Search Results - "Santana Rodríguez, R."

Differential asthma odds following respiratory infection in children from three minority populations by Wohlford, Eric M, Borrell, Luisa N, Elhawary, Jennifer R, Plotkin, Brian, Oh, Sam S, Nuckton, Thomas J, Eng, Celeste, Salazar, Sandra, LeNoir, Michael A, Meade, Kelley, Farber, Harold J, Serebrisky, Denise, Brigino-Buenaventura, Emerita, Rodriguez-Cintron, William, Kumar, Rajesh, Thyne, Shannon, Seibold, Max A, Rodríguez-Santana, José R, Burchard, Esteban G

“…Severe early-life respiratory illnesses, particularly those caused by respiratory syncytial virus (RSV) and human rhinovirus (HRV), are strongly associated…”
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Race and Genetic Ancestry in Medicine — A Time for Reckoning with Racism by Borrell, Luisa N, Elhawary, Jennifer R, Fuentes-Afflick, Elena, Witonsky, Jonathan, Bhakta, Nirav, Wu, Alan H.B, Bibbins-Domingo, Kirsten, Rodríguez-Santana, José R, Lenoir, Michael A, Gavin, James R, Kittles, Rick A, Zaitlen, Noah A, Wilkes, David S, Powe, Neil R, Ziv, Elad, Burchard, Esteban G

“…U.S. health inequities won’t be eliminated by abandoning the use of race and ethnicity in research and clinical practice, since these variables capture key…”
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Effect of TiO2 Addition on Mortars: Characterization and Photoactivity by Hernández-Rodríguez, M. J., Santana Rodríguez, R., Darias, R., González Díaz, O., Pérez Luzardo, J. M., Doña Rodríguez, J. M., Pulido Melián, E.

“…In this study, mortar specimens were prepared with a cement:sand:water ratio of 1:3:0.5, in accordance with standard EN196-1. Portland CEM I 52.5 R grey (G)…”
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Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients by Jin, Ying, BS, Hu, Donglei, PhD, Peterson, Edward L., PhD, Eng, Celeste, BS, Levin, Albert M., PhD, Wells, Karen, BS, Beckman, Kenneth, PhD, Kumar, Rajesh, MD, Seibold, Max A., PhD, Karungi, Gloria, MBChB, MS, Zoratti, Amanda, BA, Gaggin, John, BSN, Campbell, Janis, RN, Galanter, Joshua, MD, Chapela, Rocío, MD, Rodríguez-Santana, José R., MD, Watson, H. Geoffrey, MD, Meade, Kelley, MD, LeNoir, Michael, MD, Rodríguez-Cintrón, William, MD, Avila, Pedro C., MD, Lanfear, David E., MD, MS, Burchard, Esteban G., MD, MPH, Williams, L. Keoki, MD, MPHa

“…Background Inhaled corticosteroids (ICSs) are considered first-line treatment for persistent asthma, yet there is significant variability in treatment…”
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Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects by Torgerson, Dara G., PhD, Capurso, Daniel, BS, Ampleford, Elizabeth J., PhD, Li, Xingnan, PhD, Moore, Wendy C., MD, Gignoux, Christopher R., MS, Hu, Donglei, PhD, Eng, Celeste, BS, Mathias, Rasika A., ScD, Busse, William W., MD, Castro, Mario, MD, Erzurum, Serpil C., MD, Fitzpatrick, Anne M., PhD, Gaston, Benjamin, MD, Israel, Elliot, MD, Jarjour, Nizar N., MD, Teague, W. Gerald, MD, Wenzel, Sally E., MD, Rodríguez-Santana, José R., MD, Rodríguez-Cintrón, William, MD, Avila, Pedro C., MD, Ford, Jean G., MD, Barnes, Kathleen C., PhD, Burchard, Esteban G., MD, Howard, Timothy D., PhD, Bleecker, Eugene R., MD, Meyers, Deborah A., PhD, Cox, Nancy J., PhD, Ober, Carole, PhD, Nicolae, Dan L., PhD

“…Background Genetic variants that contribute to asthma susceptibility might be present at varying frequencies in different populations, which is an important…”
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A genome-wide association study of bronchodilator response in Latinos implicates rare variants by Drake, Katherine A., PhD, Torgerson, Dara G., PhD, Gignoux, Christopher R., MS, Galanter, Joshua M., MD, Roth, Lindsey A., MA, Huntsman, Scott, MS, Eng, Celeste, BS, Oh, Sam S., PhD, Yee, Sook Wah, PhD, Lin, Lawrence, BS, Bustamante, Carlos D., PhD, Moreno-Estrada, Andrés, MD, Sandoval, Karla, PhD, Davis, Adam, MA, MPH, Borrell, Luisa N., DDS, PhD, Farber, Harold J., MD, MSPH, Kumar, Rajesh, MD, Avila, Pedro C., MD, Brigino-Buenaventura, Emerita, MD, Chapela, Rocio, MD, Ford, Jean G., MD, LeNoir, Michael A., MD, Lurmann, Fred, MS, Meade, Kelley, MD, Serebrisky, Denise, MD, Thyne, Shannon, MD, Rodríguez-Cintrón, William, MD, Sen, Saunak, PhD, Rodríguez-Santana, José R., MD, Hernandez, Ryan D., PhD, Giacomini, Kathleen M., PhD, Burchard, Esteban G., MD, MPH

