Search Results - "Santhakumar, Diwakar"

Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities by Santhakumar, Diwakar, Iqbal, Munir, Nair, Venugopal, Munir, Muhammad

“…Interferons (IFNs) are essential components of the host innate immune system and define first-line of defence against pathogens. In mammals, several type I…”
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Chicken Interferon-induced Protein with Tetratricopeptide Repeats 5 Antagonizes Replication of RNA Viruses by Santhakumar, Diwakar, Rohaim, Mohammed Abdel Mohsen Shahaat, Hussein, Hussein A., Hawes, Pippa, Ferreira, Helena Lage, Behboudi, Shahriar, Iqbal, Munir, Nair, Venugopal, Arns, Clarice W., Munir, Muhammad

“…The intracellular actions of interferon (IFN)-regulated proteins, including IFN-induced proteins with tetratricopeptide repeats (IFITs), attribute a major…”
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Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target by Libri, Valentina, Helwak, Aleksandra, Miesen, Pascal, Santhakumar, Diwakar, Borger, Jessica G, Kudla, Grzegorz, Grey, Finn, Tollervey, David, Buck, Amy H

“…Individual microRNAs (miRNAs) are rapidly down-regulated during conditions of cellular activation and infection, but factors mediating miRNA turnover are…”
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Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease Viruses by Rohaim, Mohammed A, Santhakumar, Diwakar, Naggar, Rania F El, Iqbal, Munir, Hussein, Hussein A, Munir, Muhammad

“…Innate antiviral immunity establishes first line of defense against invading pathogens through sensing their molecular structures such as viral RNA. This…”
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Combined agonist–antagonist genome-wide functional screening identifies broadly active antiviral microRNAs by Santhakumar, Diwakar, Forster, Thorsten, Laqtom, Nouf N., Fragkoudis, Rennos, Dickinson, Paul, Abreu-Goodger, Cei, Manakov, Sergei A., Choudhury, Nila Roy, Griffiths, Samantha J., Vermeulen, Annaleen, Enright, Anton J., Dutia, Bernadette, Kohl, Alain, Ghazal, Peter, Buck, Amy H., Pace, Norman R.

“…Although the functional parameters of microRNAs (miRNAs) have been explored in some depth, the roles of these molecules in viral infections remain elusive…”
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Genome-Wide Classification of Type I, Type II and Type III Interferon-Stimulated Genes in Chicken Fibroblasts by Santhakumar, Diwakar, Rohaim, Mohammed A, Munir, Muhammad

“…Interferons (IFNs) play central roles in establishing innate immunity and mediating adaptive immunity against multiple pathogens. Three known types of IFNs…”
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Avian Interferons and Their Antiviral Effectors by Santhakumar, Diwakar, Rubbenstroth, Dennis, Martinez-Sobrido, Luis, Munir, Muhammad

“…Interferon (IFN) responses, mediated by a myriad of IFN-stimulated genes (ISGs), are the most profound innate immune responses against viruses. Cumulatively,…”
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Infectivity of wild bird-origin avian paramyxovirus serotype 1 and vaccine effectiveness in chickens by Shabbir, Muhammad Zubair, Akhtar, Sameera, Tang, Yi, Yaqub, Tahir, Ahmad, Arfan, Mustafa, Ghulam, Alam, Muhammad Azhar, Santhakumar, Diwakar, Nair, Venugopal, Munir, Muhammad

“…Newcastle disease virus, a prototype avian paramyxovirus serotype 1 (APMV-1), causes economically devastating disease in avian species around the world…”
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Dynamic Expression of Interferon Lambda Regulated Genes in Primary Fibroblasts and Immune Organs of the Chicken by Arslan, Mehboob, Yang, Xin, Santhakumar, Diwakar, Liu, Xingjian, Hu, Xiaoyuan, Munir, Muhammad, Li, Yinü, Zhang, Zhifang

“…Interferons (IFNs) are pleiotropic cytokines that establish a first line of defense against viral infections in vertebrates. Several types of IFN have been…”
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Delivery and function of anti-viral mir-542-5p in vivo by Santhakumar, Diwakar

“…MicroRNAs (miRNAs) have been identified as a key regulator in various biological processes and different diseases including cancer, heart disease, and viral…”
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