Search Results - "Sant'Anna, Morena B"
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Crotalphine Modulates Microglia M1/M2 Phenotypes and Induces Spinal Analgesia Mediated by Opioid-Cannabinoid Systems
Published in International journal of molecular sciences (01-10-2022)“…Pain is a worldwide public health problem and its treatment is still a challenge since clinically available drugs do not completely reverse chronic painful…”
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Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice
Published in Molecular neurobiology (01-08-2019)“…Small nerve fibers that bind the isolectin B4 (IB4 + C-fibers) are a subpopulation of primary afferent neurons that are involved in nociceptive sensory…”
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Meningeal dendritic cells drive neuropathic pain through elevation of the kynurenine metabolic pathway in mice
Published in The Journal of clinical investigation (01-12-2022)“…Neuropathic pain is one of the most important clinical consequences of injury to the somatosensory system. Nevertheless, the critical pathophysiological…”
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Crotalphine Attenuates Pain and Neuroinflammation Induced by Experimental Autoimmune Encephalomyelitis in Mice
Published in Toxins (22-11-2021)“…Multiple sclerosis (MS) is a demyelinating disease of inflammatory and autoimmune origin, which induces sensory and progressive motor impairments, including…”
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Pain and Cellular Migration Induced by Bothrops jararaca Venom in Mice Selected for an Acute Inflammatory Response: Involvement of Mast Cells
Published in Frontiers in immunology (04-02-2022)“…venom (BjV) can induce mast cell degranulation. In order to investigate the role of mast cells and the interference of the host genetic background in the…”
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Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization
Published in Scientific reports (27-05-2016)“…Peripheral neuropathic pain is a consequence of an injury/disease of the peripheral nerves. The mechanisms involved in its pathophysiology are not entirely…”
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Aldehyde dehydrogenase-2 deficiency aggravates neuroinflammation, nociception, and motor impairment in a mouse model of multiple sclerosis
Published in Free radical biology & medicine (20-11-2024)“…Aldehyde dehydrogenase-2 deficiency (ALDH2∗2) found in 36 % of Han Chinese, affects approximately 8 % of the world population. ALDH2 is a mitochondrial key…”
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COVID-19 induces proatherogenic alterations in moderate to severe non-comorbid patients: A single-center observational study
Published in Blood cells, molecules, & diseases (01-12-2021)“…Patients with COVID-19 can be asymptomatic or present mild to severe symptoms, leading to respiratory and cardiovascular complications and death. Type 2…”
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