Search Results - "Sanguino, A"
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MYH10 activation rescues contractile defects in arrhythmogenic cardiomyopathy (ACM)
Published in Nature communications (13-10-2023)“…The most prevalent genetic form of inherited arrhythmogenic cardiomyopathy (ACM) is caused by mutations in desmosomal plakophilin-2 ( PKP2 ). By studying…”
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Correction: Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver
Published in Oncogene (04-06-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Sirt4 Modulates Oxidative Metabolism and Sensitivity to Rapamycin Through Species-Dependent Phenotypes in Drosophila mtDNA Haplotypes
Published in G3 : genes - genomes - genetics (01-05-2020)“…The endosymbiotic theory proposes that eukaryotes evolved from the symbiotic relationship between anaerobic (host) and aerobic prokaryotes. Through iterative…”
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Assortative mating by aggressiveness type in orb weaving spiders
Published in Behavioral ecology (01-07-2013)“…Lay summary One of the most difficult questions in personality research is how personalities are maintained. Our study of bridge spiders revealed assortative…”
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PolicyCLOUD: A prototype of a cloud serverless ecosystem for policy analytics
Published in Data & Policy (01-01-2022)“…We present PolicyCLOUD: a prototype for an extensible serverless cloud-based system that supports evidence-based elaboration and analysis of policies…”
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Design Principles as a Guide for Metabolic Engineering
Published in Chemie ingenieur technik (01-09-2016)Get full text
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Immune cells from patients with psoriasis are defective in inducing indoleamine 2,3‐dioxygenase expression in response to inflammatory stimuli
Published in British journal of dermatology (1951) (01-03-2017)“…Summary Background Indoleamine 2,3‐dioxygenase (IDO) is an inducible enzyme that suppresses the immune response. The role of IDO as a negative regulator of…”
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Application of theoretical methods to increase succinate production in engineered strains
Published in Bioprocess and biosystems engineering (01-04-2017)“…Computational methods have enabled the discovery of non-intuitive strategies to enhance the production of a variety of target molecules. In the case of…”
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Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver
Published in Oncogene (04-12-2008)“…During development inhibitor of DNA-bind-2 (Id2) regulates proliferation and differentiation. Id2 expression has been detected in cancer cells, yet its…”
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Genetic diversity among Puccinia melanocephala isolates from Brazil assessed using simple sequence repeat markers
Published in Genetics and molecular research (26-09-2014)“…Brown rust (causal agent Puccinia melanocephala) is an important sugarcane disease that is responsible for large losses in yield worldwide. Despite its…”
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The evolution of synapse models--from numbers to networks to spaces
Published in Pharmacopsychiatry (01-05-2010)“…We review the evolution of synapse models over the last sixty-five years in terms of the changing paradigms: initially, the synapse was modelled only as part…”
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Tropical Achilles Tendinopathy: Sea Urchin Spine Injury
Published in Journal of the American Podiatric Medical Association (01-07-2022)“…Sea urchin spine injuries have been reported in the hand and foot, but there are no published cases in the Achilles tendon. We report an unusual case of…”
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Enhancing anti-angiogenic therapy by blocking focal adhesion kinase
Published in Gynecologic oncology (01-11-2011)Get full text
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Prevalence of rapidly progressive osteoarthritis of the hip following intra‐articular steroid injections
Published in PM & R (01-03-2023)“…Introduction Numerous studies have indicated that intra‐articular steroid injections to the hip are beneficial for short‐term pain relief. However, recent…”
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Occult Morel-Lavallee Lesion Within the Superior Gluteal Region in a Collegiate Lacrosse Player
Published in American journal of physical medicine & rehabilitation (01-09-2020)Get full text
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Hybrid modeling in computational neuropsychiatry
Published in Pharmacopsychiatry (01-09-2008)“…The aim of building mathematical models is to provide a formal structure to explain the behaviour of a whole in terms of its parts. In the particular case of…”
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Concept maps and canonical models in neuropsychiatry
Published in Pharmacopsychiatry (01-05-2009)“…Most bioscientists engage in informal modelling in their research and explicitly document this activity's results in diagrams or "concept maps". While…”
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Optimization of Tryptophan Production in Bacteria. Design of a Strategy for Genetic Manipulation of the Tryptophan Operon for Tryptophan Flux Maximization
Published in Biotechnology progress (2000)“…In the present work we have applied the indirect optimization method (Torres, N. V. et al.Biotechnol. Bioeng.1996, 49, 247–258) to the maximization of…”
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