Search Results - "Sanna, Bastiano"
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Development of Polymeric Microbubbles Targeted to Prostate-Specific Membrane Antigen as Prototype of Novel Ultrasound Contrast Agents
Published in Molecular pharmaceutics (06-06-2011)“…Ultrasound-targeted microbubbles (MBs) offer new opportunities to enhance the capabilities of diagnostic ultrasound (US) imaging to specific pathological…”
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Cdc42 is an antihypertrophic molecular switch in the mouse heart
Published in The Journal of clinical investigation (01-10-2009)“…To improve contractile function, the myocardium undergoes hypertrophic growth without myocyte proliferation in response to both pathologic and physiologic…”
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Direct and Indirect Interactions between Calcineurin-NFAT and MEK1-Extracellular Signal-Regulated Kinase 1/2 Signaling Pathways Regulate Cardiac Gene Expression and Cellular Growth
Published in Molecular and Cellular Biology (01-02-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Modulatory Calcineurin-Interacting Proteins 1 and 2 Function as Calcineurin Facilitators in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-2006)“…The calcium-activated phosphatase calcineurin is regulated by a binding cofactor known as modulatory calcineurin-interacting protein (MCIP) in yeast up through…”
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The Expression of the PDZ Protein MALS-1/Velis Is Regulated by Calcium and Calcineurin in Cerebellar Granule Cells
Published in The Journal of biological chemistry (20-12-2002)“…Activity-dependent gene expression is thought to be important in shaping neuronal development and in modifying the protein content of neurons. Ca2+ entry into…”
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836-P: Glucose-Dependent Insulin Production and Insulin-Independence in Type 1 Diabetes from Stem Cell–Derived, Fully Differentiated Islet Cells—Updated Data from the VX-880 Clinical Trial
Published in Diabetes (New York, N.Y.) (23-06-2023)“…VX-880 is an investigational allogeneic stem cell-derived, fully differentiated, pancreatic islet cell replacement therapy being evaluated in a phase 1/2…”
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259-OR: Stem Cell–Derived, Fully Differentiated Islet Cells for Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Cadaveric islet transplantation can achieve glycemic control in T1D, but cadaveric islet quantity and quality are limiting. We report the first…”
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Phase 2 Trials with Mgta-456, Single Cord Blood Units (CBU) Expanded with an Aryl Hydrocarbon Receptor (AHR) Antagonist, Demonstrate Uniform Engraftment and Rapid Hematopoietic Recovery in Patients Following Myeloablative or Non-Myeloablative Conditioning
Published in Blood (08-12-2017)“…Background. The use of umbilical cord blood (UCB) in transplant has been limited by the low number of CD34+ cells, resulting in prolonged periods of cytopenia…”
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Akt Downregulation by Flavin Oxidase–Induced ROS Generation Mediates Dose-Dependent Endothelial Cell Damage Elicited by Natural Antioxidants
Published in Toxicological sciences (01-03-2010)“…High intake of natural antioxidants (NA) from plant-derived foods and beverages is thought to provide cardiovascular benefits. The endothelium plays a pivotal…”
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The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway
Published in Archives of biochemistry and biophysics (15-07-2002)“…Imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate (NAMI-A) is a new ruthenium compound active against lung metastasis in vivo and tumor cell…”
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Prune melanoidins protect against oxidative stress and endothelial cell death
Published in Frontiers in bioscience (Elite edition) (01-06-2011)“…The health-promoting effects of fruit and vegetable consumption are thought to be due to phytochemicals contained in fresh plant material. Whether processed…”
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PKC/Raf/MEK/ERK signaling pathway modulates native-LDL-induced E2F-1 gene expression and endothelial cell proliferation
Published in Cardiovascular research (01-10-2003)“…The interactions of low-density lipoprotein (LDL) with the endothelium are thought to play a major role in the development of atherosclerosis. Due to this…”
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The Oxidative State of LDL is the Major Determinant of Anti/Prooxidant Effect of Coffee on Cu Catalysed Peroxidation
Published in The open biochemistry journal (2011)“…Antioxidants exert contrasting effect on low density lipoprotein (LDL) oxidation catalysed by metals, acting as pro-oxidants under select in vitro conditions…”
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The Oxidative State of LDL is the Major Determinant of Anti/Prooxidant Effect of Coffee on Cu2+ Catalysed Peroxidation
Published in The open biochemistry journal (16-04-2011)“…Antioxidants exert contrasting effect on low density lipoprotein (LDL) oxidation catalysed by metals, acting as pro-oxidants under select in vitro conditions…”
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NAMI-A inhibits the PMA-induced ODC gene expression in ECV304 cells: involvement of PKC/Raf/Mek/ERK signalling pathway
Published in International journal of oncology (01-08-2003)“…Imidazolium trans-imidazole dimethyl sulfoxide tetrachlororuthenate (NAMI-A) is a new compound active against lung metastasis of solid metastasizing tumours…”
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Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI‐A down regulates c‐myc gene expression and endothelial cell proliferation
Published in European journal of biochemistry (01-12-2002)“…Imidazolium trans‐imidazoledimethyl sulfoxide‐tetrachlororuthenate (NAMI‐A) is a novel ruthenium‐containing experimental antimetastatic agent. Compelling…”
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The evaluation of the oxidative state of native-LDL: three methods compared
Published in Journal of biochemical and biophysical methods (30-11-2004)“…LDL-oxidation is considered a contributing factor to the development of atherosclerotic lesions. However, to utilise the oxidative state of LDL as a marker of…”
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