Search Results - "Sankaralingam, Sowndramalingam"

Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy by Zhang, Liyan, Jaswal, Jagdip S, Ussher, John R, Sankaralingam, Sowndramalingam, Wagg, Cory, Zaugg, Michael, Lopaschuk, Gary D

“…Cardiac hypertrophy is accompanied by significant alterations in energy metabolism. Whether these changes in energy metabolism precede and contribute to the…”
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Cardiac energy metabolic alterations in pressure overload–induced left and right heart failure (2013 Grover Conference Series) by Sankaralingam, Sowndramalingam, Lopaschuk, Gary D.

“…Pressure overload of the heart, such as seen with pulmonary hypertension and/or systemic hypertension, can result in cardiac hypertrophy and the eventual…”
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Determination of potential drug–drug interactions in prescription orders dispensed in a community pharmacy setting using Micromedex® and Lexicomp®: a retrospective observational study by Abbas, Afraa, Al-Shaibi, Samaher, Sankaralingam, Sowndramalingam, Awaisu, Ahmed, Kattezhathu, Vyas S., Wongwiwatthananukit, Supakit, Owusu, Yaw B.

“…Background Community pharmacists have a role in identifying drug–drug interactions (DDIs) when processing prescription orders and dispensing medications to…”
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Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study by Alrob, Osama Abo, Sankaralingam, Sowndramalingam, Alazzam, Sayer, Nusairat, Buthaina, Qattoum, Muhammad, Nusair, Mohammad B

“…Background and Objectives: There is consensus on the negative effects of obesity on the development of heart failure. However, several studies have suggested…”
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Collaborative care model for diabetes in primary care settings in Qatar: a qualitative exploration among healthcare professionals and patients who experienced the service by Abdulrhim, Sara, Sankaralingam, Sowndramalingam, Ibrahim, Mohamed Izham Mohamed, Diab, Mohammed Issam, Hussain, Mohamed Abdelazim Mohamed, Al Raey, Hend, Ismail, Mohammed Thahir, Awaisu, Ahmed

“…Diabetes mellitus is highly prevalent and associated with huge economic burden globally. The conventional care and management of diabetes mellitus is highly…”
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Impact of pharmacist-involved collaborative care on diabetes management in a primary healthcare setting using real-world data by Abdulrhim, Sara, Awaisu, Ahmed, Ibrahim, Mohamed Izham Mohamed, Diab, Mohammad Issam, Hussain, Mohamed Abdelazim Mohamed, Al Raey, Hend, Ismail, Mohammed Thahir, Sankaralingam, Sowndramalingam

“…Background Diabetes mellitus is a complex multi-system disorder, requiring multi-disciplinary care. The conventional care model, where physicians are the sole…”
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The Impact of Obesity on the Pharmacology of Medications Used for Cardiovascular Risk Factor Control by Sankaralingam, Sowndramalingam, MBBS, PhD, Kim, Richard B., MD, Padwal, Raj S., MD, MSc

“…Abstract Most drugs are currently dosed empirically (fixed-dose) or based on total body weight. In obese patients, these dosing strategies might, in theory,…”
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Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy by Magee, Laura A., MD, Helewa, Michael, MD, Rey, Evelyne, MD, Cardew, Savannah, MD, Côté, Anne-Marie, MD, Douglas, M. Joanne, MD, Firoz, Tabassum, MD, Gibson, Paul S., MD, Gruslin A., Andrée, MD, Lange, Ian, MD, Leduc, Line, MD, Logan, Alexander G., MD, Moutquin, Jean-Marie, MD, Senikas, Vyta, MD, Smith, Graeme N, von Dadelszen, Peter, MBChB, Bainbridge, Shannon, BSc, Chen, Xi Kuam, BSc, Xu, Hairong, BSc, Hutcheon, Jennifer, J, BSc, Menzies, Jennifer, J, BSc, Sankaralingam, Sowndramalingam, BSc, Xie, Fang, BSc

“…Abstract Objective This guideline summarizes the quality of the evidence to date and provides a reasonable approach to the diagnosis, evaluation, and treatment…”
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Effect of exercise on vascular superoxide dismutase expression in high-risk pregnancy by Sankaralingam, Sowndramalingam, Jiang, Yanyan, Davidge, Sandra T, Yeo, SeonAe

