Search Results - "Sansevere, Emily"
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A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis
Published in PLoS pathogens (01-09-2021)“…Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women…”
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Journal Article -
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Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis
Published in Infection and immunity (01-06-2017)“…skin infection is a frequent and recurrent problem in children with the common inflammatory skin disease atopic dermatitis (AD). colonizes the skin of the…”
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Journal Article -
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Transposase-Mediated Excision, Conjugative Transfer, and Diversity of ICE6013 Elements in Staphylococcus aureus
Published in Journal of bacteriology (01-04-2017)“…ICE6013 represents one of two families of integrative conjugative elements (ICEs) identified in the pan-genome of the human and animal pathogen Staphylococcus…”
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Journal Article -
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Transposase-Mediated Excision, Conjugative Transfer, and Diversity of ICE 6013 Elements in Staphylococcus aureus
Published in Journal of bacteriology (15-04-2017)“…ICE represents one of two families of integrative conjugative elements (ICEs) identified in the pan-genome of the human and animal pathogen Here we…”
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Journal Article -
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The Vacuolar Ca2+ ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis
Published in mSphere (06-02-2019)“…ABSTRACTCalcium is a critically important secondary messenger of intracellular signal transduction in eukaryotes but must be maintained at low levels in the…”
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Journal Article -
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Differential requirements of protein geranylgeranylation for the virulence of human pathogenic fungi
Published in Virulence (01-01-2019)“…Protein prenylation is a crucial post-translational modification largely mediated by two heterodimeric enzyme complexes, farnesyltransferase and…”
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Journal Article -
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Staphylococci on ICE: Overlooked agents of horizontal gene transfer
Published in Mobile genetic elements (04-07-2017)“…Horizontal gene transfer plays a significant role in spreading antimicrobial resistance and virulence genes throughout the genus Staphylococcus, which includes…”
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Journal Article -
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Abstract PO1-07-01: Artificial intelligence-based prediction of Oncotype DX Score from whole slide images using human-interpretable features and breast biomarkers
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…Abstract Background The Oncotype DX Breast Recurrence Score assay (ODX) is a commonly used genomic test for patients with estrogen receptor (ER)-positive,…”
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Journal Article -
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A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis via altered secretion of candidalysin
Published in Access microbiology (17-12-2021)“…Background: Candida albicans is the primary etiological agent of vulvovaginal candidiasis (VVC) and exerts its pathogenicity through secretion of the peptide…”
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Journal Article -
10
Excision, Conjugation, and Diversity of the Integrative Conjugative Element, ICE6013, in Staphylococcus aureus
Published 01-01-2017“…Staphylococcus aureus is a leading cause of community- and hospital-acquired infections. Aggressive infections and antibiotic resistance are major clinical…”
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Dissertation -
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The Vacuolar Ca 2+ ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis
Published in mSphere (27-02-2019)“…Calcium is a critically important secondary messenger of intracellular signal transduction in eukaryotes but must be maintained at low levels in the cytoplasm…”
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Journal Article