Search Results - "Sant, Vinayak"

Graphene-based nanomaterials for drug delivery and tissue engineering by Goenka, Sumit, Sant, Vinayak, Sant, Shilpa

“…Nanomaterials offer interesting physicochemical and biological properties for biomedical applications due to their small size, large surface area and ability…”
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Block copolymer micelles: preparation, characterization and application in drug delivery by Gaucher, Geneviève, Dufresne, Marie-Hélène, Sant, Vinayak P., Kang, Ning, Maysinger, Dusica, Leroux, Jean-Christophe

“…Block copolymer micelles are generally formed by the self-assembly of either amphiphilic or oppositely charged copolymers in aqueous medium. The hydrophilic…”
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In vitro and in vivo evaluation of cerium oxide nanoparticles in respiratory syncytial virus infection by Patel, Akhil, Kosanovich, Jessica, Sansare, Sameera, Balmuri, Sricharani, Sant, Vinayak, Empey, Kerry M., Sant, Shilpa

“…Respiratory syncytial virus (RSV) is the most common cause of viral bronchiolitis among children worldwide, yet there is no vaccine for RSV disease. This study…”
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Enhancement of oral bioavailability of poorly water-soluble drugs by poly(ethylene glycol)- block-poly(alkyl acrylate- co-methacrylic acid) self-assemblies by Sant, Vinayak P., Smith, Damon, Leroux, Jean-Christophe

“…The purpose of the present study was to determine whether pH-sensitive polymeric micelles could improve the oral bioavailability of a poorly water-soluble…”
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Synthesis of Monomethoxypolyethyleneglycol—Cholesteryl Ester and Effect of its Incorporation in Liposomes by Sant, Vinayak P., Nagarsenker, Mangal S.

“…The objective of the present study was to synthesize monomethoxypolyethyleneglycol-5000 cholesteryl ester [PEG–CH] as a cost-effective substitute for…”
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Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization by Sant, Vinayak P, Smith, Damon, Leroux, Jean-Christophe

“…The objective of the present study was to synthesize novel pH-sensitive block copolymers forming supramolecular assemblies and to explore their potential as…”
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Biodegradable and biomimetic elastomeric scaffolds for tissue-engineered heart valves by Xue, Yingfei, Sant, Vinayak, Phillippi, Julie, Sant, Shilpa

“…[Display omitted] Valvular heart diseases are the third leading cause of cardiovascular disease, resulting in more than 25,000 deaths annually in the United…”
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Design and evaluation of collagen-inspired mineral-hydrogel nanocomposites for bone regeneration by Patel, Akhil, Zaky, Samer H., Schoedel, Karen, Li, Hongshuai, Sant, Vinayak, Beniash, Elia, Sfeir, Charles, Stolz, Donna B., Sant, Shilpa

“…Bone loss due to trauma and tumors remains a serious clinical concern. Due to limited availability and disease transmission risk with autografts and…”
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Carbon-based hierarchical scaffolds for myoblast differentiation: Synergy between nano-functionalization and alignment by Patel, Akhil, Mukundan, Shilpaa, Wang, Wenhu, Karumuri, Anil, Sant, Vinayak, Mukhopadhyay, Sharmila M., Sant, Shilpa

“…[Display omitted] While several scaffolds have been proposed for skeletal muscle regeneration, multiscale hierarchical scaffolds with the complexity of…”
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Semiquantitative FTIR Analysis of the Crosslinking Density of Poly(ester amide)-Based Thermoset Elastomers by Xue, Yingfei, Patel, Akhil, Sant, Vinayak, Sant, Shilpa

“…Thermoset elastomers represent a class of polymers for a wide range of biomedical applications. Crosslinking density of thermoset elastomers is considered as…”
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Valve leaflet‐inspired elastomeric scaffolds with tunable and anisotropic mechanical properties by Xue, Yingfei, Ravishankar, Prashanth, Zeballos, M. Alejandra, Sant, Vinayak, Balachandran, Kartik, Sant, Shilpa

