Search Results - "Sanganahalli, Basavaraju G."

Decreased Subcortical Cholinergic Arousal in Focal Seizures by Motelow, Joshua E., Li, Wei, Zhan, Qiong, Mishra, Asht M., Sachdev, Robert N.S., Liu, Geoffrey, Gummadavelli, Abhijeet, Zayyad, Zaina, Lee, Hyun Seung, Chu, Victoria, Andrews, John P., Englot, Dario J., Herman, Peter, Sanganahalli, Basavaraju G., Hyder, Fahmeed, Blumenfeld, Hal

“…Impaired consciousness in temporal lobe seizures has a major negative impact on quality of life. The prevailing view holds that this disorder impairs…”
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Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions by de Arce, Karen Perez, Ribic, Adema, Chowdhury, Dhrubajyoti, Watters, Katherine, Thompson, Garth J., Sanganahalli, Basavaraju G., Lippard, Elizabeth T. C., Rohlmann, Astrid, Strittmatter, Stephen M., Missler, Markus, Hyder, Fahmeed, Biederer, Thomas

“…Multiple trans-synaptic complexes organize synapse development, yet their roles in the mature brain and cooperation remain unclear. We analyzed the…”
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Decreased resting functional connectivity after traumatic brain injury in the rat by Mishra, Asht Mangal, Bai, Xiaoxiao, Sanganahalli, Basavaraju G, Waxman, Stephen G, Shatillo, Olena, Grohn, Olli, Hyder, Fahmeed, Pitkänen, Asla, Blumenfeld, Hal

“…Traumatic brain injury (TBI) contributes to about 10% of acquired epilepsy. Even though the mechanisms of post-traumatic epileptogenesis are poorly known, a…”
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Orthonasal versus retronasal glomerular activity in rat olfactory bulb by fMRI by Sanganahalli, Basavaraju G., Baker, Keeley L., Thompson, Garth J., Herman, Peter, Shepherd, Gordon M., Verhagen, Justus V., Hyder, Fahmeed

“…Odorants can reach olfactory receptor neurons (ORNs) by two routes: orthonasally, when volatiles enter the nasal cavity during inhalation/sniffing, and…”
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APOE genotype-dependent pharmacogenetic responses to rapamycin for preventing Alzheimer's disease by Lin, Ai-Ling, Parikh, Ishita, Yanckello, Lucille M., White, Renee S., Hartz, Anika M.S., Taylor, Chase E., McCulloch, Scott D., Thalman, Scott W., Xia, Mengfan, McCarty, Katie, Ubele, Margo, Head, Elizabeth, Hyder, Fahmeed, Sanganahalli, Basavaraju G.

“…The ε4 allele of Apolipoprotein (APOE4) is the strongest genetic risk factor for Alzheimer's disease (AD), the most common form of dementia. Cognitively normal…”
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Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures by McCafferty, Cian, Gruenbaum, Benjamin F., Tung, Renee, Li, Jing-Jing, Zheng, Xinyuan, Salvino, Peter, Vincent, Peter, Kratochvil, Zachary, Ryu, Jun Hwan, Khalaf, Aya, Swift, Kohl, Akbari, Rashid, Islam, Wasif, Antwi, Prince, Johnson, Emily A., Vitkovskiy, Petr, Sampognaro, James, Freedman, Isaac G., Kundishora, Adam, Depaulis, Antoine, David, François, Crunelli, Vincenzo, Sanganahalli, Basavaraju G., Herman, Peter, Hyder, Fahmeed, Blumenfeld, Hal

“…Absence seizures are brief episodes of impaired consciousness, behavioral arrest, and unresponsiveness, with yet-unknown neuronal mechanisms. Here we report…”
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Thalamic activations in rat brain by fMRI during tactile (forepaw, whisker) and non-tactile (visual, olfactory) sensory stimulations by Sanganahalli, Basavaraju G, Thompson, Garth J, Parent, Maxime, Verhagen, Justus V, Blumenfeld, Hal, Herman, Peter, Hyder, Fahmeed

“…The thalamus is a crucial subcortical hub that impacts cortical activity. Tracing experiments in animals and post-mortem humans suggest rich morphological…”
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Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI by HERMAN, Peter, SANGANAHALLI, Basavaraju G, BLUMENFELD, Hal, ROTHMAN, Douglas L, HYDER, Fahmeed

“…Layer-specific neurophysiologic, hemodynamic, and metabolic measurements are needed to interpret high-resolution functional magnetic resonance imaging (fMRI)…”
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Afatinib plus Cetuximab Delays Resistance Compared to Single-Agent Erlotinib or Afatinib in Mouse Models of TKI-Naïve EGFR L858R-Induced Lung Adenocarcinoma by Pirazzoli, Valentina, Ayeni, Deborah, Meador, Catherine B, Sanganahalli, Basavaraju G, Hyder, Fahmeed, de Stanchina, Elisa, Goldberg, Sarah B, Pao, William, Politi, Katerina

