Search Results - "Santangelo, B"
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Intranasal dexmedetomidine in healthy beagles: An echocardiographic and pharmacokinetic/pharmacodynamic study
Published in The veterinary journal (1997) (01-09-2019)“…•Intranasal administration is an alternative route of administration for dexmedetomidine in dogs.•Compared to the IM route, intranasal administration of…”
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Plasma concentrations and sedative effects of a dexmedetomidine, midazolam, and butorphanol combination after transnasal administration in healthy rabbits
Published in Journal of veterinary pharmacology and therapeutics (01-08-2016)“…Plasma concentrations of dexmedetomidine (D = 0.1 mg/kg), midazolam (M = 2 mg/kg), and butorphanol (B = 0.4 mg/kg) were analyzed by liquid chromatography–mass…”
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Postvaccination immunity against hepatitis B virus in children
Published in Digestive and liver disease (08-10-2015)Get full text
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Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function
Published in Nature immunology (01-12-2022)“…Increasing evidence indicates close interaction between immune cells and the brain, revising the traditional view of the immune privilege of the brain…”
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Histone deacetylase 3 is required for iNKT cell development
Published in Scientific reports (19-07-2017)“…NKT cells are a distinct subset that have developmental requirements that often differ from conventional T cells. Here, we show that NKT-specific deletion of…”
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Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue
Published in Nature immunology (01-01-2015)“…i NKT cells in adipose tissue are anti-inflammatory. Brenner and colleagues show that adipose i NKT cells have a unique transcriptional program, produce IL-2…”
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Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer
Published in Proceedings of the National Academy of Sciences - PNAS (14-01-2020)“…Reprogramming the tumor microenvironment to increase immune-mediated responses is currently of intense interest. Patients with immune-infiltrated “hot” tumors…”
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Adolescents and caffeine containing beverages: To take or not to take energy drinks?
Published in Digestive and liver disease (30-09-2013)Get full text
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Transcriptional control of invariant NKT cell development
Published in Immunological reviews (01-11-2010)“…Invariant natural killer T (iNKT) cells comprise a rare lymphocyte sublineage with phenotypic and functional properties similar to T and NK cells. Akin to…”
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The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system
Published in The Journal of immunology (1950) (15-09-2011)“…Successful immunity depends upon the activity of multiple cell types. Commitment of pluripotent precursor cells to specific lineages, such as T or B cells, is…”
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The MHC Class II Antigen-Processing and Presentation Pathway Is Dysregulated in Type 1 Diabetes
Published in The Journal of immunology (1950) (01-12-2023)“…Peptide loading of MHC class II (MHCII) molecules is facilitated by HLA-DM (DM), which catalyzes CLIP release, stabilizes empty MHCII, and edits the…”
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A SARS-CoV-2 Vaccine Designed for Manufacturability Results in Unexpected Potency and Non-Waning Humoral Response
Published in Vaccines (Basel) (01-04-2023)“…The rapid development of several highly efficacious SARS-CoV-2 vaccines was an unprecedented scientific achievement that saved millions of lives. However, now…”
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Development of PLZF-expressing innate T cells
Published in Current opinion in immunology (01-04-2011)“…Recent studies have shown that the transcriptional regulator promyelocytic leukemia zinc finger (PLZF) controls the development of essentially all of the…”
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YY1lo NKT cells are dedicated IL-10 producers
Published in Scientific reports (03-03-2020)“…Co-expression of Yin Yang 1 (YY1) is required for the full function of the transcription factor, PLZF, which is essential for the development of natural killer…”
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Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling
Published in Scientific reports (16-07-2015)“…The transcription factor PLZF (promyelocytic leukemia zinc finger; zbtb16 ) is essential for nearly all of the unique characteristics of NKT cells including…”
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Dexmedetomidine chemical restraint of two raptor species undergoing inhalation anaesthesia
Published in Veterinary research communications (01-09-2009)“…Issue Title: LXII ANNUAL MEETING of the ITALIAN SOCIETY for VETERINARY SCIENCES (SISVET), San Benedetto del Tronto (Ascoli Piceno) 2008…”
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Coexpression of YY1 Is Required to Elaborate the Effector Functions Controlled by PLZF in NKT Cells
Published in The Journal of immunology (1950) (01-08-2019)“…The promyelocytic leukemia zinc-finger transcription factor (PLZF) is essential for nearly all of the unique, innate-like functions and characteristics of NKT…”
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Integrative scATAC-seq and scRNA-seq analyses map thymic iNKT cell development and identify Cbfβ for its commitment
Published in Cell discovery (20-06-2023)“…Unlike conventional αβT cells, invariant natural killer T ( i NKT) cells complete their terminal differentiation to functional i NKT1/2/17 cells in the thymus…”
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Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus
Published in PloS one (10-12-2013)“…Thymic microenvironments are essential for the proper development and selection of T cells critical for a functional and self-tolerant adaptive immune…”
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Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53
Published in The Journal of immunology (1950) (15-03-2016)“…Yin Yang 1 (YY1) is a zinc finger protein that functions as a transcriptional activator or repressor and participates in multiple biological processes,…”
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