“…Fibrous scaffolds, which can mimic the elastic and anisotropic mechanical properties of native tissues, hold great promise in recapitulating the native tissue…”
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Hierarchically aligned fibrous hydrogel films through microfluidic self‐assembly of graphene and polysaccharides by Patel, Akhil, Xue, Yingfei, Hartley, Rebecca, Sant, Vinayak, Eles, James R., Cui, Xinyan Tracy, Stolz, Donna Beer, Sant, Shilpa

“…Despite significant interest in developing extracellular matrix (ECM)‐inspired biomaterials to recreate native cell‐instructive microenvironments, the major…”
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Self‐assembly of multiscale anisotropic hydrogels through interfacial polyionic complexation by Patel, Akhil, Sant, Vinayak, Velankar, Sachin, Dutta, Mayuri, Balasubramanian, Vibishan, Sane, Piyusha, Agrawal, Vishi, Wilson, Jamir, Rohan, Lisa C., Sant, Shilpa

“…Polysaccharides are explored for various tissue engineering applications due to their inherent cytocompatibility and ability to form bulk hydrogels. However,…”
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PEGylated poly(ester amide) elastomers with tunable physico-chemical, mechanical and degradation properties by Xue, Yingfei, Patel, Akhil, Sant, Vinayak, Sant, Shilpa

“…PEGylated poly(ester amide) biodegradable thermoset elastomers largely broaden the important properties for tissue engineering application. [Display omitted]…”
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Synthesis, physico-chemical characterization, and antioxidant effect of PEGylated cerium oxide nanoparticles by Xue, Yingfei, Balmuri, Sricharani Rao, Patel, Akhil, Sant, Vinayak, Sant, Shilpa

“…Cerium oxide nanoparticles (CNPs) represent a promising class of antioxidant nanoparticles with potential therapeutic value. Due to the easily reversible…”
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Cell-Instructive Graphene-Containing Nanocomposites Induce Multinucleated Myotube Formation by Patel, Akhil, Xue, Yingfei, Mukundan, Shilpaa, Rohan, Lisa C., Sant, Vinayak, Stolz, Donna B., Sant, Shilpa

“…Myoblast differentiation is a key step in myogenesis and has long been considered to be controlled mainly by biochemical cues such as growth factors. However,…”
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Nanofibrous composite scaffolds of poly(ester amides) with tunable physicochemical and degradation properties by Mukundan, Shilpaa, Sant, Vinayak, Goenka, Sumit, Franks, Johnathan, Rohan, Lisa C., Sant, Shilpa

“…[Display omitted] •Polyester amide elastomer scaffolds mimicking extracellular matrix were fabricated.•Scaffold properties can be tuned by varying polymer…”
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PEGylated poly(ester amide) elastomer scaffolds for soft tissue engineering by Xue, Yingfei, Yatsenko, Tatyana, Patel, Akhil, Stolz, Donna Beer, Phillippi, Julie A., Sant, Vinayak, Sant, Shilpa

“…Biodegradable synthetic elastomers with tunable mechanical and physicochemical properties remain attractive materials for soft tissue engineering. We have…”
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Rational Design of a Multipurpose Bioadhesive Vaginal Film for Co-Delivery of Dapivirine and Levonorgestrel by Li, Jing, Regev, Galit, Patel, Sravan Kumar, Patton, Dorothy, Sweeney, Yvonne, Graebing, Philip, Grab, Sheila, Wang, Lin, Sant, Vinayak, Rohan, Lisa C

“…Human immunodeficiency virus (HIV) infection and unintended pregnancy, which can lead to life-threatening complications, are two major burdens for female…”
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Sterically stabilized etoposide liposomes: evaluation of antimetastatic activity and its potentiation by combination with sterically stabilized pentoxifylline liposomes in mice by Sant, Vinayak P, Nagarsenker, M S, Rao, S G Anand, Gude, Rajiv P

“…Cytotoxic activity of chemotherapeutic agents can be enhanced by site-specific delivery or by combination with other less toxic agents. In the present study,…”
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