Search Results - "Sanford, James A"

Functions of the skin microbiota in health and disease by Sanford, James A, Gallo, Richard L

“…Highlights • The skin has many different distinct surface environments. • Microbial communities inhabiting the skin are diverse and complex. • Skin microbial…”
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Short-Chain Fatty Acids from Cutibacterium acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes by Sanford, James A, O'Neill, Alan M, Zouboulis, Christos C, Gallo, Richard L

“…The regulation of cutaneous inflammatory processes is essential for the human skin to maintain homeostasis in the presence of the dense communities of resident…”
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Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis by Williams, Michael R, Costa, Stephen K, Zaramela, Livia S, Khalil, Shadi, Todd, Daniel A, Winter, Heather L, Sanford, James A, O'Neill, Alan M, Liggins, Marc C, Nakatsuji, Teruaki, Cech, Nadja B, Cheung, Ambrose L, Zengler, Karsten, Horswill, Alexander R, Gallo, Richard L

“…Colonization of the skin by is associated with exacerbation of atopic dermatitis (AD), but any direct mechanism through which dysbiosis of the skin microbiome…”
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Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury by Zhang, Ling-juan, Sen, George L., Ward, Nicole L., Johnston, Andrew, Chun, Kimberly, Chen, Yifang, Adase, Christopher, Sanford, James A., Gao, Nina, Chensee, Melanie, Sato, Emi, Fritz, Yi, Baliwag, Jaymie, Williams, Michael R., Hata, Tissa, Gallo, Richard L.

“…Type 1 interferons (IFNs) promote inflammation in the skin but the mechanisms responsible for inducing these cytokines are not well understood. We found that…”
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Innate Immune Dysfunction in Rosacea Promotes Photosensitivity and Vascular Adhesion Molecule Expression by Kulkarni, Nikhil N., Takahashi, Toshiya, Sanford, James A., Tong, Yun, Gombart, Adrian F., Hinds, Brian, Cheng, Joyce Y., Gallo, Richard L.

“…Rosacea is a chronic skin disease characterized by photosensitivity, abnormal dermal vascular behavior, inflammation, and enhanced expression of the…”
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Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome by Williams, Michael R., Cau, Laura, Wang, Yichen, Kaul, Drishti, Sanford, James A., Zaramela, Livia S., Khalil, Shadi, Butcher, Anna M., Zengler, Karsten, Horswill, Alexander R., Dupont, Christopher L., Hovnanian, Alain, Gallo, Richard L.

“…Netherton syndrome (NS) is a monogenic skin disease resulting from loss of function of lymphoepithelial Kazal-type-related protease inhibitor (LEKTI-1). In…”
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Insights from a workplace SARS-CoV-2 specimen collection program, with genomes placed into global sequence phylogeny by Leiser, Owen P, Auberry, Deanna L, Bakker, Erica, Chrisler, Will, Engbrecht, Kristin, Engelmann, Heather, Fansler, Sarah, Gerbasi, Vincent, Hansen, Joshua, Hutchinson, Chelsea, Hutchison, Janine, Lancaster, Mary J, Lawrence, Kathleen, Melville, Angela, Mobberley, Jennifer, O'Bryon, Isabelle, Oxford, Kristie L, Oxford, Tessa, Phillips, Shelby, Rodda, Kabrena E, Sanford, James A, Schepmoes, Athena, Staley, Brian E, Terrell, Kelcey, Victry, Kristin, Warner, Cynthia, Omberg, Kristin M

“…In 2020, the Department of Energy established the National Virtual Biotechnology Laboratory (NVBL) to address key challenges associated with COVID-19. As part…”
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A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection by Deatherage Kaiser, Brooke L, Li, Jie, Sanford, James A, Kim, Young-Mo, Kronewitter, Scott R, Jones, Marcus B, Peterson, Christine T, Peterson, Scott N, Frank, Bryan C, Purvine, Samuel O, Brown, Joseph N, Metz, Thomas O, Smith, Richard D, Heffron, Fred, Adkins, Joshua N

“…The potential for commensal microorganisms indigenous to a host (the 'microbiome' or 'microbiota') to alter infection outcome by influencing host-pathogen…”
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IL-17A Has Some Nerve by Sanford, James A., Gallo, Richard L.

“…Sensory neurons are important in controlling cutaneous inflammation, but the role of neurons in host antimicrobial defense was relatively unknown. Kaplan and…”
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The Parathyroid Hormone Second Receptor PTH2R and its Ligand Tuberoinfundibular Peptide of 39 Residues TIP39 Regulate Intracellular Calcium and Influence Keratinocyte Differentiation by Sato, Emi, Muto, Jun, Zhang, Ling-Juan, Adase, Christopher A., Sanford, James A., Takahashi, Toshiya, Nakatsuji, Teruaki, Usdin, Ted B., Gallo, Richard L.

