Search Results - "Sanger, T M"

Negative symptoms: a path analytic approach to a double-blind, placebo- and haloperidol-controlled clinical trial with olanzapine by TOLLEFSON, G. D, SANGER, T. M

“…OBJECTIVE: The authors investigated whether primary negative symptoms of schizophrenia are enduring or treatment-responsive. METHODS: Previously, a…”
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Olanzapine Versus Haloperidol Treatment in First-Episode Psychosis by Sanger, Todd M., Lieberman, Jeffery A., Tohen, Mauricio, Grundy, Starr, Beasley, Jr, Charles, Tollefson, Gary D.

“…OBJECTIVE: It has been hypothesized that the morbidity and mortality associated with schizophrenia can be prevented by providing effective treatment during the…”
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Long-term olanzapine therapy in the treatment of bipolar I disorder : An open-label continuation phase study by SANGER, Todd M, GRUNDY, Starr L, GIBSON, P. Joseph, NAMJOSHI, Madhav A, GREANEY, Michael G, TOHEN, Mauricio F

“…Olanzapine has demonstrated efficacy in the treatment of acute mania in 2 double-blind, placebo-controlled trials. We describe the results of the open-label…”
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A Double-Blind, Controlled Comparison of the Novel Antipsychotic Olanzapine versus Haloperidol or Placebo on Anxious and Depressive Symptoms Accompanying Schizophrenia by Tollefson, Gary D., Sanger, Todd M., Beasley, Charles M., Tran, Pierre V.

“…Background: Depressive symptoms are a common feature of schizophrenia and may represent a core part of the illness. Where present, it has been associated with…”
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Anxious–depressive symptoms in schizophrenia: a new treatment target for pharmacotherapy? by Tollefson, Gary D., Sanger, Todd M.

“…Schizophrenia patients frequently manifest concurrent anxiety and depressive symptoms. Such features exhibit prognostic relevance (i.e. patient morbidity and…”
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Olanzapine Versus Placebo in the Treatment of Acute Mania by Tohen, Mauricio, Sanger, Todd M., McElroy, Susan L., Tollefson, Gary D., Chengappa, K.N. Roy, Daniel, David G., Petty, Frederick, Centorrino, Franca, Wang, Richard, Grundy, Starr L., Greaney, Michael G., Jacobs, Thomas G., David, Stacy R., Toma, Verna, The Olanzapine HGEH Study Group

“…OBJECTIVE: The primary intent of this study was to compare the efficacy and safety of olanzapine and placebo in the treatment of acute mania. METHOD: The…”
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Long-term antidepressant efficacy and safety of olanzapine/fluoxetine combination: A 76-week open-label study by CORYA, Sara A, ANDERSEN, Scott W, DETKE, Holland C, KELLY, Linda S, VAN CAMPEN, Luann E, SANGER, Todd M, WILLIAMSON, Douglas J, DUBE, Sanjay

“…The olanzapine/fluoxetine combination has demonstrated effectiveness in treatment-resistant depression (TRD). Although this combination is being used by…”
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Response to placebo among bipolar I disorder patients experiencing their first manic episode by Chengappa, Kn Roy, Tohen, Mauricio, Levine, Joseph, Jacobs, Thomas, Thase, Michael E, Sanger, Todd M, Kupfer, David J

“…Background: The first episode of an illness may respond differently to any treatment compared to multiple episodes of the same illness. This study details the…”
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Depressive Signs and Symptoms in Schizophrenia: A Prospective Blinded Trial of Olanzapine and Haloperidol by Tollefson, Gary D, Sanger, Todd M, Lu, Yili, Thieme, Martha E

“…BACKGROUND Depressive signs and symptoms during the course of schizophrenia are common and have been associated with impaired recovery and a higher risk of…”
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Olanzapine versus haloperidol in the treatment of schizoaffective disorder. Acute and long-term therapy by Tran, P V, Tollefson, G D, Sanger, T M, Lu, Y, Berg, P H, Beasley, Jr, C M

“…The effectiveness of antipsychotic monotherapy in schizoaffective disorder is limited, and further constrained by safety concerns. We aimed to compare the…”
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Economic, clinical, and quality-of-life outcomes associated with olanzapine treatment in mania: Results from a randomized controlled trial by Namjoshi, Madhav A, Rajamannar, Gopalan, Jacobs, Thomas, Sanger, Todd M, Risser, Richard, Tohen, Mauricio F, Breier, Alan, Keck, Paul E

