Search Results - "Sangeeta Devi, Y"
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Reproductive actions of prolactin mediated through short and long receptor isoforms
Published in Molecular and cellular endocrinology (25-01-2014)“…•Independent signaling pathways of short form of prolactin receptor are proposed.•Prolactin is important but not essential for follicular development.•An…”
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Inhibition of IL-6 signaling pathway by curcumin in uterine decidual cells
Published in PloS one (11-05-2015)“…IL-6 is a multifunctional pro-inflammatory cytokine and has been implicated in many gestational disorders including preterm birth. Currently, there are no…”
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The Stimulation of HSD17B7 Expression by Estradiol Provides a Powerful Feed-Forward Mechanism for Estradiol Biosynthesis in Breast Cancer Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-05-2011)“…Estradiol enhances its own synthesis in breast cancer cells by stimulating transcription of the hsd17b7 gene through ERα activation and NF1 recruitment. Our…”
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Generation of Mice Expressing Only the Long Form of the Prolactin Receptor Reveals That Both Isoforms of the Receptor Are Required for Normal Ovarian Function
Published in Biology of reproduction (01-03-2012)“…Prolactin (PRL), a pleiotropic hormone essential for maintenance of corpus luteum (CL) function and pregnancy, transduces its signal through two types of…”
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Prolactin Receptor-Associated Protein/17β-Hydroxysteroid Dehydrogenase Type 7 Gene (Hsd17b7) Plays a Crucial Role in Embryonic Development and Fetal Survival
Published in Molecular endocrinology (Baltimore, Md.) (01-10-2008)“…Our laboratory has previously cloned and purified a protein named PRAP (prolactin receptor-associated protein) that was shown to be a novel 17β-hydroxysteroid…”
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Prolactin Signaling through the Short Form of Its Receptor Represses Forkhead Transcription Factor FOXO3 and Its Target Gene Galt Causing a Severe Ovarian Defect
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2008)“…Prolactin (PRL) is a hormone with over 300 biological activities. Although the signaling pathway downstream of the long form of its receptor (RL) has been well…”
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Regulation of Transcription Factors and Repression of Sp1 by Prolactin Signaling Through the Short Isoform of Its Cognate Receptor
Published in Endocrinology (Philadelphia) (01-07-2009)“…Prolactin (PRL) affects the development and function of the reproductive system by binding to two types of receptors, which differ by the size of their…”
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Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues
Published in Reproductive biology and endocrinology (24-08-2009)“…It has been well established that prolactin (PRL) signals through the long form of its receptor (PRL-RL) and activates the Jak/Stat pathway for transcription…”
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Inhibition of MAPK by prolactin signaling through the short form of its receptor in the ovary and decidua: involvement of a novel phosphatase
Published in The Journal of biological chemistry (04-03-2011)“…Prolactin (PRL) is essential for normal reproduction and signals through two types of receptors, the short (PRL-RS) and long (PRL-RL) form. We have previously…”
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Prolactin and Dexamethasone Regulate Second Messenger-Stimulated Cl^- Secretion in Mammary Epithelia
Published in Journal of Signal Transduction (01-01-2012)“…Mammary gland ion transport is essential for lactation and is regulated by prolactin and glucocorticoids. This study delineates the roles of prolactin…”
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Involvement of Cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) in Interleukin 11 Stimulation of Decidualization in Mice
Published in Biology of reproduction (2008)“…Interleukin 11 receptor alpha (Il11ra) null mice are infertile due to defective decidualization and abnormal trophoblast invasion. We have previously shown in…”
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Inhibition of MAPK by Prolactin Signaling through the Short Form of Its Receptor in the Ovary and Decidua
Published in The Journal of biological chemistry (04-03-2011)“…Prolactin (PRL) is essential for normal reproduction and signals through two types of receptors, the short (PRL-RS) and long (PRL-RL) form. We have previously…”
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Generation of Mice Expressing Only the Long Form of the Prolactin Receptor Reveals That Both Isoforms of the Receptor Are Required for Normal Ovarian Function1
Published in Biology of reproduction (01-03-2012)“…Prolactin (PRL), a pleiotropic hormone essential for maintenance of corpus luteum (CL) function and pregnancy, transduces its signal through two types of…”
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Involvement of Cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) in Interleukin 11 Stimulation of Decidualization in Mice1
Published in Biology of reproduction (01-01-2008)“…Interleukin 11 receptor alpha (Il11ra) null mice are infertile due to defective decidualization and abnormal trophoblast invasion. We have previously shown in…”
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Prolactin receptor-associated protein/17beta-hydroxysteroid dehydrogenase type 7 gene (Hsd17b7) plays a crucial role in embryonic development and fetal survival
Published in Molecular endocrinology (Baltimore, Md.) (01-10-2008)“…Our laboratory has previously cloned and purified a protein named PRAP (prolactin receptor-associated protein) that was shown to be a novel…”
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The Large Luteal Cells-Derived PRAP/HSD17B7: An Enzyme with a Split Personality.Geula Gibori, Ph.D
Published in Biology of reproduction (01-07-2009)Get full text
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The role of interleukin-11 in pregnancy involves up-regulation of alpha2-macroglobulin gene through janus kinase 2-signal transducer and activator of transcription 3 pathway in the decidua
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2006)“…IL-11 expressed by endometrial stromal cells is crucial for normal pregnancy. IL-11 receptor alpha (IL-11Ralpha) null mice are infertile due to abnormal…”
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