Search Results - "Sanna, Giuseppina"
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Antiviral Activity of Vitis vinifera Leaf Extract against SARS-CoV-2 and HSV-1
Published in Viruses (29-06-2021)“…Vitis vinifera represents an important and renowned source of compounds with significant biological activity. Wines and winery bioproducts, such as grape…”
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2
Hylin-a1: A Pan-Inhibitor against Emerging and Re-Emerging Respiratory Viruses
Published in International journal of molecular sciences (01-09-2023)“…Pandemic and epidemic outbreaks of respiratory viruses are a challenge for public health and social care system worldwide, leading to high mortality and…”
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3
Repurposing the Antibacterial Activity of the Drug Teniposide Against Gram-Positive Bacteria
Published in Cellular microbiology (01-01-2024)“…Drug repurposing is sparking considerable interest due to reduced costs and development times. The current study details the screening of teniposide, an…”
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4
Synthesis and Biological Evaluation of Novel Indole-Derived Thioureas
Published in Molecules (Basel, Switzerland) (07-10-2018)“…A series of 2-(1 -indol-3-yl)ethylthiourea derivatives were prepared by condensation of 2-(1 -indol-3-yl)ethanamine with appropriate aryl/alkylisothiocyanates…”
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5
Measles Virus Bearing Measles Inclusion Body Encephalitis-Derived Fusion Protein Is Pathogenic after Infection via the Respiratory Route
Published in Journal of virology (15-04-2019)“…A clinical isolate of measles virus (MeV) bearing a single amino acid alteration in the viral fusion protein (F; L454W) was previously identified in two…”
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6
Synthesis and Antiproliferative Effect of Halogenated Coumarin Derivatives
Published in Molecules (Basel, Switzerland) (01-12-2022)“…A series of 6- and 6,8-halocoumarin derivatives have been investigated as potential antiproliferative compounds against a panel of tumor and normal cell lines…”
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7
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative
Published in Viruses (04-01-2021)“…Enterovirus A71 (EV-A71) infection has emerged as a significant public health concern atthe global level. Epidemic events of EV-A71 have been reported…”
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8
Design of Three Residues Peptides against SARS-CoV-2 Infection
Published in Viruses (22-09-2022)“…The continuous and rapid spread of the COVID-19 pandemic has emphasized the need to seek new therapeutic and prophylactic treatments. Peptide inhibitors are a…”
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9
Exploring the Antiviral Potential of Esters of Cinnamic Acids with Quercetin
Published in Viruses (24-04-2024)“…Severe acute respiratory syndrome-related Coronavirus 2 (SARS-CoV-2) has infected more than 762 million people to date and has caused approximately 7 million…”
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10
Potent and Selective Activity against Human Immunodeficiency Virus 1 (HIV-1) of Thymelaea hirsuta Extracts
Published in Viruses (19-06-2020)“…Historically, natural products have been the most successful source of inspiration for the development of new drugs. Members of the Thymelaeaceae family have…”
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5,6-Dichloro-2-phenyl-benzotriazoles: New Potent Inhibitors of Orthohantavirus
Published in Viruses (20-01-2020)“…Orthohantaviruses, previously known as hantaviruses (family Hantaviridae, order Bunyavirales), are emerging zoonoses hosted by different rodent and insectivore…”
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Clinical outcomes after palbociclib with or without endocrine therapy in postmenopausal women with hormone receptor positive and HER2-negative metastatic breast cancer enrolled in the TREnd trial
Published in Breast cancer research : BCR (29-05-2019)“…Currently, there is limited data regarding the effectiveness of standard subsequent line therapies such as endocrine therapy, chemotherapy, or targeted agents…”
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13
Sepsis-A Retrospective Cohort Study of Bloodstream Infections
Published in Antibiotics (Basel) (28-11-2020)“…Bloodstream infections (BSIs) are among the leading causes of morbidity and mortality worldwide, among infectious diseases. Local knowledge of the main…”
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14
Biological Activities of Essential Oils from Leaves of Paramignya trimera (Oliv.) Guillaum and Limnocitrus littoralis (Miq.) Swingle
Published in Antibiotics (Basel) (24-04-2020)“…The present study aimed to determine the bioactivities of essential oils extracted from the leaves of and , including cytotoxicity, antiviral, antibacterial,…”
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15
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives
Published in Pharmaceuticals (Basel, Switzerland) (01-03-2023)“…Several human diseases are caused by enteroviruses and are currently clinically untreatable, pushing the research to identify new antivirals. A notable number…”
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EFFECT: a randomized phase II study of efficacy and impact on function of two doses of nab-paclitaxel as first-line treatment in older women with advanced breast cancer
Published in Breast cancer research : BCR (05-08-2020)“…Limited data are available regarding the use of nab-paclitaxel in older patients with breast cancer. A weekly schedule is recommended, but there is a paucity…”
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Phytochemical Compositions and Biological Activities of Essential Oils from the Leaves, Rhizomes and Whole Plant of Hornstedtia bella Škorničk
Published in Antibiotics (Basel) (18-06-2020)“…The rapid emergence of drug-resistant strains and novel viruses have motivated the search for new anti-infectious agents. In this study, the chemical…”
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18
Limonoids from Melia azedarach Fruits as Inhibitors of Flaviviruses and Mycobacterium tubercolosis
Published in PloS one (20-10-2015)“…The biological diversity of nature is the source of a wide range of bioactive molecules. The natural products, either as pure compounds or as standardized…”
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Anthraquinone Rhein Exhibits Antibacterial Activity against Staphylococcus aureus
Published in Applied sciences (01-09-2022)“…Staphylococcus aureus (S. aureus) represents an important pathogen of clinical relevance, causing a wide variety of symptoms. The broad distribution of…”
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SARS-CoV-2 Fusion Peptide Conjugated to a Tetravalent Dendrimer Selectively Inhibits Viral Infection
Published in Pharmaceutics (01-12-2023)“…Fusion is a key event for enveloped viruses, through which viral and cell membranes come into close contact. This event is mediated by viral fusion proteins,…”
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