Search Results - "Sangthong, Padchanee"
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Synthesis and biological evaluation of imidazolium conjugated with dimethylcardamonin (DMC) as a novel potential agent against MDA-MB-231 triple-negative breast cancer cells
Published in Biomedicine & pharmacotherapy (01-09-2024)“…A new imidazolium ionic liquid (IL) halide conjugated with dimethylcardamonin (DMC, 1), namely [Bbim]Br-DMC (3), was synthesised to improve the biological…”
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Effects of 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone from Syzygium nervosum Seeds on Antiproliferative, DNA Damage, Cell Cycle Arrest, and Apoptosis in Human Cervical Cancer Cell Lines
Published in Molecules (Basel, Switzerland) (09-02-2022)“…2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone (DMC), a natural product derived from A. Cunn. ex DC., was investigated for its inhibitory activities against…”
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Purification and characterization of crude fructooligosaccharides extracted from red onion (Allium cepa var. viviparum) by yeast treatment
Published in Microbial cell factories (10-01-2024)“…Yeast treatment has been used for purification of fructooligosaccharides (FOSs). However, the main drawback of this approach is that yeast can only partially…”
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A new portable toluidine blue/aptamer complex-on-polyethyleneimine-coated gold nanoparticles-based sensor for label-free electrochemical detection of alpha-fetoprotein
Published in Frontiers in bioengineering and biotechnology (22-05-2023)“…The quantification of alpha-fetoprotein (AFP) as a potential liver cancer biomarker which is generally found in ultratrace level is of significance in…”
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Nucleotide sequence analysis of mitochondrial DNA hypervariable region II and inter HVR in Thais
Published in Australian journal of forensic sciences (04-03-2021)“…In this study, the nucleotide sequences of the mitochondrial DNA hypervariable region II (HVRII) and inter HVR in the Thai population were investigated. Buccal…”
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Electrosprayed Nanoparticles Containing Mangiferin-Rich Extract from Mango Leaves for Cosmeceutical Application
Published in Nanomaterials (Basel, Switzerland) (01-11-2023)“…Mango (Mangifera indica L.) is one of the most economically important fruits in Thailand. Mango has been used as a traditional medicine because it possesses…”
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Pentagalloyl Glucose and Cisplatin Combination Treatment Exhibits a Synergistic Anticancer Effect in 2D and 3D Models of Head and Neck Carcinoma
Published in Pharmaceuticals (Basel, Switzerland) (04-07-2022)“…Although cisplatin is a first-line chemotherapy drug for head and neck squamous cell carcinoma (HNSCC), its therapeutic efficacy is limited owing to serious…”
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Pentagalloyl Glucose-Targeted Inhibition of P-Glycoprotein and Re-Sensitization of Multidrug-Resistant Leukemic Cells (K562/ADR) to Doxorubicin: In Silico and Functional Studies
Published in Pharmaceuticals (Basel, Switzerland) (22-08-2023)“…Combining phytochemicals with chemotherapeutic drugs has demonstrated the potential to surmount drug resistance. In this paper, we explore the efficacy of…”
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A radiosensitizer, gallotannin-rich extract from Bouea macrophylla seeds, inhibits radiation-induced epithelial-mesenchymal transition in breast cancer cells
Published in BMC complementary and alternative medicine (03-07-2021)“…Background Radioresistance can pose a significant obstacle to the effective treatment of breast cancers. Epithelial-mesenchymal transition (EMT) is a critical…”
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Nucleotide sequence analysis of the hypervariable region III of mitochondrial DNA in Thais
Published in Journal of forensic and legal medicine (01-07-2016)“…Abstract This study analyzed the nucleotide sequences of the hypervariable region III (HVRIII) of mitochondrial DNA in Thai individuals. Buccal swab samples…”
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Sequence analysis of mitochondrial DNA hypervariable region I in Thai individuals
Published in Australian journal of forensic sciences (03-07-2015)“…Nucleotide sequence analysis of hypervariable region I (HVRI) in human mitochondrial DNA (mtDNA) was investigated in 100 unrelated Thai individuals. A total of…”
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A label-free immunosensor for the detection of a new lung cancer biomarker, GM2 activator protein, using a phosphomolybdic acid/polyethyleneimine coated gold nanoparticle composite
Published in Analyst (London) (07-04-2021)“…In this work, we report, for the first time, the construction of a label-free electrochemical immunosensor for highly sensitive detection of a new lung cancer…”
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Simultaneous immunodetection of multiple cervical cancer biomarkers based on a signal-amplifying redox probes/polyethyleneimine-coated gold nanoparticles/2D tungsten disulfide/graphene oxide nanocomposite platform
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-12-2024)“…[Display omitted] •Highly electroreactive PEI-AuNPs/2D WS2/graphene oxide nanocomposite is developed.•Label-free immunosensor detects three clinical cervical…”
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Discovery of Natural Bisbenzylisoquinoline Analogs from the Library of Thai Traditional Plants as SARS-CoV‑2 3CLPro Inhibitors: In Silico Molecular Docking, Molecular Dynamics, and In Vitro Enzymatic Activity
Published in Journal of chemical information and modeling (10-04-2023)“…The emergence of SARS-CoV-2 in December 2019 has become a global issue due to the continuous upsurge in patients and the lack of drug efficacy for treatment…”
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2′,4′-Dihydroxy-6′‑methoxy-3′,5′-dimethylchalcone and its amino acid-conjugated derivatives induce G0/G1 cell cycle arrest and apoptosis via BAX/BCL2 ratio upregulation and in silico insight in SiHa cell lines
Published in European journal of pharmaceutical sciences (01-05-2023)“…•4′-O-(L-alanylated) DMC (3a) showed higher antiproliferative activity in human cervical cancer cell lines (C-33A, HeLa and SiHa).•SiHa cells treatment with…”
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Iron (III)-Quercetin Complex: Synthesis, Physicochemical Characterization, and MRI Cell Tracking toward Potential Applications in Regenerative Medicine
Published in Contrast media and molecular imaging (2020)“…In cell therapy, contrast agents T1 and T2 are both needed for the labeling and tracking of transplanted stem cells over extended periods of time through…”
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Potential of electro-sprayed purified mangiferin nanoparticles for anti-aging cosmetic applications
Published in RSC advances (30-11-2023)“…The fabrication of mangiferin nanoparticles using an electrospraying technique is a new and promising method for developing nanoparticles with higher…”
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Pentagalloyl Glucose- and Ethyl Gallate-Rich Extract from Maprang Seeds Induce Apoptosis in MCF-7 Breast Cancer Cells through Mitochondria-Mediated Pathway
Published in Evidence-based complementary and alternative medicine (2020)“…Bouea macrophylla Griffith, locally known as maprang, has important economic value as a Thai fruit tree. The maprang seed extract (MPSE) has been shown to…”
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Discovery of Natural Bisbenzylisoquinoline Analogs from the Library of Thai Traditional Plants as SARS-CoV-2 3CL Pro Inhibitors: In Silico Molecular Docking, Molecular Dynamics, and In Vitro Enzymatic Activity
Published in Journal of chemical information and modeling (10-04-2023)“…The emergence of SARS-CoV-2 in December 2019 has become a global issue due to the continuous upsurge in patients and the lack of drug efficacy for treatment…”
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Inhibitory Activity of Flavonoid Scaffolds on SARS-CoV‑2 3CLpro: Insights from the Computational and Experimental Investigations
Published in Journal of chemical information and modeling (12-02-2024)“…The emergence of the COVID-19 situation has become a global issue due to the lack of effective antiviral drugs for treatment. Flavonoids are a class of plant…”
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