“…The EGFR tyrosine kinase inhibitors (TKIs), erlotinib and afatinib, have transformed the treatment of advanced EGFR-mutant lung adenocarcinoma. However, almost…”
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Where fMRI and electrophysiology agree to disagree: corticothalamic and striatal activity patterns in the WAG/Rij rat by Mishra, Asht Mangal, Ellens, Damien J, Schridde, Ulrich, Motelow, Joshua E, Purcaro, Michael J, DeSalvo, Matthew N, Enev, Miro, Sanganahalli, Basavaraju G, Hyder, Fahmeed, Blumenfeld, Hal

“…The relationship between neuronal activity and hemodynamic changes plays a central role in functional neuroimaging. Under normal conditions and in neurological…”
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Hypofrontality and Posterior Hyperactivity in Early Schizophrenia: Imaging and Behavior in a Preclinical Model by Kaneko, Gen, Sanganahalli, Basavaraju G, Groman, Stephanie M, Wang, Helen, Coman, Daniel, Rao, Jyotsna, Herman, Peter, Jiang, Lihong, Rich, Katherine, de Graaf, Robin A, Taylor, Jane R, Hyder, Fahmeed

“…Abstract Background Schizophrenia is a debilitating neuropsychiatric disorder typically diagnosed from late adolescence to adulthood. Subthreshold behavioral…”
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Energetics of neuronal signaling and fMRI activity by Maandag, Natasja J.G, Coman, Daniel, Sanganahalli, Basavaraju G, Herman, Peter, Smith, Arien J, Blumenfeld, Hal, Shulman, Robert G, Hyder, Fahmeed

“…Energetics of resting and evoked fMRI signals were related to localized ensemble firing rates (ν) measured by electrophysiology in rats. Two different…”
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Mitochondrial functional state impacts spontaneous neocortical activity and resting state FMRI by Sanganahalli, Basavaraju G, Herman, Peter, Hyder, Fahmeed, Kannurpatti, Sridhar S

“…Mitochondrial Ca(2+) uptake, central to neural metabolism and function, is diminished in aging whereas enhanced after acute/sub-acute traumatic brain injury…”
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Functional MRI and neural responses in a rat model of Alzheimer's disease by Sanganahalli, Basavaraju G., Herman, Peter, Behar, Kevin L., Blumenfeld, Hal, Rothman, Douglas L., Hyder, Fahmeed

“…Based on the hypothesis that brain plaques and tangles can affect cortical function in Alzheimer's disease (AD), we investigated functional responses in an AD…”
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Distributions of Irritative Zones Are Related to Individual Alterations of Resting-State Networks in Focal Epilepsy by Song, Yinchen, Sanganahalli, Basavaraju G, Hyder, Fahmeed, Lin, Wei-Chiang, Riera, Jorge J

“…Alterations in the connectivity patterns of the fMRI-based resting-state networks (RSNs) have been reported in several types of epilepsies. Evidence pointed…”
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Lateralized Supraspinal Functional Connectivity Correlate with Pain and Motor Dysfunction in Rat Hemicontusion Cervical Spinal Cord Injury by Sanganahalli, Basavaraju G, Pavuluri, Swathi, Chitturi, Jyothsna, Herman, Peter, Elkabes, Stella, Heary, Robert, Hyder, Fahmeed, Kannurpatti, Sridhar S

“…Afferent nociceptive activity in the reorganizing spinal cord after SCI influences supraspinal regions to establish pain. Clinical evidence of poor motor…”
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Frequency-dependent tactile responses in rat brain measured by functional MRI by Sanganahalli, Basavaraju G., Herman, Peter, Hyder, Fahmeed

“…We measured frequency‐dependent functional MRI (fMRI) activations (at 11.7 T) in the somatosensory cortex with whisker and forepaw stimuli in the same…”
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Multimodal measurements of blood plasma and red blood cell volumes during functional brain activation by Herman, Peter, Sanganahalli, Basavaraju G, Hyder, Fahmeed

“…As an alternative to functional magnetic resonance imaging (fMRI) with blood oxygenation level dependent (BOLD) contrast, cerebral blood volume (CBV)-weighted…”
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Tactile and non-tactile sensory paradigms for fMRI and neurophysiologic studies in rodents by Sanganahalli, Basavaraju G, Bailey, Christopher J, Herman, Peter, Hyder, Fahmeed

“…Functional magnetic resonance imaging (fMRI) has become a popular functional imaging tool for human studies. Future diagnostic use of fMRI depends, however, on…”
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Kaempferol Treatment after Traumatic Brain Injury during Early Development Mitigates Brain Parenchymal Microstructure and Neural Functional Connectivity Deterioration at Adolescence by Parent, Maxime, Chitturi, Jyothsna, Santhakumar, Vijayalakshmi, Hyder, Fahmeed, Sanganahalli, Basavaraju G, Kannurpatti, Sridhar S

“…Targeting mitochondrial ion homeostasis using Kaempferol, a mitochondrial Ca uniporter channel activator, improves energy metabolism and behavior soon after a…”
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