Search Results - "Santacana, M."

Molecular pathology of endometrial carcinoma: practical aspects from the diagnostic and therapeutic viewpoints by Llobet, D, Pallares, J, Yeramian, A, Santacana, M, Eritja, N, Velasco, A, Dolcet, X, Matias-Guiu, X

“…This article reviews the main molecular alterations involved in endometrial carcinoma. Five molecular features (microsatellite instability, and mutations in…”
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Immunohistochemical biomarkers are prognostic relevant in addition to the ESMO-ESGO-ESTRO risk classification in endometrial cancer by Vrede, S.W., van Weelden, W.J., Visser, N.C.M., Bulten, J., van der Putten, L.J.M., van de Vijver, K., Santacana, M., Colas, E., Gil-Moreno, A., Moiola, C.P., Mancebo, G., Krakstad, C., Trovik, J., Haldorsen, I.S., Huvila, J., Koskas, M., Weinberger, V., Bednarikova, M., Hausnerova, J., van der Wurff, A.A., Matias-Guiu, X., Amant, F., Snijders, M.P.L.M., Küsters-Vandevelde, H.V.N., Reijnen, C., Pijnenborg, J.M.A.

“…Pre-operative immunohistochemical (IHC) biomarkers are not incorporated in endometrial cancer (EC) risk classification. We aim to investigate the added…”
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The amount of preoperative endometrial tissue surface in relation to final endometrial cancer classification by Vrede, S.W., Hulsman, A.M.C., Reijnen, C., Van de Vijver, K., Colas, E., Mancebo, G., Moiola, C.P., Gil-Moreno, A., Huvila, J., Koskas, M., Weinberger, V., Minar, L., Jandakova, E., Santacana, M., Matias-Guiu, X., Amant, F., Snijders, M.P.L.M., Küsters-Vandevelde, H.V.N., Bulten, J., Pijnenborg, J.M.A.

“…To evaluate whether the amount of preoperative endometrial tissue surface is related to the degree of concordance with final low- and high-grade endometrial…”
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Genome-wide Interaction Study with Smoking for Colorectal Cancer Risk Identifies Novel Genetic Loci Related to Tumor Suppression, Inflammation, and Immune Response by Carreras-Torres, Robert, Kim, Andre E, Lin, Yi, Díez-Obrero, Virginia, Bien, Stephanie A, Qu, Conghui, Wang, Jun, Dimou, Niki, Aglago, Elom K, Albanes, Demetrius, Arndt, Volker, Baurley, James W, Berndt, Sonja I, Bézieau, Stéphane, Bishop, D Timothy, Bouras, Emmanouil, Brenner, Hermann, Budiarto, Arif, Campbell, Peter T, Casey, Graham, Chan, Andrew T, Chang-Claude, Jenny, Chen, Xuechen, Conti, David V, Dampier, Christopher H, Devall, Matthew A M, Drew, David A, Figueiredo, Jane C, Gallinger, Steven, Giles, Graham G, Gruber, Stephen B, Gsur, Andrea, Gunter, Marc J, Harrison, Tabitha A, Hidaka, Akihisa, Hoffmeister, Michael, Huyghe, Jeroen R, Jenkins, Mark A, Jordahl, Kristina M, Kawaguchi, Eric, Keku, Temitope O, Kundaje, Anshul, Le Marchand, Loic, Lewinger, Juan Pablo, Li, Li, Mahesworo, Bharuno, Morrison, John L, Murphy, Neil, Nan, Hongmei, Nassir, Rami, Newcomb, Polly A, Obón-Santacana, Mireia, Ogino, Shuji, Ose, Jennifer, Pai, Rish K, Palmer, Julie R, Papadimitriou, Nikos, Pardamean, Bens, Peoples, Anita R, Pharoah, Paul D P, Platz, Elizabeth A, Rennert, Gad, Ruiz-Narvaez, Edward, Sakoda, Lori C, Scacheri, Peter C, Schmit, Stephanie L, Schoen, Robert E, Shcherbina, Anna, Slattery, Martha L, Stern, Mariana C, Su, Yu-Ru, Tangen, Catherine M, Thomas, Duncan C, Tian, Yu, Tsilidis, Konstantinos K, Ulrich, Cornelia M, van Duijnhoven, Fränzel J B, Van Guelpen, Bethany, Visvanathan, Kala, Vodicka, Pavel, Cenggoro, Tjeng Wawan, Weinstein, Stephanie J, White, Emily, Wolk, Alicja, Woods, Michael O, Hsu, Li, Peters, Ulrike, Moreno, Victor, Gauderman, W James

