Search Results - "Santacana, Marı́a"

Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation by Rodrigo, José, Alonso, David, Fernández, Ana Patricia, Serrano, Julia, Richart, Ana, López, Juan Carlos, Santacana, Marı́a, Martı́nez-Murillo, Ricardo, Bentura, Marı́a Luisa, Ghiglione, Margarita, Uttenthal, Lars Otto

“…A perfusion model of global cerebral ischemia was used for the immunohistochemical study of changes in the glutamate-nitric oxide (NO) system in the rat…”
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Distribution of adrenomedullin-like immunoreactivity in the rat central nervous system by light and electron microscopy by Serrano, Julia, Uttenthal, L.Otto, Martı́nez, Alfredo, Fernández, A.Patricia, Martı́nez de Velasco, Javier, Alonso, David, Bentura, Marı́a Luisa, Santacana, Marı́a, Gallardo, José R, Martı́nez-Murillo, Ricardo, Cuttitta, Frank, Rodrigo, José

“…Adrenomedullin is a peptide of marked vasodilator activity first isolated from human pheochromocytoma and subsequently demonstrated in other mammalian tissues…”
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Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer by Felip, Isidre, Moiola, Cristian Pablo, Megino-Luque, Cristina, Lopez-Gil, Carlos, Cabrera, Silvia, Solé-Sánchez, Sonia, Muñoz-Guardiola, Pau, Megias-Roda, Elisabet, Pérez-Montoyo, Héctor, Alfon, José, Yeste-Velasco, Marc, Santacana, María, Dolcet, Xavier, Reques, Armando, Oaknin, Ana, Rodríguez-Freixinos, Victor, Lizcano, José Miguel, Domènech, Carles, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Colas, Eva, Eritja, Nuria

“…The PI3K/AKT/mTOR pathway is frequently overactivated in endometrial cancer (EC). We assessed the efficacy of ABTL0812, a novel first-in-class molecule…”
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Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy‐mediated drug resistance in ovarian cancer cells, xenografts, and patient‐derived xenograft models by Santiago‐O’Farrill, Janice M., Weroha, S. John, Hou, Xiaonan, Oberg, Ann L., Heinzen, Ethan P., Maurer, Matthew J., Pang, Lan, Rask, Philip, Amaravadi, Ravi K., Becker, Sarah E., Romero, Ignacio, Rubio, Ma Jesús, Matias‐Guiu, Xavier, Santacana, Maria, Llombart‐Cussac, Antonio, Poveda, Andrés, Lu, Zhen, Bast, Robert C.

“…Background Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors exhibit promising activity against ovarian cancers, but their efficacy can be…”
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Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T Tumors by Mancikova Veronika, Montero-Conde, Cristina, Perales-Paton, Javier, Fernandez, Agustin, Santacana María, Jodkowska Karolina, Inglada-Píérez Lucia, Castelblanco Esmeralda, Borrego Salud, Encinas, Mario, Matias-Guiu Xavier, Fraga, Mario, Robledo, Mercedes

“…Purpose: Medullary thyroid carcinoma (MTC) is a rare disease with few genetic drivers, and the etiology specific to each known susceptibility mutation remains…”
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Biomimetic device and foreign body reaction cooperate for efficient tumour cell capture in murine advanced ovarian cancer by Alonso-Alconada, Lorena, de la Fuente, Alexandre, Santacana, María, Ferreiros, Alba, Lopez-Lopez, Rafael, Matias-Guiu, Xavier, Abal, Miguel

“…Metastasis is facilitated by the formation of pre-metastatic niches through the remodelling of the extracellular matrix (ECM) promoted by haematopoietic and…”
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CTCs‐derived xenograft development in a triple negative breast cancer case by Pereira‐Veiga, Tais, Abreu, Manuel, Robledo, Diego, Matias‐Guiu, Xavier, Santacana, María, Sánchez, Laura, Cueva, Juan, Palacios, Patricia, Abdulkader, Ihab, López‐López, Rafael, Muinelo‐Romay, Laura, Costa, Clotilde

“…Triple‐negative breast cancer (TNBC) is characterized by high rates of metastasis and no available molecular targets. CTCs derived xenografts (CDX) have…”
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Psychometric properties of the Life Orientation Test (LOT-R) and its relationship with psychological well-being and academic progress in college students by Gustems-Carnicer, Josep, Calderón, Caterina, Forn Santacana, Maria

