Search Results - "Sani, Shabnam N"

Microdialysis-directed Intra-tumor Pharmacokinetic Modeling of Methotrexate in Mice and Humans by Alsulimani, Helal H, Kim, Jonghan, Sani, Shabnam N

“…To develop a quantitative pharmacokinetic model to characterize the disposition of methotrexate (MTX) at tumor site in tumor-bearing mice and to predict MTX…”
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effects of drug transporter inhibitors on the pharmacokinetics and tissue distribution of methotrexate in normal and tumor-bearing mice: a microdialysis study by Sani, Shabnam N, Henry, Katherine, Böhlke, Mark, Kim, Jonghan, Stricker-Krongrad, Alain, Maher, Timothy J

“…Purpose To examine methotrexate (MTX) tumor delivery in a mouse model using an in vivo microdialysis technique and to characterize the impact of prior…”
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Kinetic Analysis of Drug Release from Compounded Slow-release Capsules of Liothyronine Sodium (T3) by Bakhteyar, Hamid, Cassone, Clayton, Kohan, Hamed Gilzad, Sani, Shabnam N

“…The purpose of this study was to formulate extemporaneously compounded Liothyronine Sodium (T3) slow-release capsules and to evaluate their in vitro drug…”
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Effect of microfluidization parameters on the physical properties of PEG-PLGA nanoparticles prepared using high pressure microfluidization by Sani, Shabnam N., Das, Nandita G., Das, Sudip K.

“…The objective of this work was to develop uniformly distributed poly(ethylene glycol) grafted poly(lactide-co-glycolide) (PEG-PLGA) nanoparticles of mean size…”
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Calcitriol Reverses Induced Expression of Efflux Proteins and Potentiates Cytotoxic Activity of Gemcitabine in Capan-2 Pancreatic Cancer Cells by Gilzad-Kohan, Hamed, Sani, Shabnam, Boroujerdi, Mehdi

“…Efflux and influx proteins play a major role in chemo-resistance by affecting the net cellular uptake of anti-cancer drugs. Hence, alteration of the efflux and…”
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Microdialysis-directed Intra-tumor Pharmacokinetic Modeling of Methotrexate in Mice and Humans by Alsulimani, Helal H, Kim, Jonghan, Sani, Shabnam N

“…PURPOSETo develop a quantitative pharmacokinetic model to characterize the disposition of methotrexate (MTX) at tumor site in tumor-bearing mice and to predict…”
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Application of microdialysis to characterize drug disposition in pharmacokinetic studies: The case of methotrexate by Sani, Shabnam N

“…Despite many chemotherapeutic successes in recent years against hematological cancers, anticancer drugs have had a more limited impact on solid tumors…”
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Application of microdialysis to characterize drug disposition in pharmacokinetic studies: The case of methotrexate by Sani, Shabnam N

“…Despite many chemotherapeutic successes in recent years against hematological cancers, anticancer drugs have had a more limited impact on solid tumors…”
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A multiplexed optical micro-impedance biosensor array for quantitaitive cancer drug assays by Rosenberger, Erin E., English, Anthony E., Bose, Diptiman D., Sani, Shabnam N., Moy, Alan B.

“…Optically based assays have traditionally been used to quantify cancer cell proliferation and cytotoxicity in response to chemotherapeutic agents. Cellular…”
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Three dimensional spheroidal cell bioreactors for multiplexed cancer drug testing by Marshall, Gina M., English, Anthony E., Bose, Diptiman D., Sani, Shabnam N., Moy, Alan B.

“…In vitro drug testing utilizing live cancer cell cultures has enormous potential in drug discovery and personalized medicine. Cancer grows as heterogeneous…”
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Optically thin cellular micro-impedance electrode design optimization by Donovan, Ryan A., English, Anthony E., Bose, Diptiman D., Sani, Shabnam N., Moy, Alan B.

“…Optically thin micro-impedance electrodes have the potential to simultaneously provide optical microscopy measurements with electrical impedance data. Most…”
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A microfluidic biosensor array for endothelial and cancer cell co-culture interaction studies by Amaral, Katey G., English, Anthony E., Bose, Diptiman D., Sani, Shabnam N., Moy, Alan B.

“…Understanding the interaction between cancer and endothelial cells is a key element to more effective chemotherapeutics. A microfluidic cellular co-culture…”
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A low cost environmental chamber for multiplexed cancer biosensor arrays by Schaeffer, Michael C., English, Anthony E., Bose, Diptiman D., Sani, Shabnam N., Moy, Alan B.

“…A low cost environmental chamber for supporting multiplexed live cell diagnostic and therapeutic testing is presented. The chamber is designed to be compatible…”
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