COVID-19 Induced Acute Respiratory Distress Syndrome-A Multicenter Observational Study

Proportions of patients dying from the coronavirus disease-19 (COVID-19) vary between different countries. We report the characteristics; clinical course and outcome of patients requiring intensive care due to COVID-19 induced acute respiratory distress syndrome (ARDS). This is a retrospective, obse...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in medicine Vol. 7; p. 599533
Main Authors: Herrmann, Johannes, Adam, Elisabeth Hannah, Notz, Quirin, Helmer, Philipp, Sonntagbauer, Michael, Ungemach-Papenberg, Peter, Sanns, Andreas, Zausig, York, Steinfeldt, Thorsten, Torje, Iuliu, Schmid, Benedikt, Schlesinger, Tobias, Rolfes, Caroline, Reyher, Christian, Kredel, Markus, Stumpner, Jan, Brack, Alexander, Wurmb, Thomas, Gill-Schuster, Daniel, Kranke, Peter, Weismann, Dirk, Klinker, Hartwig, Heuschmann, Peter, Rücker, Viktoria, Frantz, Stefan, Ertl, Georg, Muellenbach, Ralf Michael, Mutlak, Haitham, Meybohm, Patrick, Zacharowski, Kai, Lotz, Christopher
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 18-12-2020
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Proportions of patients dying from the coronavirus disease-19 (COVID-19) vary between different countries. We report the characteristics; clinical course and outcome of patients requiring intensive care due to COVID-19 induced acute respiratory distress syndrome (ARDS). This is a retrospective, observational multicentre study in five German secondary or tertiary care hospitals. All patients consecutively admitted to the intensive care unit (ICU) in any of the participating hospitals between March 12 and May 4, 2020 with a COVID-19 induced ARDS were included. A total of 106 ICU patients were treated for COVID-19 induced ARDS, whereas severe ARDS was present in the majority of cases. Survival of ICU treatment was 65.0%. Median duration of ICU treatment was 11 days; median duration of mechanical ventilation was 9 days. The majority of ICU treated patients (75.5%) did not receive any antiviral or anti-inflammatory therapies. Venovenous (vv) ECMO was utilized in 16.3%. ICU triage with population-level decision making was not necessary at any time. Univariate analysis associated older age, diabetes mellitus or a higher SOFA score on admission with non-survival during ICU stay. A high level of care adhering to standard ARDS treatments lead to a good outcome in critically ill COVID-19 patients.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
These authors share senior authorship
Reviewed by: Jesus Rico-Feijoo, Hospital Universitario Río Hortega, Spain; Tommaso Tonetti, University of Bologna, Italy
Edited by: Jiapeng Huang, University of Louisville, United States
This article was submitted to Intensive Care Medicine and Anesthesiology, a section of the journal Frontiers in Medicine
These authors share first authorship
ISSN:2296-858X
2296-858X
DOI:10.3389/fmed.2020.599533