Search Results - "Sanon, Nathalie"
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Feasibility of implantable iron oxide nanoparticles in detecting brain activity-proof of concept in a rat model
Published in Epilepsy research (01-05-2021)“…•We investigated a new method of epileptic focus detection using nanoparticles.•Nanoparticles-containing capsules were implanted over the cortex of living…”
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Early-life stress is associated with gender-based vulnerability to epileptogenesis in rat pups
Published in PloS one (03-08-2012)“…During development, the risk of developing mesial temporal lobe epilepsy (MTLE) increases when the developing brain is exposed to more than one insult in early…”
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Superparamagnetic iron oxide nanoparticles-based detection of neuronal activity
Published in Nanomedicine (01-02-2022)“…Precise detection of brain regions harboring heightened electrical activity plays a central role in the understanding and treatment of diseases such as…”
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Sex differences in the developing brain impact stress-induced epileptogenicity following hyperthermia-induced seizures
Published in Neurobiology of disease (01-12-2021)“…Febrile seizures (FS) are common, affecting 2–5% of children between the ages of 3 months and 6 years. Complex FS occur in 10% of patients with FS and are…”
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Sex-specific differences in KCC2 localisation and inhibitory synaptic transmission in the rat hippocampus
Published in Scientific reports (24-02-2022)“…Sexual differentiation of the brain is influenced by testosterone and its metabolites during the perinatal period, when many aspects of brain development,…”
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Decrease of SYNGAP1 in GABAergic cells impairs inhibitory synapse connectivity, synaptic inhibition and cognitive function
Published in Nature communications (09-11-2016)“…Haploinsufficiency of the SYNGAP1 gene, which codes for a Ras GTPase-activating protein, impairs cognition both in humans and in mice. Decrease of Syngap1 in…”
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Prolongation of Action Potential Duration and QT Interval During Epilepsy Linked to Increased Contribution of Neuronal Sodium Channels to Cardiac Late Na+ Current: Potential Mechanism for Sudden Death in Epilepsy
Published in Circulation. Arrhythmia and electrophysiology (01-08-2015)“…BACKGROUND—Arrhythmias associated with QT prolongation on the ECG often lead to sudden unexpected death in epilepsy. The mechanism causing a prolongation of…”
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Favorable adverse effect profile of brivaracetam vs levetiracetam in a preclinical model
Published in Epilepsy & behavior (01-02-2018)“…Levetiracetam (LEV), and its newer selective analog brivaracetam (BRV), are two seizure medications that share an innovative mechanism of action targeting the…”
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Humanized mouse model of Rasmussen's encephalitis supports the immune-mediated hypothesis
Published in The Journal of clinical investigation (01-05-2018)“…Rasmussen's encephalitis (RE) is a chronic inflammatory brain disorder that causes frequent seizures and unilateral hemispheric atrophy with progressive…”
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Reducing premature KCC2 expression rescues seizure susceptibility and spine morphology in atypical febrile seizures
Published in Neurobiology of disease (01-07-2016)“…Abstract Atypical febrile seizures are considered a risk factor for epilepsy onset and cognitive impairments later in life. Patients with temporal lobe…”
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Interneuron subtype specific activation of mGluR1/5 during epileptiform activity in hippocampus
Published in Epilepsia (Copenhagen) (01-08-2010)“…Summary Purpose: Specific inhibitory interneurons in area CA1 of the hippocampus, notably those located in stratum oriens–alveus (O/A‐INs), are selectively…”
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Atypical Febrile Seizures, Mesial Temporal Lobe Epilepsy, and Dual Pathology
Published in Epilepsy Research and Treatment (01-01-2012)“…Febrile seizures occurring in the neonatal period, especially when prolonged, are thought to be involved in the later development of mesial temporal lobe…”
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Short‐term Effects of Kainic Acid on CA1 Hippocampal Interneurons Differentially Vulnerable to Excitotoxicity
Published in Epilepsia (Copenhagen) (01-06-2005)“…Purpose: We sought to identify the inhibitory interneurons of the rat hippocampal CA1 region selectively vulnerable in the kainic acid (KA) model of temporal…”
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Behavior of superparamagnetic nanoparticles in regard of brain activity - a proof of concept
Published in 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (01-08-2016)“…The study of cerebral magnetic activity is very promising for the understanding and care of diseases involving impaired cerebral activity such as epilepsy. One…”
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Epilepsy Increases the Contribution of Tetrodoxin-Sensitive Channels to the Cardiac Sodium Current
Published in Biophysical journal (28-01-2014)Get full text
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Development and characterization of a novel mouse model of Rasmussen's encephalitis
Published in Journal of neuroimmunology (01-01-2014)Get full text
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Cell type-specific changes in spontaneous and minimally evoked excitatory synaptic activity in hippocampal CA1 interneurons of kainate-treated rats
Published in Epilepsy research (01-03-2006)“…The epileptiform activity in the kainic acid (KA) model of epilepsy arises from complex changes in excitation and inhibition. To assess the involvement of…”
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