Search Results - "Sanghavi, Maitri"

Physiologically Based Pharmacokinetics Modeling in Biopharmaceutics: Case Studies for Establishing the Bioequivalence Safe Space for Innovator and Generic Drugs by Wu, Di, Sanghavi, Maitri, Kollipara, Sivacharan, Ahmed, Tausif, Saini, Anuj K, Heimbach, Tycho

“…For successful oral drug development, defining a bioequivalence (BE) safe space is critical for the identification of newer bioequivalent formulations or for…”
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Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: Role of epigenetic histone modifications by Tikoo, Kulbhushan, Patel, Gaurang, Kumar, Sandeep, Karpe, Pinakin Arun, Sanghavi, Maitri, Malek, Vajir, Srinivasan, K.

“…Growing body of evidence points out the crucial role of ACE2 in preventing atherosclerosis. However, data on how atherosclerosis affects ACE2 expression in…”
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Role of Physiologically Based Biopharmaceutics Modeling (PBBM) in Fed Bioequivalence Study Waivers: Regulatory Outlook, Case Studies and Future Perspectives by Kollipara, Sivacharan, Martins, Frederico S, Sanghavi, Maitri, Santos, Gustavo Mendes Lima, Saini, Anuj, Ahmed, Tausif

“…Over the past few decades, physiologically based biopharmaceutics modeling (PBBM) has demonstrated its utility in both new drug and generic product…”
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NFAT inhibitor tributylhexadecylphosphoniumbromide, ameliorates high fructose induced insulin resistance and nephropathy by Sanghavi, Maitri, Vajir, Malek, Kumar, Sandeep, Tikoo, Kulbhushan

“…High fructose diet (HFrD)-induced insulin resistance (IR) has been reported to be associated with an increase in albuminuria, glomerular hypertrophy and…”
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PBBM Considerations for Base Models, Model Validation, and Application Steps: Workshop Summary Report by Heimbach, Tycho, Musuamba Tshinanu, Flora, Raines, Kimberly, Borges, Luiza, Kijima, Shinichi, Malamatari, Maria, Moody, Rebecca, Veerasingham, Shereeni, Seo, Paul, Turner, David, Fang, Lanyan, Stillhart, Cordula, Bransford, Philip, Ren, Xiaojun, Patel, Nikunjkumar, Sperry, David, Chen, Hansong, Rostami-Hodjegan, Amin, Lukacova, Viera, Sun, Duxin, Nguefack, Jean-Flaubert, Carducci, Tessa, Grimstein, Manuela, Pepin, Xavier, Jamei, Masoud, Stamatopoulos, Konstantinos, Li, Min, Sanghavi, Maitri, Tannergren, Christer, Mandula, Haritha, Zhao, Zhuojun, Ju, Tzuchi Rob, Wagner, Christian, Arora, Sumit, Wang, Michael, Rullo, Gregory, Mitra, Amitava, Kollipara, Sivacharan, Chirumamilla, Siri Kalyan, Polli, James E., Mackie, Claire

“…The proceedings from the 30th August 2023 (Day 2) of the workshop “Physiologically Based Biopharmaceutics Models (PBBM) Best Practices for Drug Product…”
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