“…Genes related to the parathyroid hormone (PTH) influence cutaneous immune defense and development, but the full functions of the PTH family in cutaneous…”
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Assessment of TMT Labeling Efficiency in Large-Scale Quantitative Proteomics: The Critical Effect of Sample pH by Hutchinson-Bunch, Chelsea, Sanford, James A, Hansen, Joshua R, Gritsenko, Marina A, Rodland, Karin D, Piehowski, Paul D, Qian, Wei-Jun, Adkins, Joshua N

“…Isobaric labeling via tandem mass tag (TMT) reagents enables sample multiplexing prior to LC–MS/MS, facilitating high-throughput large-scale quantitative…”
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Hyaluronidase inhibits reactive adipogenesis and inflammation of colon and skin by Dokoshi, Tatsuya, Zhang, Ling-Juan, Nakatsuji, Teruaki, Adase, Christopher A, Sanford, James A, Paladini, Rudolph D, Tanaka, Hiroki, Fujiya, Mikihiro, Gallo, Richard L

“…In this study we evaluated the role of hyaluronan (HA) in reactive adipogenesis, a local expansion of preadipocytes that provides host defense by release of…”
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Comparative omics-driven genome annotation refinement: application across Yersiniae by Schrimpe-Rutledge, Alexandra C, Jones, Marcus B, Chauhan, Sadhana, Purvine, Samuel O, Sanford, James A, Monroe, Matthew E, Brewer, Heather M, Payne, Samuel H, Ansong, Charles, Frank, Bryan C, Smith, Richard D, Peterson, Scott N, Motin, Vladimir L, Adkins, Joshua N

“…Genome sequencing continues to be a rapidly evolving technology, yet most downstream aspects of genome annotation pipelines remain relatively stable or are…”
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Staphylococcus aureus Induces Increased Serine Protease Activity in Keratinocytes by Williams, Michael R., Nakatsuji, Teruaki, Sanford, James A., Vrbanac, Alison F., Gallo, Richard L.

“…Bacteria that reside on the skin can influence the behavior of the cutaneous immune system, but the mechanisms responsible for these effects are incompletely…”
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Novel Functional Residues in the Core Domain of Histone H2B Regulate Yeast Gene Expression and Silencing and Affect the Response to DNA Damage by Kyriss, McKenna N. M., Jin, Yi, Gallegos, Isaura J., Sanford, James A., Wyrick, John J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Insights into posttranslational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP by Meyer, Gretchen A, Ferey, Jeremie L A, Sanford, James A, Fitzgerald, Liam S, Greenberg, Akiva E, Svensson, Kristoffer, Greenberg, Michael J, Schenk, Simon

“…Mice with skeletal muscle-specific and inducible double knockout of the lysine acetyltransferases, p300 (E1A binding protein p300) and CBP (cAMP-response…”
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Non-coding Double-stranded RNA and Antimicrobial Peptide LL-37 Induce Growth Factor Expression from Keratinocytes and Endothelial Cells by Adase, Christopher A., Borkowski, Andrew W., Zhang, Ling-juan, Williams, Michael R., Sato, Emi, Sanford, James A., Gallo, Richard L.

“…A critical function for skin is that when damaged it must simultaneously identify the nature of the injury, repair barrier function, and limit the intrusion of…”
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Evaluation of Differential Peptide Loading on Tandem Mass Tag-Based Proteomic and Phosphoproteomic Data Quality by Sanford, James A, Wang, Yang, Hansen, Joshua R, Gritsenko, Marina A, Weitz, Karl K, Sagendorf, Tyler J, Tognon, Cristina E, Petyuk, Vladislav A, Qian, Wei-Jun, Liu, Tao, Druker, Brian J, Rodland, Karin D, Piehowski, Paul D

“…Global and phosphoproteome profiling has demonstrated great utility for the analysis of clinical specimens. One barrier to the broad clinical application of…”
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IL-1 Receptor–Knockout Mice Develop Epidermal Cysts and Show an Altered Innate Immune Response after Exposure to UVB Radiation by Kulkarni, Nikhil N., Adase, Christopher A., Zhang, Ling-juan, Borkowski, Andrew W., Li, Fengwu, Sanford, James A., Coleman, Daniel J., Aguilera, Carlos, Indra, Arup K., Gallo, Richard L.

“…In this study, we observed that mice lacking the IL-1 receptor (IL-1R) (IL1r–/–) or deficient in IL1-β developed multiple epidermal cysts after chronic UVB…”
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The type2 sarco/endoplasmic reticulum Ca2+ -ATPase is required for TIP39 induced-long term differentiation of keratinocyte by Sato, Emi, Williams, Michael R, Sanford, James A, Nakama, Takekuni, Imafuku, Shinichi, Gallo, Richard L

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