Search Results - "Sansom, Sarah E"
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MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex
Published in PloS one (06-12-2011)“…In heart failure (HF), arrhythmogenic spontaneous sarcoplasmic reticulum (SR) Ca(2+) release and afterdepolarizations in cardiac myocytes have been linked to…”
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When dyspnea is a Hickam’s Dictum
Published in IDCases (01-01-2023)“…Synchronous opportunistic infections are luckily rare in people living with HIV (PLWH) in the era of highly effective antiretroviral medications. We describe…”
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Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains
Published in The Journal of biological chemistry (08-01-2010)“…Down syndrome (DS), or Trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. Bioinformatic…”
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Genomic Update of Phenotypic Prediction Rule for Methicillin-Resistant Staphylococcus aureus (MRSA) USA300 Discloses Jail Transmission Networks with Increased Resistance
Published in Microbiology spectrum (03-09-2021)“…Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of health care-associated (HA) and community-associated (CA) infections. USA300 strains…”
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Whole-genome sequencing for neonatal intensive care unit outbreak investigations: Insights and lessons learned
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (2021)“…Infectious diseases outbreaks are a cause of significant morbidity and mortality among hospitalized patients. Infants admitted to the neonatal intensive care…”
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Longitudinal genomic surveillance of carriage and transmission of Clostridioides difficile in an intensive care unit
Published in Nature medicine (01-10-2023)“…Despite enhanced infection prevention efforts, Clostridioides difficile remains the leading cause of healthcare-associated infections in the United States…”
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Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection?
Published in International Journal of Hypertension (01-01-2010)“…Essential hypertension is a complex disorder, caused by the interplay between many genetic variants, gene-gene interactions, and environmental factors. Given…”
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Comparison of Daily Versus Admission and Discharge Surveillance Cultures for Multidrug-Resistant Organism Detection in an Intensive Care Unit
Published in The Journal of infectious diseases (16-10-2024)“…Admission and discharge screening of patients for asymptomatic gut colonization with multidrug-resistant organisms (MDROs) is a common approach to active…”
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Rapid Environmental Contamination With Candida auris and Multidrug-Resistant Bacterial Pathogens Near Colonized Patients
Published in Clinical infectious diseases (15-05-2024)“…Abstract Background Environmental contamination is suspected to play an important role in Candida auris transmission. Understanding speed and risks of…”
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Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins
Published in RNA biology (01-09-2010)“…Down syndrome (DS) or Trisomy 21 (Ts21) is caused by the presence of an extra copy of all or part of human chromosome 21 (Hsa21) and is the most frequent…”
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Trisomy-21 gene dosage overexpression of miRNAs results in the haploinsufficiency of specific target proteins
Published in RNA biology (2010)“…Down syndrome (DS) or Trisomy 21 (Ts21) is caused by the presence of an extra copy of all or part of human chromosome 21 (Hsa21) and is the most frequent…”
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Steatosis Rates by Liver Biopsy and Transient Elastography With Controlled Attenuation Parameter in Clinical Experience of Hepatitis C Virus (HCV) and Human Immunodeficiency Virus/HCV Coinfection in a Large US Hepatitis Clinic
Published in Open forum infectious diseases (01-04-2019)“…Abstract Background Steatosis contributes to liver fibrosis in hepatitis C virus (HCV) and human immunodeficiency virus (HIV)/HCV coinfection. Liver biopsy…”
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Genomic Investigation to Identify Sources of Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Healthcare Personnel in an Acute Care Hospital
Published in Open forum infectious diseases (01-11-2022)“…Identifying the source of healthcare personnel (HCP) coronavirus disease 2019 (COVID-19) is important to guide occupational safety efforts. We used a combined…”
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miR-802 regulates human angiotensin II type 1 receptor expression in intestinal epithelial C2BBe1 cells
Published in American journal of physiology: Gastrointestinal and liver physiology (01-09-2010)“…Studies have demonstrated that angiotensin II (Ang II) can regulate intestinal fluid and electrolyte transport and control intestinal wall muscular activity…”
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miRNAs got rhythm
Published in Life sciences (1973) (28-02-2011)“…Despite significant advances in treatments, cardiovascular disease (CVD) remains the leading cause of human morbidity and mortality in developed countries. The…”
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2243. Patterns of Micafungin Prescribing in the Intensive Care Unit in an Observational Retrospective Cohort
Published in Open forum infectious diseases (27-11-2023)Get full text
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2956. Increased Microbiota Alpha Diversity is Associated with Decreased Hospital Mortality in Medical Intensive Care Unit Patients
Published in Open forum infectious diseases (27-11-2023)Get full text
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