“…Introduction: The objectives of this study were to determine the economic, clinical, and quality-of-life outcomes associated with olanzapine treatment in…”
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Olanzapine versus placebo in the treatment of acute mania. Olanzapine HGEH Study Group by Tohen, M, Sanger, T M, McElroy, S L, Tollefson, G D, Chengappa, K N, Daniel, D G, Petty, F, Centorrino, F, Wang, R, Grundy, S L, Greaney, M G, Jacobs, T G, David, S R, Toma, V

“…The primary intent of this study was to compare the efficacy and safety of olanzapine and placebo in the treatment of acute mania. The design involved a…”
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Olanzapine/fluoxetine combination for treatment-resistant depression : A controlled study of SSRI and nortriptyline resistance by SHELTON, Richard C, WILLIAMSON, Douglas J, CORYA, Sara A, SANGER, Todd M, VAN CAMPEN, Luann E, CASE, Michael, BRIGGS, Susan D, TOLLEFSON, Gary D

“…This 8-week, double-blind, multicenter study was undertaken to replicate, in a larger sample of patients with treatment-resistant major depressive disorder…”
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Comparative Effect of Atypical and Conventional Antipsychotic Drugs on Neurocognition in First-Episode Psychosis: A Randomized, Double-Blind Trial of Olanzapine Versus Low Doses of Haloperidol by Keefe, Richard S.E., Seidman, Larry J., Christensen, Bruce K., Hamer, Robert M., Sharma, Tonmoy, Sitskoorn, Margriet M., Lewine, Richard R.J., Yurgelun-Todd, Deborah A., Gur, Ruben C., Tohen, Mauricio, Tollefson, Gary D., Sanger, Todd M., Lieberman, Jeffrey A.

“…OBJECTIVE: The effect of antipsychotic medication on neurocognitive function remains controversial, especially since most previous work has compared the…”
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Assessing and interpreting treatment effects in longitudinal clinical trials with missing data by Mallinckrodt, Craig H, Sanger, Todd M, Dubé, Sanjay, DeBrota, David J, Molenberghs, Geert, Carroll, Raymond J, Potter, William Z, Tollefson, Gary D

“…Treatment effects are often evaluated by comparing change over time in outcome measures; however, valid analyses of longitudinal data can be problematic,…”
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Long-Term Neurocognitive Effects of Olanzapine or Low-Dose Haloperidol in First-Episode Psychosis by Keefe, Richard S.E., Seidman, Larry J., Christensen, Bruce K., Hamer, Robert M., Sharma, Tonmoy, Sitskoorn, Margriet M., Rock, Stephanie L., Woolson, Sandra, Tohen, Mauricio, Tollefson, Gary D., Sanger, Todd M., Lieberman, Jeffrey A.

“…Neurocognitive deficits are severe in first-episode psychosis. Patients ( N = 263) with first-episode psychosis (schizophrenia, schizoaffective, or…”
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A double-blind, randomized study of olanzapine and olanzapine/fluoxetine combination for major depression with psychotic features by ROTHSCHILD, Anthony J, WILLIAMSON, Douglas J, TOHEN, Mauricio F, SCHATZBERG, Alan, ANDERSEN, Scott W, VAN CAMPEN, Luann E, SANGER, Todd M, TOLLEFSON, Gary D

“…The purpose of this study was to compare the efficacy and safety of olanzapine (OLZ) monotherapy and an olanzapine/fluoxetine combination (OFC) with placebo…”
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Olanzapine in the acute treatment of bipolar I disorder with a history of rapid cycling by Sanger, Todd M., Tohen, Mauricio, Vieta, Eduard, Dunner, David L., Bowden, Charles L., Calabrese, Joseph R., Feldman, Peter D., Jacobs, Thomas G., Breier, Alan

“…Background: A substantial proportion of patients with bipolar disorder are characterized by a rapidly cycling course and are particularly resistant to…”
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Changes in Health-Related Quality of Life Associated with Olanzapine Treatment in Patients with Bipolar Disorder by M. A. Namjoshi, Rajamannar, G., T. G. Jacobs, T. M. Sanger, Gannon, K. S., M. F. Tohen, Breier, A.

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Olanzapine for Primary Negative Symptoms by Licht, Rasmus W.

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