Search Results - "Santiago, Leonardo Freire"
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Recombinant T‐cell epitope conjugation: A new approach for Dermatophagoides hypoallergen design
Published in Clinical and experimental allergy (01-02-2023)“…Background Allergen‐specific immunotherapy (AIT) is the only clinical approach that can potentially cure some allergic diseases by inducing immunological…”
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The hybrid protein BTH2 suppresses allergic airway inflammation in a murine model of HDM‐specific immunotherapy
Published in Clinical and experimental allergy (01-08-2023)“…Background Allergen‐specific immunotherapy (AIT) is the only disease‐modifying treatment approach to change disease‐causing allergens. Hypoallergenic…”
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Immunogenicity and protection induced by recombinant Toxocara canis proteins in a murine model of toxocariasis
Published in Vaccine (19-06-2020)“…•In Silico data were used for the selection of T. canis antigens as vaccine candidate.•T. canis recombinant antigens were used effectively for the control of…”
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Proteomics and immunoblotting analyses reveal antigens that optimize the immunodiagnosis of the infection by Toxocara spp
Published in Transboundary and emerging diseases (01-09-2022)“…Toxocariasis is an infection caused by the round worms Toxocara canis and Toxocara cati. It occurs worldwide though it is more prevalent in developing…”
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Therapeutic potential of a novel hybrid protein: Mitigating allergy and airway remodeling in chronic asthma models induced by Dermatophagoides pteronyssinus
Published in Molecular immunology (01-11-2024)“…The house-dust mite Dermatophagoides pteronyssinus is a key trigger of allergic asthma. Therefore, it is essential to develop new vaccines that can alter…”
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