“…Tobacco smoking is an established risk factor for colorectal cancer. However, genetically defined population subgroups may have increased susceptibility to…”
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Immunohistochemical analysis of T‐type calcium channels in acquired melanocytic naevi and melanoma by Maiques, O., Macià, A., Moreno, S., Barceló, C., Santacana, M., Vea, A., Herreros, J., Gatius, S., Ortega, E., Valls, J., Chen, B.J., Llobet‐Navas, D., Matias‐Guiu, X., Cantí, C., Marti, R.M.

“…Summary Background Cutaneous malignant melanoma arises from transformed melanocytes de novo or from congenital or acquired melanocytic naevi. We have recently…”
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Descriptive study of naevus involution in a series of 74 patients with atypical naevus syndrome under SIAscopy digital follow‐up by Moreno, S., Maiques, O., Gatius, S., Veà, A., Barrera, J., Barcelo, C., Santacana, M., Soria, X., Matias‐Guiu, X., Martí, R.M.

“…Background Characterization of nevi involution could help to understand the biological behaviour of melanocytic neoplasms. Objective To describe the frequency…”
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Mutation profile and clinical outcome of mixed endometrioid-serous endometrial carcinomas are different from that of pure endometrioid or serous carcinomas by Coenegrachts, L., Garcia-Dios, D. A., Depreeuw, J., Santacana, M., Gatius, S., Zikan, M., Moerman, P., Verbist, L., Lambrechts, D., Matias-Guiu, Xavier, Amant, Frédéric

“…Clinical outcome of 23 patients with mixed endometrioid and serous endometrial carcinomas (mixed EEC-SC) was compared to that of pure endometrioid (EEC) and…”
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Sprouty1 is a candidate tumor-suppressor gene in medullary thyroid carcinoma by Macià, A, Gallel, P, Vaquero, M, Gou-Fabregas, M, Santacana, M, Maliszewska, A, Robledo, M, Gardiner, J R, Basson, M A, Matias-Guiu, X, Encinas, M

“…Medullary thyroid carcinoma (MTC) is a malignancy derived from the calcitonin-producing C-cells of the thyroid gland. Oncogenic mutations of the Ret…”
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Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: results from the EPIC cohort by Ose, J, Fortner, R T, Schock, H, Peeters, P H, Onland-Moret, N C, Bueno-de-Mesquita, H B, Weiderpass, E, Gram, I T, Overvad, K, Tjonneland, A, Dossus, L, Fournier, A, Baglietto, L, Trichopoulou, A, Benetou, V, Trichopoulos, D, Boeing, H, Masala, G, Krogh, V, Matiello, A, Tumino, R, Popovic, M, Obón-Santacana, M, Larrañaga, N, Ardanaz, E, Sánchez, M-J, Menéndez, V, Chirlaque, M-D, Travis, R C, Khaw, K-T, Brändstedt, J, Idahl, A, Lundin, E, Rinaldi, S, Kuhn, E, Romieu, I, Gunter, M J, Merritt, M A, Riboli, E, Kaaks, R

“…Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk…”
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The multikinase inhibitor Sorafenib induces apoptosis and sensitises endometrial cancer cells to TRAIL by different mechanisms by Llobet, D, Eritja, N, Yeramian, A, Pallares, J, Sorolla, A, Domingo, M, Santacana, M, Gonzalez-Tallada, F.J, Matias-Guiu, X, Dolcet, X

“…Abstract Sorafenib induces apoptosis and enhances Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-induced cell killing of tumoural cells. We…”
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Formation of an olfactory glomerulus: morphological aspects of development and organization by Valverde, F, Santacana, M, Heredia, M

“…We have studied the development of olfactory nerves in the rat from their first contact with the telencephalic vesicle until the formation of glomerular…”
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Adrenomedullin expression is up-regulated by ischemia–reperfusion in the cerebral cortex of the adult rat by Serrano, J, Alonso, D, Encinas, J.M, Lopez, J.C, Fernandez, A.P, Castro-blanco, S, Fernández-Vizarra, P, Richart, A, Bentura, M.L, Santacana, M, Uttenthal, L.O, Cuttitta, F, Rodrigo, J, Martinez, A

