Search Results - "Sang, Qing"
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1
Genetic factors as potential molecular markers of human oocyte and embryo quality
Published in Journal of assisted reproduction and genetics (01-05-2021)“…Successful human reproduction requires gamete maturation, fertilization, and early embryonic development. Human oocyte maturation includes nuclear and…”
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2
Microplastics exposure affects neural development of human pluripotent stem cell-derived cortical spheroids
Published in Journal of hazardous materials (05-08-2022)“…Plastics have been part of our ecosystem for about a century and their degradation by different environmental factors produce secondary microplastics (MPs). To…”
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3
Understanding the genetics of human infertility
Published in Science (American Association for the Advancement of Science) (14-04-2023)“…Reproduction involves a wide range of biological processes, including organ formation and development, neuroendocrine regulation, hormone production, and…”
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4
Functionalization of Brain Region-specific Spheroids with Isogenic Microglia-like Cells
Published in Scientific reports (30-07-2019)“…Current brain spheroids or organoids derived from human induced pluripotent stem cells (hiPSCs) still lack a microglia component, the resident immune cells in…”
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5
Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
Published in Nature reviews. Drug discovery (01-06-2007)“…Matrix metalloproteinases (MMPs) have outgrown the field of extracellular-matrix biology and have progressed towards being important regulatory molecules in…”
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6
Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes
Published in Chemical research in toxicology (19-04-2021)“…Microplastics in the environment produced by decomposition of globally increasing waste plastics have become a dominant component of both water and air…”
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Evaluating the Catalytic Efficiency of the Human Membrane-type 1 Matrix Metalloproteinase (MMP-14) Using AuNP–Peptide Conjugates
Published in Journal of the American Chemical Society (01-03-2023)“…Interactions of plasmonic nanocolloids such as gold nanoparticles and nanorods with proximal dye emitters result in efficient quenching of the dye…”
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8
Effects of Polystyrene Microplastics on Human Kidney and Liver Cell Morphology, Cellular Proliferation, and Metabolism
Published in ACS omega (27-09-2022)“…Microplastics have gained much attention due to their prevalence and abundance in our everyday lives. They have been detected in household items such as sugar,…”
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9
MOS is a novel genetic marker for human early embryonic arrest and fragmentation
Published in EMBO molecular medicine (07-12-2021)“…Early embryonic arrest and fragmentation (EEAF) is a common phenotype observed in in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI)…”
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10
Immune landscape of human prostate cancer: immune evasion mechanisms and biomarkers for personalized immunotherapy
Published in BMC cancer (18-06-2020)“…Despite recent advances in cancer immunotherapy, the efficacy of these therapies for the treatment of human prostate cancer patients is low due to the complex…”
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11
Expanding the genetic and phenotypic spectrum of female infertility caused by TLE6 mutations
Published in Journal of assisted reproduction and genetics (01-02-2020)“…Purpose The present study was intended to identify genetic causes of infertile patients with recurrent failure of in vitro fertilization (IVF)/intracytoplasmic…”
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12
The Role of Interleukin‐1 in Inflammatory and Malignant Human Skin Diseases and the Rationale for Targeting Interleukin‐1 Alpha
Published in Medicinal research reviews (01-01-2017)“…Inflammation plays a major role in the induction and progression of several skin diseases. Overexpression of the major epidermal proinflammatory cytokines…”
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13
Quantum Dot–Peptide Conjugates as Energy Transfer Probes for Sensing the Proteolytic Activity of Matrix Metalloproteinase-14
Published in Analytical chemistry (Washington) (07-02-2023)“…We detail the assembly and characterization of quantum dot (QD)−dye conjugates constructed using a peptide bridge specifically designed to recognize and…”
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14
Physiological and pathological mechanisms of oocyte meiosis
Published in Yíchuán (20-12-2023)“…Normal oogenesis is crucial to successful reproduction. During the human female fetal stage, primordial germ cells transform from mitosis to meiosis. After…”
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15
Exploring background mutational processes to decipher cancer genetic heterogeneity
Published in Nucleic acids research (03-07-2017)“…Much remains unknown about the progression and heterogeneity of mutational processes in different cancers and their diagnostic and clinical potential. A…”
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16
Identification of MicroRNAs in Human Follicular Fluid: Characterization of MicroRNAs That Govern Steroidogenesis in Vitro and Are Associated With Polycystic Ovary Syndrome in Vivo
Published in The journal of clinical endocrinology and metabolism (01-07-2013)“…Context: Human follicular fluid is a combination of proteins, metabolites, and ionic compounds that is indicative of the general state of follicular metabolism…”
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17
Novel mutations in PATL2: expanding the mutational spectrum and corresponding phenotypic variability associated with female infertility
Published in Journal of human genetics (01-05-2019)“…Oocyte maturation arrest results in primary female infertility, but the genetic etiology of this phenotype remains largely unknown. Previously, we and other…”
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18
MicroRNA156 conditions auxin sensitivity to enable growth plasticity in response to environmental changes in Arabidopsis
Published in Nature communications (22-03-2023)“…MicroRNAs (miRNAs) play diverse roles in plant development, but whether and how miRNAs participate in thermomorphogenesis remain ambiguous. Here we show that…”
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Cytochrome P450-2D6: A novel biomarker in liver cancer health disparity
Published in PloS one (01-10-2021)“…Liver cancer morbidity and mortality rates differ among ethnic groups. In the United States, the burden of liver cancer in Asian Americans (AS) is higher…”
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Secretome analysis reveals upregulated granzyme B in human androgen-repressed prostate cancer cells with mesenchymal and invasive phenotype
Published in PloS one (07-08-2020)“…Epithelial-mesenchymal transition (EMT) is a critical early step in cancer metastasis and a complex process that involves multiple factors. In this study, we…”
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