Search Results - "Sanford, R."

Asoprisnil, a Selective Progesterone Receptor Modulator (SPRM), Inhibits Melanosome Export in B16F10 Cells and HEMn-DP Melanocytes by Goenka, Shilpi, R Simon, Sanford

“…Previous studies have reported that estrogen hormone promotes melanogenesis while progesterone inhibits it. A selective estrogen receptor modulator (SERM),…”
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Vertical Scales, Deceleration, and Empirical Benchmarks for Growth by Student, Sanford R.

“…Empirical growth benchmarks, as introduced by Hill, Bloom, Black, and Lipsey (2008), are a well-known way to contextualize effect sizes in education research…”
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Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers by Redondo-Morata, Lorena, Lea Sanford, R., Andersen, Olaf S., Scheuring, Simon

“…Many drugs and other xenobiotics may reach systemic concentrations where they interact not only with the proteins that are their therapeutic targets but also…”
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Novel Chemically Modified Curcumin (CMC) Analogs Exhibit Anti-Melanogenic Activity in Primary Human Melanocytes by Goenka, Shilpi, Simon, Sanford R.

“…Hyperpigmentation is a dermatological condition characterized by the overaccumulation and/or oversecretion of melanin pigment. The efficacy of curcumin as an…”
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Activation of Insulin Signaling by Botanical Products by Rosenzweig, Tovit, Sampson, Sanford R

“…Type 2 diabetes (T2D) is a worldwide health problem, ranked as one of the leading causes for severe morbidity and premature mortality in modern society…”
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Comparative study of doxycycline, sancycline, and 4-dedimethylamino sancycline (CMT-3) on epidermal melanogenesis by Goenka, Shilpi, Simon, Sanford R.

“…Melanogenesis is regulated by melanocytes, which synthesize the pigment melanin inside melanosomes; these melanosomes are exported through dendritic extensions…”
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Insects and associated arthropods analyzed during medicolegal death investigations in Harris County, Texas, USA: January 2013- April 2016 by Sanford, Michelle R

“…The application of insect and arthropod information to medicolegal death investigations is one of the more exacting applications of entomology. Historically…”
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The RNAissance family: SR proteins as multifaceted regulators of gene expression by Howard, Jonathan M., Sanford, Jeremy R.

“…Serine and arginine‐rich (SR) proteins play multiple roles in the eukaryotic gene expression pathway. Initially described as constitutive and alternative…”
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Effects of E-Cigarette Refill Liquid Flavorings with and without Nicotine on Human Retinal Pigment Epithelial Cells: A Preliminary Study by Goenka, Shilpi, Simon, Sanford R

“…Smoking is an etiologic factor for age-related macular degeneration (AMD). Although cigarette smoke has been extensively researched for retinal pigment…”
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Organogold drug Auranofin exhibits anti-melanogenic activity in B16F10 and MNT-1 melanoma cells by Goenka, Shilpi, Simon, Sanford R.

“…Auranofin (AF) is an organogold FDA-approved drug for treating rheumatism and has been repurposed for several pharmacological applications based on its…”
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Anti-melanogenic activity of ellagitannin casuarictin in B16F10 mouse melanoma cells by Goenka, Shilpi, Ceccoli, Joseph, Simon, Sanford R.

“…Ellagitannins such as casuarictin (CAS), isolated from clove extracts, have been shown to have superior benefits such as antioxidant and anti-inflammatory…”
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A Novel Pro-Melanogenic Effect of Standardized Dry Olive Leaf Extract on Primary Human Melanocytes from Lightly Pigmented and Moderately Pigmented Skin by Goenka, Shilpi, Simon, Sanford R

“…Benolea (EFLA 943) is a standardized dry olive leaf extract (DOLE) considered safe for food consumption and has demonstrated superior pharmaceutical benefits…”
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Novel Isoprene Sensor for a Flu Virus Breath Monitor by Gouma, Pelagia-Irene, Wang, Lisheng, Simon, Sanford R, Stanacevic, Milutin

“…A common feature of the inflammatory response in patients who have actually contracted influenza is the generation of a number of volatile products of the…”
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Supporting the Interpretive Validity of Student‐Level Claims in Science Assessment with Tiered Claim Structures by Student, Sanford R., Gong, Brian

“…We address two persistent challenges in large‐scale assessments of the Next Generation Science Standards: (a) the validity of score interpretations that target…”
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Depigmenting effect of Xanthohumol from hop extract in MNT-1 human melanoma cells and normal human melanocytes by Goenka, Shilpi, Simon, Sanford R.

“…Xanthohumol (XH) is the most abundant prenylated flavonoid found in the hop plant (Humulus lupulus L.) and has previously been shown to have depigmenting…”
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The Splicing Factor SF2/ASF Regulates Translation Initiation by Enhancing Phosphorylation of 4E-BP1 by Michlewski, Gracjan, Sanford, Jeremy R., Cáceres, Javier F.

“…The SR protein SF2/ASF has been initially characterized as a splicing factor but has also been shown to mediate postsplicing activities such as mRNA export and…”
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RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation by Palanichamy, Jayanth Kumar, Tran, Tiffany M, Howard, Jonathan M, Contreras, Jorge R, Fernando, Thilini R, Sterne-Weiler, Timothy, Katzman, Sol, Toloue, Masoud, Yan, Weihong, Basso, Giuseppe, Pigazzi, Martina, Sanford, Jeremy R, Rao, Dinesh S

“…Posttranscriptional control of gene expression is important for defining both normal and pathological cellular phenotypes. In vitro, RNA-binding proteins…”
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Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles by Doktorova, Milka, Heberle, Frederick A., Marquardt, Drew, Rusinova, Radda, Sanford, R. Lea, Peyear, Thasin A., Katsaras, John, Feigenson, Gerald W., Weinstein, Harel, Andersen, Olaf S.

“…Unlike most transmembrane proteins, phospholipids can migrate from one leaflet of the membrane to the other. Because this spontaneous lipid translocation…”
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Loss of exon identity is a common mechanism of human inherited disease by Sterne-Weiler, Timothy, Howard, Jonathan, Mort, Matthew, Cooper, David N, Sanford, Jeremy R

“…It is widely accepted that at least 10% of all mutations causing human inherited disease disrupt splice-site consensus sequences. In contrast to splice-site…”
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Inhibitory Effects of the Bioactive Thermorubin Isolated from the Fungus Thermoactinomyces Antibioticus on Melanogenesis by Goenka, Shilpi, R. Simon, Sanford

“…Skin hyperpigmentation disorders arise due to aberrant regulation of melanin synthesis and export. Current treatments include natural compounds like kojic acid…”
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