Search Results - "Sanjay Desai"
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1
Epigenetics of malaria parasite nutrient uptake, but why?
Published in Trends in parasitology (01-08-2022)“…The conserved plasmodial surface anion channel (PSAC) mediates nutrient uptake by bloodstream malaria parasites and is an antimalarial target. This…”
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Long-term complications of critical care
Published in Critical care medicine (01-02-2011)“…OBJECTIVES:As critical care advances and intensive care unit mortality declines, the number of survivors of critical illness is increasing. These survivors…”
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3
Conditional permeabilization of the P. falciparum plasma membrane in infected cells links cation influx to reduced membrane integrity
Published in PloS one (04-04-2023)“…The intracellular human malaria parasite, Plasmodium falciparum, uses the PfATP4 cation pump to maintain Na+ and H+ homeostasis in parasite cytosol. PfATP4 is…”
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4
Why do malaria parasites increase host erythrocyte permeability?
Published in Trends in parasitology (01-03-2014)“…Highlights • Malaria parasites increase the permeability of their host erythrocyte to diverse solutes. • The plasmodial surface anion channel, as determined by…”
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Novel Ion Channel Genes in Malaria Parasites
Published in Genes (26-02-2024)“…Ion channels serve many cellular functions including ion homeostasis, volume regulation, signaling, nutrient acquisition, and developmental progression…”
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Long Head of Biceps Tendon Pathology and Results of Tenotomy in Full-Thickness Reparable Rotator Cuff Tear
Published in Arthroscopy (01-11-2017)“…To document the incidence of long head of the biceps tendon (LHBT) pathology in full-thickness reparable rotator cuff tears and report the clinical results of…”
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Medical School Admissions: Focusing on Producing a Physician Workforce that Addresses the Needs of the United States
Published in Academic medicine (01-09-2023)“…The aging population, burnout, and earlier retirement of physicians along with the static number of training positions are likely to worsen the current…”
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8
Optimized plasmid loading of human erythrocytes for Plasmodium falciparum DNA transfections
Published in International journal for parasitology (01-10-2024)“…[Display omitted] •A NanoLuc reporter allows rapid quantification of Plasmodium falciparum transfection outcome.•Optimized hypotonic lysis and resealing…”
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Promises and Pitfalls of Parasite Patch-clamp
Published in Trends in parasitology (01-05-2021)“…Protozoan parasites acquire essential ions, nutrients, and other solutes from their insect and vertebrate hosts by transmembrane uptake. For intracellular…”
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10
Proteolysis at a specific extracellular residue implicates integral membrane CLAG3 in malaria parasite nutrient channels
Published in PloS one (01-04-2014)“…The plasmodial surface anion channel mediates uptake of nutrients and other solutes into erythrocytes infected with malaria parasites. The clag3 genes of P…”
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11
In the Wake of the 2003 and 2011 Duty Hours Regulations, How Do Internal Medicine Interns Spend Their Time?
Published in Journal of general internal medicine : JGIM (01-08-2013)“…ABSTRACT BACKGROUND The 2003 and 2011 Accreditation Council for Graduate Medical Education (ACGME) common program requirements compress busy inpatient…”
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12
Ion and nutrient uptake by malaria parasite‐infected erythrocytes
Published in Cellular microbiology (01-07-2012)“…Summary Erythrocytes infected with malaria parasites have increased permeability to diverse organic and inorganic solutes. While these permeability changes…”
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13
An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasites
Published in eLife (21-02-2017)“…Malaria parasites evade immune detection by growth and replication within erythrocytes. After erythrocyte invasion, the intracellular pathogen must increase…”
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14
Arthroscopic Bankart Repair With and Without Curettage of the Glenoid Edge: A Prospective, Randomized, Controlled Study
Published in Arthroscopy (01-03-2021)“…To determine whether curettage of the cartilage on the glenoid edge in arthroscopic Bankart repair reduces the postoperative recurrence rate compared with…”
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15
Viscoelasticity as a Biomarker for High-Throughput Flow Cytometry
Published in Biophysical journal (19-11-2013)“…The mechanical properties of living cells are a label-free biophysical marker of cell viability and health; however, their use has been greatly limited by low…”
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16
Relationship of Physical Examination Technique to Associated Clinical Skills: Results from a Direct Observation Assessment
Published in The American journal of medicine (01-06-2022)“…: The purpose of this research was to use direct observation of the physical examination to elucidate the role physical examination technique plays in…”
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17
Physical Complications in Acute Lung Injury Survivors: A Two-Year Longitudinal Prospective Study
Published in Critical care medicine (01-04-2014)“…OBJECTIVE:Survivors of severe critical illness frequently develop substantial and persistent physical complications, including muscle weakness, impaired…”
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18
Complex nutrient channel phenotypes despite Mendelian inheritance in a Plasmodium falciparum genetic cross
Published in PLoS pathogens (18-02-2020)“…Malaria parasites activate a broad-selectivity ion channel on their host erythrocyte membrane to obtain essential nutrients from the bloodstream. This…”
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Effect of the 2011 vs 2003 duty hour regulation-compliant models on sleep duration, trainee education, and continuity of patient care among internal medicine house staff: a randomized trial
Published in JAMA internal medicine (22-04-2013)“…On July 1, 2011, the Accreditation Council for Graduate Medical Education implemented further restrictions of its 2003 regulations on duty hours and…”
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20
Posttraumatic stress disorder in general intensive care unit survivors: a systematic review
Published in General hospital psychiatry (01-09-2008)“…Abstract Objective Our objective was to summarize and critically review data on the prevalence of posttraumatic stress disorder (PTSD) in general intensive…”
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