“…Background The primary rescue medication to treat acute asthma exacerbation is the short-acting β2 -adrenergic receptor agonist; however, there is variation in…”
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In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children by Neophytou, Andreas M., Oh, Sam S., Hu, Donglei, Huntsman, Scott, Eng, Celeste, Rodríguez-Santana, José R., Kumar, Rajesh, Balmes, John R., Eisen, Ellen A., Burchard, Esteban G.

“…Maternal smoking during pregnancy is a risk factor for chronic disease later in life and has been associated with variability of DNA methylation at specific…”
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Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures by Galanter, Joshua M, Gignoux, Christopher R, Oh, Sam S, Torgerson, Dara, Pino-Yanes, Maria, Thakur, Neeta, Eng, Celeste, Hu, Donglei, Huntsman, Scott, Farber, Harold J, Avila, Pedro C, Brigino-Buenaventura, Emerita, LeNoir, Michael A, Meade, Kelly, Serebrisky, Denise, Rodríguez-Cintrón, William, Kumar, Rajesh, Rodríguez-Santana, Jose R, Seibold, Max A, Borrell, Luisa N, Burchard, Esteban G, Zaitlen, Noah

“…Populations are often divided categorically into distinct racial/ethnic groups based on social rather than biological constructs. Genetic ancestry has been…”
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ORMDL3 Gene Is Associated with Asthma in Three Ethnically Diverse Populations by Galanter, Joshua, Choudhry, Shweta, Eng, Celeste, Nazario, Sylvette, Rodriguez-Santana, Jose R, Casal, Jesus, Torres-Palacios, Alfonso, Salas, Jorge, Chapela, Rocio, Watson, H. Geoffrey, Meade, Kelley, LeNoir, Michael, Rodriguez-Cintron, William, Avila, Pedro C, Burchard, Esteban Gonzalez

“…Independent replication of genetic associations in complex diseases, particularly in whole-genome association studies, is critical to confirm the association…”
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Genome‐wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations by Herrera‐Luis, Esther, Espuela‐Ortiz, Antonio, Lorenzo‐Diaz, Fabian, Keys, Kevin L., Mak, Angel C. Y., Eng, Celeste, Huntsman, Scott, Villar, Jesús, Rodriguez‐Santana, Jose R., Burchard, Esteban G., Pino‐Yanes, Maria, Genuneit, Jon

“…Background Severe asthma exacerbations are a major cause of asthma morbidity and increased healthcare costs. Several studies have shown racial and ethnic…”
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Racial/Ethnic‐Specific Differences in the Effects of Inhaled Corticosteroid Use on Bronchodilator Response in Patients With Asthma by Samedy‐Bates, Lesly‐Anne, Oh, Sam S., Nuckton, Thomas J., Elhawary, Jennifer R., White, Marquitta, Elliot, Tyronda, Zeiger, Andy M., Eng, Celeste, Salazar, Sandra, LeNoir, Michael A., Meade, Kelley, Farber, Harold J., Serebrisky, Denise, Brigino‐Buenaventura, Emerita, Rodriguez‐Cintron, William, Bibbins‐Domingo, Kirsten, Kumar, Rajesh, Thyne, Shannon, Borrell, Luisa N., Rodriguez‐Santana, José R., Pino‐Yanes, Maria, Burchard, Esteban G.

“…American Thoracic Society guidelines recommend inhaled corticosteroid (ICS) therapy, plus a short‐acting bronchodilator, in patients with persistent asthma…”
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A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth by Jiang, Yale, Forno, Erick, Han, Yueh-Ying, Xu, Zhongli, Hu, Donglei, Boutaoui, Nadia, Eng, Celeste, Acosta-Pérez, Edna, Huntsman, Scott, Colón-Semidey, Angel, Keys, Kevin L., Rodríguez-Santana, José R., Alvarez, María, Pino-Yanes, Maria, Canino, Glorisa, Chen, Wei, Burchard, Esteban G., Celedón, Juan C.

