Search Results - "Sang, Q X"

Global alteration in gene expression profiles of deciduas from women with idiopathic recurrent pregnancy loss by KRIEG, S. A, FAN, X, HONG, Y, SANG, Q.-X, GIACCIA, A, WESTPHAL, L. M, LATHI, R. B, KRIEG, A. J, NAYAK, N. R

“…Recurrent pregnancy loss (RPL) occurs in ∼5% of women. However, the etiology is still poorly understood. Defects in decidualization of the endometrium during…”
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Matrix metalloproteinase inhibition in atherosclerosis and stroke by Roycik, M D, Myers, J S, Newcomer, R G, Sang, Q-X A

“…Matrix metalloproteinases (MMPs) are a family of tightly regulated, zinc-dependent proteases that degrade extracellular matrix (ECM), cell surface, and…”
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A fresh prospect of extracellular matrix hydrolytic enzymes and their substrates by Roycik, M D, Fang, X, Sang, Q-X

“…Extracellular matrix (ECM) and ECM-hydrolytic enzymes play critical roles in reproduction, development, morphogenesis, wound healing, tissue repair,…”
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Matrix metalloproteinase-9/gelatinase B is a putative therapeutic target of chronic obstructive pulmonary disease and multiple sclerosis by Muroski, M E, Roycik, M D, Newcomer, R G, Van den Steen, P E, Opdenakker, G, Monroe, H R, Sahab, Z J, Sang, Q-X

“…Matrix metalloproteinases (MMPs) are a large family of proteolytic enzymes involved in an array of physiological and pathological processes from development,…”
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Soluble laminin and arginine-glycine-aspartic acid containing peptides differentially regulate type IV collagenase messenger RNA, activation, and localization in testicular cell culture by Q X Sang, E W Thompson, D Grant, W G Stetler-Stevenson, S W Byers

“…Rat testicular cells in culture produce several metalloproteinases including type IV collagenases (Sang et al. Biol Reprod 1990; 43:946-955, 956-964). We have…”
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Secreted metalloproteinases in testicular cell culture by Sang, Q X, Dym, M, Byers, S W

“…It is well known that cultured Sertoli cells secrete plasminogen activators (Lacroix et al., Mol Cell Endocrinol 1977; 9:227-236; Hettle et al., Biol Reprod…”
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Identification of type IV collagenase in rat testicular cell culture: influence of peritubular-Sertoli cell interactions by Q X Sang, W G Stetler-Stevenson, L A Liotta, S W Byers

“…In the testis, interactions between peritubular cells (mesenchyme) and Sertoli cells (epithelium), together with proteolytic remodeling of the extracellular…”
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Complex role of matrix metalloproteinases in angiogenesis by Sang, Q X

“…Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) play a significant role in regulating angiogenesis, the process of new…”
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Abstract P1-01-18: Disrupting interactions between human breast cancer cells, adipocytes, and macrophages by Vallega, KA, Sang, Q-XA

“…Abstract An increasing number of studies have found that other cells in the tumor microenvironment can influence tumor cells. Adipocytes, which were once…”
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Abstract P3-05-18: The complex landscape of breast cancer immune evasion and its implications to personalized and combined immunotherapy by Bou-Dargham, MJ, Liu, Y, Sang, Q-XA, Zhang, J

“…Abstract Cancer immunotherapy activates the patient's immune system to recognize and kill cancer cells. The efficacy of immunotherapy in human breast cancer…”
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Identification and Characterization of Human Endometase (Matrix Metalloproteinase-26) from Endometrial Tumor by Park, Hyun I., Ni, Jian, Gerkema, Ferry E., Liu, Ding, Belozerov, Vladimir E., Sang, Qing-Xiang Amy

“…We report the discovery, cloning, and characterization of a novel human matrix metalloproteinase 26 (MMP-26) (matrixin) gene, endometase, an endometrial…”
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A Novel Protease-docking Function of Integrin at Invadopodia by Mueller, Susette C., Ghersi, Giulio, Akiyama, Steven K., Sang, Qing-Xiang Amy, Howard, Linda, Pineiro-Sanchez, Mayra, Nakahara, Hirokazu, Yeh, Yunyun, Chen, Wen-Tien

“…Invadopodia are membrane extensions of aggressive tumor cells that function in the activation of membrane-bound proteases occurring during tumor cell invasion…”
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Abhd2, a Candidate Gene Regulating Airway Remodeling in COPD via TGF-β by Lv, Mei-Yu, Jin, Ling-Ling, Sang, Xi-Qiao, Shi, Wen-Chao, Qiang, Li-Xia, Lin, Qing-Yan, Jin, Shou-De

“…The typical characteristic of COPD is airway remodeling, affected by environmental and genetic factors. However, genetic studies on COPD have been limited…”
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Differential Effects of Heparin and Hyaluronic Acid on Neural Patterning of Human Induced Pluripotent Stem Cells by Bejoy, Julie, Wang, Zhe, Bijonowski, Brent, Yang, Mo, Ma, Teng, Sang, Qing-Xiang, Li, Yan

“…A lack of well-established animal models that can efficiently represent human brain pathology has led to the development of human induced pluripotent stem cell…”
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Stimulation of mammary tumorigenesis by systemic tissue inhibitor of Matrix metalloproteinase 4 gene delivery by YANGFU JIANG, MINGSHENG WANG, CELIKER, Mahmut Y, LIU, Yiliang E, SANG, Qing Xiang, GOLDBERG, Itzhak D, SHI, Y. Eric

“…Tissue inhibitors of matrix metalloproteinase (TIMPs) are multifunctional proteins with both matrix metalloproteinase (MMP) inhibitory effects and…”
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Metalloproteinase Disintegrins ADAM8 and ADAM19 Are Highly Regulated in Human Primary Brain Tumors and their Expression Levels and Activities Are Associated with Invasiveness by Wildeboer, Dirk, Naus, Silvia, Sang, Qing-Xiang Amy, Bartsch, Jörg W, Pagenstecher, Axel

“…Patients with primary brain tumors have bleak prognoses and there is an urgent desire to identify new markers for sensitive diagnosis and new therapeutic…”
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Structure-function analysis of the ADAM family of disintegrin-like and metalloproteinase-containing proteins (review) by Stone, A L, Kroeger, M, Sang, Q X

“…The ADAMs belong to a disintegrin-like and metalloproteinase-containing protein family that are zinc-dependent metalloproteinases. These proteins share all or…”
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The significance of focal myoepithelial cell layer disruptions in human breast tumor invasion: a paradigm shift from the “protease-centered” hypothesis by Man, Yan-Gao, Sang, Qing-Xiang Amy

“…Human breast epithelium and the stroma are separated by a layer of myoepithelial (ME) cells and basement membrane, whose disruption is a prerequisite for tumor…”
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Expression and Enzymatic Activity of Human Disintegrin and Metalloproteinase ADAM19/Meltrin Beta by Wei, Ping, Zhao, Yun-Ge, Zhuang, Li, Ruben, Steve, Sang, Qing-Xiang Amy

“…The adamalysins are involved in proteolysis, adhesion, fusion, and intracellular signaling. Human ADAM19/adamalysin-19 (A disintegrin and metalloproteinase 19)…”
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Proteases in seminiferous epithelium remodeling by Sang, Q X, Dym, M, Byers, S W

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