Search Results - "Santi, Isabella"
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1
Evolution of Antibiotic Tolerance Shapes Resistance Development in Chronic Pseudomonas aeruginosa Infections
Published in mBio (09-02-2021)“…The widespread use of antibiotics promotes the evolution and dissemination of resistance and tolerance mechanisms. To assess the relevance of tolerance and its…”
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Journal Article -
2
Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria
Published in Nature communications (16-09-2013)“…During the bacterial cell cycle, chromosome replication and cell division must be coordinated with overall cell growth in order to maintain the correct ploidy…”
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Journal Article -
3
Chromosome organization and replisome dynamics in Mycobacterium smegmatis
Published in mBio (17-02-2015)“…Subcellular organization of the bacterial nucleoid and spatiotemporal dynamics of DNA replication and segregation have been studied intensively, but the…”
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4
Identification of novel genomic islands coding for antigenic pilus‐like structures in Streptococcus agalactiae
Published in Molecular microbiology (01-07-2006)“…Summary We have recently reported the presence of covalently linked pilus‐like structures in the human pathogen, Group B Streptococcus (GBS). The pilus operon…”
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Journal Article -
5
CsrRS Regulates Group B Streptococcus Virulence Gene Expression in Response to Environmental pH: a New Perspective on Vaccine Development
Published in Journal of Bacteriology (01-09-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
Adaptive response of Group B streptococcus to high glucose conditions: new insights on the CovRS regulation network
Published in PloS one (09-04-2013)“…Although the contribution of carbohydrate catabolism to bacterial colonization and infection is well recognized, the transcriptional changes during these…”
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Journal Article -
7
Group B Streptococcus Pullulanase Crystal Structures in the Context of a Novel Strategy for Vaccine Development
Published in Journal of Bacteriology (01-06-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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8
Functional characterization of a newly identified group B Streptococcus pullulanase eliciting antibodies able to prevent alpha-glucans degradation
Published in PloS one (21-11-2008)“…Streptococcal pullulanases have been recently proposed as key components of the metabolic machinery involved in bacterial adaptation to host niches. By…”
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Journal Article -
9
The Use of Experimental Evolution to Study the Response of Pseudomonas aeruginosa to Single or Double Antibiotic Treatment
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…The widespread use of antibiotics promotes the evolution and dissemination of drug resistance and tolerance. Both mechanisms promote survival during antibiotic…”
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10
An Analysis of Indoor Air Quality at cal Poly for Sensor Design
Published 01-01-2024“…Prior research has shown that indoor air quality (IAQ) impacts cognitive performance. At Cal Poly, many older buildings are unable to maintain appropriate IAQ…”
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Dissertation -
11
Toxin-mediated depletion of NAD and NADP drives persister formation in a human pathogen
Published in The EMBO journal (25-09-2024)“…Toxin–antitoxin (TA) systems are widespread in bacteria and implicated in genome stability, virulence, phage defense, and persistence. TA systems have diverse…”
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Journal Article -
12
Defining Proteomic Signatures to Predict Multidrug Persistence in Pseudomonas aeruginosa
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Bacterial persisters are difficult to eradicate because of their ability to survive prolonged exposure to a range of different antibiotics. Because they often…”
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Journal Article -
13
The studies of ParA and ParB dynamics reveal asymmetry of chromosome segregation in mycobacteria
Published in Molecular microbiology (01-08-2017)“…Summary Active segregation of bacterial chromosomes usually involves the action of ParB proteins, which bind in proximity of chromosomal origin (oriC) regions…”
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Journal Article -
14
Erratum: Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria
Published in Nature communications (03-12-2013)“…Nature Communications 4: Article number: 2470 (2013); Published: 16 September 2013; Updated: 03 December 2013 There were errors associated with the…”
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Journal Article -
15
BibA: a novel immunogenic bacterial adhesin contributing to group B Streptococcus survival in human blood
Published in Molecular microbiology (01-02-2007)“…By the analysis of the recently sequenced genomes of Group B Streptococcus (GBS) we have identified a novel immunogenic adhesin with anti-phagocytic activity,…”
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Journal Article -
16
Identification of aminopyrimidine‐sulfonamides as potent modulators of Wag31‐mediated cell elongation in mycobacteria
Published in Molecular microbiology (01-01-2017)“…Summary There is an urgent need to discover new anti‐tubercular agents with novel mechanisms of action in order to tackle the scourge of drug‐resistant…”
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Journal Article -
17
Pilus Backbone Contributes to Group B Streptococcus Paracellular Translocation through Epithelial Cells
Published in The Journal of infectious diseases (15-09-2008)“…We have recently shown that group B Streptococcus (GBS) crosses the epithelial barrier by a paracellular route. Here, we show that, although deletion of the…”
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Journal Article -
18
BibA Induces Opsonizing Antibodies Conferring In Vivo Protection against Group B Streptococcus
Published in The Journal of infectious diseases (15-08-2009)“…We recently characterized the function of BibA, an immunogenic surface-associated antigen expressed by group B Streptococcus (GBS) that is involved in…”
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Journal Article -
19
Group B Streptococcus Crosses Human Epithelial Cells by a Paracellular Route
Published in The Journal of infectious diseases (15-01-2006)“…Colonization of the colon and vagina is thought to be important in the pathogenesis of group B Streptococcus (GBS) infection. However, little is known about…”
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Journal Article -
20
BibA: a novel immunogenic bacterial adhesin contributing to group B Streptococcus survival in human blood
Published in Molecular microbiology (01-02-2007)“…By the analysis of the recently sequenced genomes of Group B Streptococcus (GBS) we have identified a novel immunogenic adhesin with anti-phagocytic activity,…”
Get full text
Journal Article