“…The aim of this study is to analyze the dimensionality of the Spanish version of the Revised Life Orientation Test (LOT-R), to examine the relationship between…”
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Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer by Eritja, Núria, Chen, Bo-Juen, Rodríguez-Barrueco, Ruth, Santacana, Maria, Gatius, Sònia, Vidal, August, Martí, Maria Dolores, Ponce, Jordi, Bergadà, Laura, Yeramian, Andree, Encinas, Mario, Ribera, Joan, Reventós, Jaume, Boyd, Jeff, Villanueva, Alberto, Matias-Guiu, Xavier, Dolcet, Xavier, Llobet-Navàs, David

“…Targeted therapies in endometrial cancer (EC) using kinase inhibitors rarely result in complete tumor remission and are frequently challenged by the appearance…”
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Palbociclib has antitumour effects on Pten‐deficient endometrial neoplasias by Dosil, Maria Alba, Mirantes, Cristina, Eritja, Núria, Felip, Isidre, Navaridas, Raúl, Gatius, Sònia, Santacana, Maria, Colàs, Eva, Moiola, Cristian, Schoenenberger, Joan Antoni, Encinas, Mario, Garí, Eloi, Matias‐Guiu, Xavier, Dolcet, Xavier

“…PTEN is one of the most frequently mutated genes in human cancers. The frequency of PTEN alterations is particularly high in endometrial carcinomas. Loss of…”
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Optimal protocol for PTEN immunostaining; role of analytical and preanalytical variables in PTEN staining in normal and neoplastic endometrial, breast, and prostatic tissues by Maiques, Oscar, PhD student, Santacana, Maria, MsC, Valls, Joan, PhD, Pallares, Judit, MD, PhD, Mirantes, Cristina, PhD student, Gatius, Sónia, MD, García Dios, Diego Andrés, PhD, Amant, Frederic, MD, PhD, Pedersen, Hans Christian, PhD, Dolcet, Xavier, PhD, Matias-Guiu, Xavier, MD, PhD

“…Summary In some tumors, phosphatase and tensin homolog ( PTEN ) inactivation may have prognostic importance and predictive value for targeted therapies…”
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Activated leukocyte cell adhesion molecule (ALCAM) is a marker of recurrence and promotes cell migration, invasion, and metastasis in early‐stage endometrioid endometrial cancer by Devis, Laura, Moiola, Cristian P, Masia, Nuria, Martinez‐Garcia, Elena, Santacana, Maria, Stirbat, Tomita Vasilica, Brochard‐Wyart, Françoise, García, Ángel, Alameda, Francesc, Cabrera, Silvia, Palacios, Jose, Moreno‐Bueno, Gema, Abal, Miguel, Thomas, William, Dufour, Sylvie, Matias‐Guiu, Xavier, Santamaria, Anna, Reventos, Jaume, Gil‐Moreno, Antonio, Colas, Eva

“…Endometrial cancer is the most common gynaecological cancer in western countries, being the most common subtype of endometrioid tumours. Most patients are…”
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ARID1A‐deficient cells require HDAC6 for progression of endometrial carcinoma by Megino‐Luque, Cristina, Sisó, Pol, Mota‐Martorell, Natalia, Navaridas, Raúl, Rosa, Inés, Urdanibia, Izaskun, Albertí‐Valls, Manel, Santacana, Maria, Pinyol, Miquel, Bonifaci, Núria, Macià, Anna, Llobet‐Navas, David, Gatius, Sònia, Matias‐Guiu, Xavier, Eritja, Núria

“…AT‐rich interactive domain‐containing protein 1A (ARID1A) loss‐of‐function mutation accompanied by a loss of ARID1A protein expression is frequently observed…”
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Oxidative stress‐induced FAK activation contributes to uterine serous carcinoma aggressiveness by Lopez‐Mejia, Isabel C., Pijuan, Jordi, Navaridas, Raúl, Santacana, Maria, Gatius, Sònia, Velasco, Ana, Castellà, Gerard, Panosa, Anaïs, Cabiscol, Elisa, Pinyol, Miquel, Coll, Laura, Bonifaci, Núria, Peña, Laura Plata, Vidal, August, Villanueva, Alberto, Gari, Eloi, Llobet‐Navàs, David, Fajas, Lluis, Matias‐Guiu, Xavier, Yeramian, Andrée

“…Uterine serous carcinoma (USC) is an aggressive form of endometrial cancer (EC), characterized by its high propensity for metastases. In fact, while…”
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Differential Immunoexpression of BRAF/V600E, Senescence Markers, PTEN, and T-type Calcium Channels in Acquired Naevi According to their Histopathological and Dermoscopic Classification by Moreno, Sara, Maiques, Oscar, Barcelo, Carla, Romero, Marta, Santacana, Maria, Gómez, Ignacio, Cuevas, Dolors, Velasco, Ana, Vea, Alvar, Macia, Anna, Boix, Ramon, Valls, Joan, Gatius, Sonia, Canti, Carles, Matias-Guiu, Xavier, Soria, Xavier, Marti, Rosa M.