“…Changes in the pattern of adrenomedullin expression in the rat cerebral cortex after ischemia–reperfusion were studied by light and electron microscopic…”
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Adrenomedullin in the central nervous system by Serrano, J., Alonso, D., Fernández, A.P., Encinas, J.M., López, J.C., Castro-Blanco, S., Fernández-Vizarra, P., Richart, A., Santacana, M., Uttenthal, L.O., Bentura, M.L., Martínez-Murillo, R., Martínez, A., Cuttitta, F., Rodrigo, J.

“…Adrenomedullin (AM) is a novel vasodilator peptide first purified from human pheochromocytoma by tracing its capacity to stimulate cAMP production in…”
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Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat by Uttenthal, L.O., Alonso, D., Fernández, A.P., Campbell, R.O., Moro, M.A., Leza, J.C., Lizasoain, I., Esteban, F.J., Barroso, J.B., Valderrama, R., Pedrosa, J.A., Peinado, M.A., Serrano, J., Richart, A., Bentura, M.L., Santacana, M., Martínez-Murillo, R., Rodrigo, J.

“…Neuronal and inducible nitric oxide synthase (nNOS and iNOS) and nitrotyrosine immunoreactivities were localized and semiquantitatively assessed in the…”
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Early effects of iodine deficiency on radial glial cells of the hippocampus of the rat fetus. A model of neurological cretinism by Martínez-Galán, J R, Pedraza, P, Santacana, M, Escobar del Ray, F, Morreale de Escobar, G, Ruiz-Marcos, A

“…The most severe brain damage associated with thyroid dysfunction during development is observed in neurological cretins from areas with marked iodine…”
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Coexistence of translocated cytochrome c and nitrated protein in neurons of the rat cerebral cortex after oxygen and glucose deprivation by Alonso, D, Encinas, J.M, Uttenthal, L.O, Boscá, L, Serrano, J, Fernández, A.P, Castro-Blanco, S, Santacana, M, Bentura, M.L, Richart, A, Fernández-Vizarra, P, Rodrigo, J

“…Changes in the distribution of immunoreactive cytochrome c and protein nitration were studied in the rat cerebral cortex after oxygen and glucose deprivation…”
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Persistence of early-generated neurons in the rodent subplate: assessment of cell death in neocortex during the early postnatal period by Valverde, F, Lopez-Mascaraque, L, Santacana, M, De Carlos, JA

“…In the rat, the deepest neocortical layer forms a conspicuous cell band known as layer Vlb. Cells in layer Vlb are among the first to differentiate, and it has…”
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Distribution of immunoreactivity for the adrenomedullin binding protein, complement factor H, in the rat brain by Serrano, J, Encinas, J.M, Fernández, A.P, Castro-Blanco, S, Alonso, D, Fernández-Vizarra, P, Richart, A, Bentura, M.L, Santacana, M, Cuttitta, F, Martı́nez, A, Rodrigo, J

“…Adrenomedullin is a multifunctional amidated peptide that has been found in most nuclei of the CNS, where it plays a neuromodulatory role. An adrenomedullin…”
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PD-2 Comprehensive immunophenotyping of gastric adenocarcinoma identifies an inflamed class of tumors amenable to immunotherapies by Veas, J., Piñol, M., Sorolla, M., Parisi, E., Sorolla, A., Santacana, M., Ruiz, M., Parra, G., Aracil, C., Escartin, A., Vilardell, F., Salud, A., Montal, R.

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761P A phase II trial of avelumab in combination with pegylated liposomal doxorubicin in recurrent/metastatic endometrial cancer (GEICO 70-E): analysis according to molecular classification by Piulats Rodriguez, J.M., Palacio Vazquez, I., Alarcon, J.D., Gatius, S., Marin Jimenez, J.A., Gil Martín, M., Márquez Aragonés, A., Santacana, M., Manso Sanchez, L.M., Hernando Polo, S., Ruiz, N., Matias-Guiu, X., Romeo Marin, M., Navarro Garces, V., Barbarroja, P.

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