“…Latinos are heavily affected with childhood asthma. Little is known about epigenetic mechanisms of asthma in Latino youth. We conducted a meta-analysis of two…”
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The landscape of genomic imprinting across diverse adult human tissues by Baran, Yael, Subramaniam, Meena, Biton, Anne, Tukiainen, Taru, Tsang, Emily K, Rivas, Manuel A, Pirinen, Matti, Gutierrez-Arcelus, Maria, Smith, Kevin S, Kukurba, Kim R, Zhang, Rui, Eng, Celeste, Torgerson, Dara G, Urbanek, Cydney, Li, Jin Billy, Rodriguez-Santana, Jose R, Burchard, Esteban G, Seibold, Max A, MacArthur, Daniel G, Montgomery, Stephen B, Zaitlen, Noah A, Lappalainen, Tuuli

“…Genomic imprinting is an important regulatory mechanism that silences one of the parental copies of a gene. To systematically characterize this phenomenon, we…”
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Early-Life Air Pollution and Asthma Risk in Minority Children: The GALA II and SAGE II Studies by NISHIMURA, Katherine K, GALANTER, Joshua M, BRIGINO-BUENAVENTURA, Emerita, DAVIS, Adam, LENOIR, Michael A, MEADE, Kelley, RODRIGUEZ-CINTRON, William, AVILA, Pedro C, BORRELL, Luisa N, BIBBINS-DOMINGO, Kirsten, RODRIGUEZ-SANTANA, Jose R, SEN, Saunak, ROTH, Lindsey A, LURMANN, Fred, BALMES, John R, BURCHARD, Esteban G, OH, Sam S, THAKUR, Neeta, NGUYEN, Elizabeth A, THYNE, Shannon, FARBER, Harold J, SEREBRISKY, Denise, KUMAR, Rajesh

“…Air pollution is a known asthma trigger and has been associated with short-term asthma symptoms, airway inflammation, decreased lung function, and reduced…”
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Case-control admixture mapping in Latino populations enriches for known asthma-associated genes by Torgerson, Dara G., PhD, Gignoux, Christopher R., MS, Galanter, Joshua M., MD, Drake, Katherine A., MS, Roth, Lindsey A., MA, Eng, Celeste, BS, Huntsman, Scott, MS, Torres, Raul, BS, Avila, Pedro C., MD, Chapela, Rocio, MD, Ford, Jean G., MD, Rodríguez-Santana, José R., MD, Rodríguez-Cintrón, William, MD, Hernandez, Ryan D., PhD, Burchard, Esteban G., MD, MPH

“…Background Polymorphisms in more than 100 genes have been associated with asthma susceptibility, yet much of the heritability remains to be explained. Asthma…”
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The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos by Via, M., De Giacomo, A., Corvol, H., Eng, C., Seibold, M. A., Gillett, C., Galanter, J., Sen, S., Tcheurekdjian, H., Chapela, R., Rodríguez-Santana, J. R., Rodríguez-Cintrón, W., Thyne, S., Avila, P. C., Choudhry, S., González Burchard, E.

“…Summary Background Leukotrienes play an important role in allergic and inflammatory diseases, but reports on the involvement of arachidonate…”
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PAI‐1 gain‐of‐function genotype, factors increasing PAI‐1 levels, and airway obstruction: The GALA II Cohort by Sherenian, M. G., Cho, S. H., Levin, A., Min, J‐Y., Oh, S. S., Hu, D., Galanter, J., Sen, S., Huntsman, S., Eng, C., Rodriguez‐Santana, J. R., Serebrisky, D., Avila, P. C., Kalhan, R., Smith, L. J., Borrell, L. N., Seibold, M. A., Keoki Williams, L., Burchard, E. G., Kumar, R.

“…Summary Background PAI‐1 gain‐of‐function variants promote airway fibrosis and are associated with asthma and with worse lung function in subjects with asthma…”
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Childhood Obesity and Asthma Control in the GALA II and SAGE II Studies by BORRELL, Luisa N, NGUYEN, Elizabeth A, LENOIR, Michael A, LURMANN, Fred, MEADE, Kelley, SEREBRISKY, Denise, RODRIGUEZ-CINTRON, William, KUMAR, Rajesh, RODRIGUEZ-SANTANA, Jose R, THYNE, Shannon M, BURCHARD, Esteban G, ROTH, Lindsey A, OH, Sam S, TCHEUREKDJIAN, Haig, SEN, Saunak, DAVIS, Adam, FARBER, Harold J, AVILA, Pedro C, BRIGINO-BUENAVENTURA, Emerita

“…Obesity is associated with increased asthma morbidity, lower drug responsiveness to inhaled corticosteroids, and worse asthma control. However, most prior…”
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Genetic Ancestry to Improve Precision of Race/Ethnicity-based Lung Function Equations in Children by Witonsky, Jonathan, Elhawary, Jennifer R, Eng, Celeste, Rodríguez-Santana, José R, Borrell, Luisa N, Burchard, Esteban G

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Race- and Ethnicity-Based Spirometry Reference Equations: Are They Accurate for Genetically Admixed Children? by Witonsky, Jonathan, Elhawary, Jennifer R, Eng, Celeste, Rodríguez-Santana, José R, Borrell, Luisa N, Burchard, Esteban G

“…Variation in genetic ancestry among genetically admixed racial and ethnic groups may influence the fit of guideline-recommended spirometry reference equations,…”
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