spectrum Disorders and Their Modulation after Microbiota Transfer Therapy by Kang, Dae-Wook, Adams, James B., Vargason, Troy, Santiago, Marina, Hahn, Juergen, Krajmalnik-Brown, Rosa

    Published in mSphere (21-10-2020)
    “…Despite the prevalence of autism and its extensive impact on our society, no U.S. Food and Drug Administration-approved treatment is available for this complex…”
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    Combining Nanocarrier-Assisted Delivery of Molecules and Radiotherapy by Gomes, Eliza Rocha, Franco, Marina Santiago

    Published in Pharmaceutics (03-01-2022)
    “…Cancer is responsible for a significant proportion of death all over the world. Therefore, strategies to improve its treatment are highly desired. The use of…”
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    16S rRNA sequencing of samples from universal stool bank donors by Santiago, Marina, Olesen, Scott W

    Published in BMC research notes (23-03-2021)
    “…Universal stool banks provide stool to physicians for use in treating recurrent Clostridioides difficile infection via fecal microbiota transplantation. Stool…”
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    Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis by Franco, Marina Santiago, Youn, Yu Seok

    Published in Pharmaceutics (13-04-2022)
    “…Since clinical approval of the first liposomal formulation encapsulating a chemotherapeutic agent, nanoscale delivery systems have been a rapidly developing…”
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    A new platform for ultra-high density Staphylococcus aureus transposon libraries by Santiago, Marina, Matano, Leigh M, Moussa, Samir H, Gilmore, Michael S, Walker, Suzanne, Meredith, Timothy C

    Published in BMC genomics (29-03-2015)
    “…Staphylococcus aureus readily develops resistance to antibiotics and achieving effective therapies to overcome resistance requires in-depth understanding of S…”
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    Tapentadol shows lower intrinsic efficacy at µ receptor than morphine and oxycodone by Manandhar, Preeti, Connor, Mark, Santiago, Marina

    Published in Pharmacology research & perspectives (01-02-2022)
    “…Tapentadol is a centrally acting analgesic with a dual mechanism of action. It acts as an agonist at the µ receptor and inhibitor of noradrenaline reuptake…”
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    Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries by Rajagopal, Mithila, Martin, Melissa J, Santiago, Marina, Lee, Wonsik, Kos, Veronica N, Meredith, Tim, Gilmore, Michael S, Walker, Suzanne

    Published in mBio (16-08-2016)
    “…Staphylococcus aureus is a leading cause of life-threatening infections worldwide. The MIC of an antibiotic against S. aureus, as well as other microbes, is…”
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    Short and Long-Term Effects of the Exposure of Breast Cancer Cell Lines to Different Ratios of Free or Co-Encapsulated Liposomal Paclitaxel and Doxorubicin by Franco, Marina Santiago, Roque, Marjorie Coimbra, Oliveira, Mônica Cristina

    Published in Pharmaceutics (11-04-2019)
    “…Associating paclitaxel (PTX) to doxorubicin (DXR) is one of the main chemotherapy strategies for breast cancer (BC) management. Protocols currently available…”
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    Do gabapentin or pregabalin directly modulate the µ receptor? by Manandhar, Preeti, Murnion, Bridin Patricia, Grimsey, Natasha L, Connor, Mark, Santiago, Marina

    Published in PeerJ (San Francisco, CA) (12-04-2021)
    “…Pregabalin and gabapentin improve neuropathic pain symptoms but there are emerging concerns regarding their misuse. This is more pronounced among patients with…”
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    Impact of probiotic Veillonella atypica FB0054 supplementation on anaerobic capacity and lactate by Gross, Kristen, Santiago, Marina, Krieger, Joesi M., Hagele, Anthony M., Zielinska, Kinga, Scheiman, Jonathan, Jäger, Ralf, Kostic, Alex, Kerksick, Chad M.

    Published in iScience (19-01-2024)
    “…Seven healthy, physically active men (n = 3) and women (n = 4) (30.7 ± 7.5 years, 172.7 ± 8.7 cm, 70.4 ± 11.6 kg, 23.6 ± 4.1 kg/m2, 49.2 ± 8.4 mL/kg/min)…”
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    Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells by Sachdev, Shivani, Boyd, Rochelle, Grimsey, Natasha L, Santiago, Marina, Connor, Mark

    Published in PeerJ (San Francisco, CA) (25-09-2019)
    “…Synthetic cannabinoids are a commonly used class of recreational drugs that can have significant adverse effects. There have been sporadic reports of…”
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    Differential activation of G protein‐mediated signaling by synthetic cannabinoid receptor agonists by Sachdev, Shivani, Banister, Samuel D., Santiago, Marina, Bladen, Chris, Kassiou, Michael, Connor, Mark

    Published in Pharmacology research & perspectives (01-04-2020)
    “…Synthetic cannabinoid receptor agonists (SCRAs) are new psychoactive substances associated with acute intoxication and even death. However, the molecular…”
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