“…Endothelial dysfunction of the maternal vasculature induced by pro-oxidants may contribute to the development of preeclampsia. Obesity results in vascular…”
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Restraint stress up-regulates lectin-like oxidized low-density lipoprotein receptor-1 in aorta of apolipoprotein E-deficient mice by Andersson, Irene J, Sankaralingam, Sowndramalingam, Davidge, Sandra T

“…Psychological stress is a risk factor for cardiovascular disease including atherosclerosis, but the mechanisms are unknown. The vascular lectin-like oxidized…”
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Calorie Restriction without Restricting Vitamins and Minerals Does Not Deteriorate Bones by Rahman, Md Mizanur, Sankaralingam, Sowndramalingam

“…Abstract only Calorie restriction has a number of health benefits, however is associated with reduction of bone mineral density (BMD). As calcium and vitamin D…”
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The impact of pharmacist care on diabetes outcomes in primary care settings: An umbrella review of published systematic reviews by Abdulrhim, Sara, Sankaralingam, Sowndramalingam, Ibrahim, Mohamed Izham Mohamed, Awaisu, Ahmed

“…•Pharmacists provide diverse interventions as part of collaborative diabetes care.•Evidence supports benefits of pharmacist care on diabetes outcomes in…”
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Antidiabetic drugs and their potential role in treating mild cognitive impairment and Alzheimer's disease by Alagiakrishnan, Kannayiram, Sankaralingam, Sowndramalingam, Ghosh, Mahua, Mereu, Laurie, Senior, Peter

“…The incidence of both diabetes mellitus (DM) and dementia increases with aging and the incidence of dementia are higher in people with diabetes…”
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Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling by Alrob, Osama Abo, Sankaralingam, Sowndramalingam, Ma, Cary, Wagg, Cory S, Fillmore, Natasha, Jaswal, Jagdip S, Sack, Michael N, Lehner, Richard, Gupta, Mahesh P, Michelakis, Evangelos D, Padwal, Raj S, Johnstone, David E, Sharma, Arya M, Lopaschuk, Gary D

“…Lysine acetylation is a novel post-translational pathway that regulates the activities of enzymes involved in both fatty acid and glucose metabolism. We…”
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Inhibition of STAT3 phosphorylation by curcumin partly reduces adhesion molecule expression in vascular endothelial cell by Ahn, Hee Yul, Cho, Young Suk, Sankaralingam, Sowndramalingam

“…OBJECTIVES We investigated whether curcumin, an ingredient of turmeric, can suppress the expression of intercellular adhesion molecule 1 (ICAM‐1) and vascular…”
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Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia by Sankaralingam, Sowndramalingam, Xu, Han, Davidge, Sandra T.

“…Aims Preeclampsia is a hypertensive disorder characterized by vascular oxidative stress. Decreased availability of the vasodilator nitric oxide (NO) has been…”
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RETIRED: Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy by Magee, Laura A, Helewa, Michael, Rey, Evelyne

“…This document has been archived because it contains outdated information. It should not be consulted for clinical use, but for historical research only. Please…”
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Determination of potential drug-drug interactions in prescription orders dispensed in a community pharmacy setting using Micromedex.sup.® and Lexicomp.sup.®: a retrospective observational study by Abbas, Afraa, Al-Shaibi, Samaher, Sankaralingam, Sowndramalingam, Awaisu, Ahmed, Kattezhathu, Vyas S, Wongwiwatthananukit, Supakit, Owusu, Yaw B

“…Background Community pharmacists have a role in identifying drug-drug interactions (DDIs) when processing prescription orders and dispensing medications to…”
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Lowering body weight in obese mice with diastolic heart failure improves cardiac insulin sensitivity and function: implications for the obesity paradox by Sankaralingam, Sowndramalingam, Abo Alrob, Osama, Zhang, Liyan, Jaswal, Jagdip S, Wagg, Cory S, Fukushima, Arata, Padwal, Raj S, Johnstone, David E, Sharma, Arya M, Lopaschuk, Gary D

“…Recent studies suggest improved outcomes and survival in obese heart failure patients (i.e., the obesity paradox), although obesity and heart failure…”
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Evidence of community pharmacists' response preparedness during COVID-19 public health crisis: A cross-sectional study by ElGeed, Hager, Owusu, Yaw, Abdulrhim, Sara, Awaisu, Ahmed, Kattezhathu, Vyas S, Abdulrouf, Palli Valapila, Sankaralingam, Sowndramalingam

“…Community pharmacists are often the first point of contact for the public, especially during pandemics. As outlined by the International Pharmaceutical…”
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