Search Results - "Sanjurjo, Lucía"
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AIM/CD5L: a key protein in the control of immune homeostasis and inflammatory disease
Published in Journal of leukocyte biology (01-08-2015)“…Review of involvement of CD5L protein in the modulation of inflammatory responses and its putative use as a biomarker of disease. CD5L, a soluble protein…”
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CD5L Promotes M2 Macrophage Polarization through Autophagy-Mediated Upregulation of ID3
Published in Frontiers in immunology (12-03-2018)“…CD5L (CD5 molecule-like) is a secreted glycoprotein that controls key mechanisms in inflammatory responses, with involvement in processes such as infection,…”
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CD5L is upregulated in hepatocellular carcinoma and promotes liver cancer cell proliferation and antiapoptotic responses by binding to HSPA5 (GRP78)
Published in The FASEB journal (01-07-2018)“…CD5‐like (CD5L) is a soluble scavenger cysteine‐rich protein that modulates inflammatory responses. We studied the involvement of CD5L in liver cancer…”
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Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine
Published in Theranostics (2017)“…Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases…”
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Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors
Published in Journal of controlled release (01-09-2024)“…The Kirsten Rat Sarcoma Virus (KRAS) oncoprotein, one of the most prevalent mutations in cancer, has been deemed undruggable for decades. The hypothesis of…”
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The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses
Published in Autophagy (01-01-2015)“…CD5L (CD5 molecule-like) is a secreted glycoprotein that participates in host response to bacterial infection. CD5L influences the monocyte inflammatory…”
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Galectokines: The Promiscuous Relationship between Galectins and Cytokines
Published in Biomolecules (Basel, Switzerland) (13-09-2022)“…Galectins, a family of glycan-binding proteins, are well-known for their role in shaping the immune microenvironment. They can directly affect the activity and…”
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Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights
Published in Nano research (01-10-2024)“…The current spotlight of cancer therapeutics is shifting towards personalized medicine with the widespread use of monoclonal antibodies (mAbs). Despite their…”
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The scavenger protein apoptosis inhibitor of macrophages (AIM) potentiates the antimicrobial response against Mycobacterium tuberculosis by enhancing autophagy
Published in PloS one (04-11-2013)“…Apoptosis inhibitor of macrophages (AIM), a scavenger protein secreted by tissue macrophages, is transcriptionally regulated by the nuclear receptor Liver X…”
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Chemokines modulate glycan binding and the immunoregulatory activity of galectins
Published in Communications biology (20-12-2021)“…Galectins are versatile glycan-binding proteins involved in immunomodulation. Evidence suggests that galectins can control the immunoregulatory function of…”
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New Betaproteobacterial Rhizobium Strains Able To Efficiently Nodulate Parapiptadenia rigida (Benth.) Brenan
Published in Applied and Environmental Microbiology (01-03-2012)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14
Published in Antioxidants (11-05-2023)“…Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins…”
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CD5L is a pleiotropic player in liver fibrosis controlling damage, fibrosis and immune cell content
Published in EBioMedicine (01-05-2019)“…Chronic hepatic inflammation leads to liver fibrosis, which may progress to cirrhosis, a condition with high morbidity. Our aim was to assess the as yet…”
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Macrophage CD5L is a target for cancer immunotherapy
Published in EBioMedicine (01-05-2023)“…Reprogramming of immunosuppressive tumor-associated macrophages (TAMs) presents an attractive therapeutic strategy in cancer. The aim of this study was to…”
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Human scavenger protein AIM increases foam cell formation and CD36‐mediated oxLDL uptake
Published in Journal of leukocyte biology (01-03-2014)“…Human scavenger protein AIM is involved in macrophage survival, adhesion, and foam cell formation, contributing to atherosclerosis‐related mechanisms in the…”
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Role of scavenger receptors in the pathophysiology of chronic liver diseases
Published in Critical reviews in immunology (2013)“…Scavenger receptors comprise a large family of structurally diverse proteins that are involved in many homeostatic functions. They recognize a wide range of…”
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Circulating Soluble CD36 is Similar in Type 1 and Type 2 Diabetes Mellitus versus Non-Diabetic Subjects
Published in Journal of clinical medicine (18-05-2019)“…The aim of this study was to determine whether plasma concentrations of sCD36 (soluble CD36) are associated with the presence of type 1 or type 2 diabetes…”
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The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism
Published in Cell reports (Cambridge) (31-01-2017)“…Macrophages exert potent effector functions against invading microorganisms but constitute, paradoxically, a preferential niche for many bacterial strains to…”
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The Circulating Fatty Acid Transporter Soluble CD36 Is Not Associated with Carotid Atherosclerosis in Subjects with Type 1 and Type 2 Diabetes Mellitus
Published in Journal of clinical medicine (02-06-2020)“…This study aimed to determine the association of fatty acid transporter plasma soluble cluster of differentiation 36 (sCD36) with subclinical carotid…”
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Effectiveness of Modified Vaccinia Ankara-Bavaria Nordic Vaccination in a Population at High Risk of Mpox: A Spanish Cohort Study
Published in Clinical infectious diseases (17-02-2024)“…With more than 7500 cases reported since April 2022, Spain has experienced the highest incidence of mpox in Europe. From 12 July onward, the modified vaccinia…”
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