Search Results - "Sanfilippo, Piero"
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Transcriptional Programs of Circuit Assembly in the Drosophila Visual System
Published in Neuron (Cambridge, Mass.) (23-12-2020)“…Precise patterns of synaptic connections between neurons are encoded in their genetic programs. Here, we use single-cell RNA sequencing to profile neuronal…”
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2
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Published in Genome Biology (30-11-2017)“…Drosophila melanogaster has one of best-described transcriptomes of any multicellular organism. Nevertheless, the paucity of 3'-sequencing data in this species…”
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Genome-wide analysis of drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation
Published in Cell reports (Cambridge) (11-12-2014)“…Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion…”
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4
Alternative polyadenylation in the nervous system: To what lengths will 3′ UTR extensions take us?
Published in BioEssays (01-08-2014)“…Alternative cleavage and polyadenylation (APA) can diversify coding and non‐coding regions, but has particular impact on increasing 3′ UTR diversity. Through…”
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5
Synaptic gradients transform object location to action
Published in Nature (London) (19-01-2023)“…To survive, animals must convert sensory information into appropriate behaviours 1 , 2 . Vision is a common sense for locating ethologically relevant stimuli…”
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6
Correction: Neural specificity of the RNA-binding protein Elav is achieved by post-transcriptional repression in non-neural tissues
Published in Development (Cambridge) (15-04-2017)Get full text
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7
Oxygen limitation modulates pH regulation of catabolism and hydrogenases, multidrug transporters, and envelope composition in Escherichia coli K-12
Published in BMC microbiology (06-10-2006)“…In Escherichia coli, pH regulates genes for amino-acid and sugar catabolism, electron transport, oxidative stress, periplasmic and envelope proteins. Many…”
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Genome-wide profiling of the 3' ends of polyadenylated RNAs
Published in Methods (San Diego, Calif.) (15-08-2017)“…•3′-seq is a method to map the 3′ ends of transcripts genome-wide at single nucleotide resolution.•3′-seq provides quantitative measure of 3′ UTR isoforms…”
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Overlapping Activities of ELAV/Hu Family RNA Binding Proteins Specify the Extended Neuronal 3′ UTR Landscape in Drosophila
Published in Molecular cell (01-10-2020)“…The tissue-specific deployment of highly extended neural 3’ UTR isoforms, generated by alternative polyadenylation (APA), is a broad and conserved feature of…”
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10
IsoSCM: improved and alternative 3' UTR annotation using multiple change-point inference
Published in RNA (Cambridge) (01-01-2015)“…Major applications of RNA-seq data include studies of how the transcriptome is modulated at the levels of gene expression and RNA processing, and how these…”
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11
Neural specificity of the RNA-binding protein Elav is achieved by post-transcriptional repression in non-neural tissues
Published in Development (Cambridge) (01-12-2016)“…Drosophila Elav is the founding member of the conserved family of Hu RNA-binding proteins (RBPs), which play crucial and diverse roles in post-transcriptional…”
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12
Constitutive and Conditional Epitope Tagging of Endogenous G-Protein-Coupled Receptors in Drosophila
Published in The Journal of neuroscience (14-08-2024)“…To visualize the cellular and subcellular localization of neuromodulatory G-protein-coupled receptors in , we implement a molecular strategy recently used to…”
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13
Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
Published in Neuron (Cambridge, Mass.) (20-03-2024)“…Neurons express various combinations of neurotransmitter receptor (NR) subunits and receive inputs from multiple neuron types expressing different…”
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14
Publisher Correction: Synaptic gradients transform object location to action
Published in Nature (London) (30-03-2023)Get full text
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15
Characterization of a TUTase/RNase complex required for Drosophila gametogenesis
Published in RNA (Cambridge) (01-03-2017)“…Post-transcriptional regulatory strategies that involve coupling between terminal uridyltransferase (TUTase) and exoribonuclease enzymes have recently been…”
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Homeotic Function of Drosophila Bithorax-Complex miRNAs Mediates Fertility by Restricting Multiple Hox Genes and TALE Cofactors in the CNS
Published in Developmental cell (23-06-2014)“…The Drosophila Bithorax complex (BX-C) Hox cluster contains a bidirectionally transcribed miRNA locus, and a deletion mutant (Δmir) lays no eggs and is…”
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Homeotic function of Drosophila Bithorax-Complex miRNAs mediates fertility by restricting multiple Hox genes and TALE cofactors in the central nervous system
Published in Developmental cell (05-06-2014)“…The Drosophila Bithorax-Complex (BX-C) Hox cluster contains a bidirectionally-transcribed miRNA locus, and a deletion mutant (∆ mir ) lays no eggs and is…”
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18
Genomewide analysis of Drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation
Published in Cell reports (Cambridge) (26-11-2014)“…Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion…”
Get full text
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