“…BRAF/V600E mutation and other cell growth/growth-control mechanisms are involved in naevogenesis and melanomagenesis. Immunoexpression of BRAF/V600E and other…”
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Immune-Dependent and Independent Antitumor Activity of GM-CSF Aberrantly Expressed by Mouse and Human Colorectal Tumors by URDINGUIO, Rocio G, FERNANDEZ, Agustin F, RODRIGO, Luis, SANTACANA, Maria, MATIAS-GUIU, Xavier, SOLDEVILLA, Beatriz, DOMINGUEZ, Gemma, BONILLA, Felix, CAL, Santiago, LOPEZ-OTIN, Carlos, FRAGA, Mario F, MONCADA-PAZOS, Angela, HUIDOBRO, Covadonga, RODRIGUEZ, Ramon M, FERRERO, Cecilia, MARTINEZ-CAMBLOR, Pablo, OBAYA, Alvaro J, BERNAL, Teresa, PARRA-BLANCO, Adolfo

“…Granulocyte-macrophage colony-stimulating factor (GM-CSF/CSF2) is a cytokine produced in the hematologic compartment that may enhance antitumor immune…”
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Changes of CD68, CD163, and PD-L1 tumor expression during high-dose-rate and pulsed-dose-rate brachytherapy for cervical cancer by Berenguer Frances, Miguel A., Linares-Galiana, Isabel, Cañas Cortés, Rut, Marín i Borrás, Susanna, Gutiérrez Miguélez, Cristina, Najjari, Dina, Slocker, Andrea, Bellobí, Cinta, Santacana, María, Pané Foix, María, Alonso, M. Henar, Navarro-Martin, Arturo, Comas Antón, Silvia, Guedea, Ferran

“…We hypothesized that radiation doses delivered with high-dose-rate (HDR) and pulsed-dose-rate (PDR) brachytherapy in patients with cervical cancer could…”
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Promoter hypermethylation and expression of sprouty 2 in endometrial carcinoma by Velasco, Ana, BSc, Pallares, Judit, MD, PhD, Santacana, Maria, BSc, Gatius, Sonia, MD, Fernandez, Melisa, MD, Domingo, Monica, Valls, Joan, PhD, Yeramian, Andree, PhD, Encinas, Mario, PhD, Dolcet, Xavier, PhD, Matias-Guiu, Xavier, MD, PhD

“…Summary Sprouty 2 is a key antagonist regulator of receptor tyrosine kinases, and downstream signaling pathways, like fibroblastic growth factor (FGF) and…”
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Usefulness of Negative and Weak–Diffuse Pattern of SDHB Immunostaining in Assessment of SDH Mutations in Paragangliomas and Pheochromocytomas by Castelblanco, Esmeralda, Santacana, Maria, Valls, Joan, de Cubas, Aguirre, Cascón, Alberto, Robledo, Mercedes, Matias-Guiu, Xavier

“…This is a confirmatory study about usefulness of SDHB and SDHA immunostaining in assessment of SDH mutations in paragangliomas and pheochromocytomas…”
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Generation and Integrated Analysis of Advanced Patient‐Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer by Devis‐Jauregui, Laura, Vidal, August, Plata‐Peña, Laura, Santacana, Maria, García‐Mulero, Sandra, Bonifaci, Nuria, Noguera‐Delgado, Eulàlia, Ruiz, Nuria, Gil, Marta, Dorca, Eduard, Llobet, Francisco J., Coll‐Iglesias, Laura, Gassner, Katja, Martinez‐Iniesta, Maria, Rodriguez‐Barrueco, Ruth, Barahona, Marc, Marti, Lola, Viñals, Francesc, Ponce, Jordi, Sanz‐Pamplona, Rebeca, Piulats, Josep M., Vivancos, Ana, Matias‐Guiu, Xavier, Villanueva, Alberto, Llobet‐Navas, David

“…Clinical management of endometrial cancer (EC) is handicapped by the limited availability of second line treatments and bona fide molecular biomarkers to…”
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