Search Results - "Sanfilippo, Cristina"
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CSF N-glycoproteomics for early diagnosis in Alzheimer's disease
Published in Journal of proteomics (10-01-2016)“…This work aims at exploring the human CSF (Cerebrospinal fluid) N-glycome by MALDI MS techniques, in order to assess specific glycosylation pattern(s) in…”
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Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances
Published in Current neuropharmacology (01-01-2023)“…Background: Cholinergic hypofunction and sleep disturbance are hallmarks of Alzheimer’s disease (AD), a progressive disorder leading to neuronal deterioration…”
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Expression of the OAS Gene Family Is Highly Modulated in Subjects Affected by Juvenile Dermatomyositis, Resembling an Immune Response to a dsRNA Virus Infection
Published in International journal of molecular sciences (17-09-2018)“…Juvenile dermatomyositis (JDM) is a systemic, autoimmune, interferon (IFN)-mediated inflammatory muscle disorder that affects children younger than 18 years of…”
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Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients
Published in Cells (Basel, Switzerland) (13-04-2021)“…Alzheimer's disease is a progressive, devastating, and irreversible brain disorder that, day by day, destroys memory skills and social behavior. Despite this,…”
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5
Network perturbation analysis in human bronchial epithelial cells following SARS-CoV2 infection
Published in Experimental cell research (15-10-2020)“…SARS-CoV2, the agent responsible for the current pandemic, is also causing respiratory distress syndrome (RDS), hyperinflammation and high mortality. It is…”
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Increased neurogranin concentrations in cerebrospinal fluid of Alzheimer’s disease and in mild cognitive impairment due to AD
Published in Journal of Neural Transmission (01-12-2016)“…Synaptic dysfunction is linked to both major depressive disorder (MDD) and Alzheimer’s disease (AD). Synapse protein concentrations in cerebrospinal fluid…”
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Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels
Published in Brain research (15-12-2020)“…•Alzheimer's disease positively and negatively regulates the expression levels of CXCR4 and CXCL12 respectively.•AD females exhibit higher expression levels of…”
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Middle-aged healthy women and Alzheimer's disease patients present an overlapping of brain cell transcriptional profile
Published in Neuroscience (15-05-2019)“…Exploring sexual dimorphisms in the brain morphology is important for their impact and therapeutic implications for several neurological diseases. The…”
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CHI3L2 Expression Levels Are Correlated with AIF1, PECAM1, and CALB1 in the Brains of Alzheimer’s Disease Patients
Published in Journal of molecular neuroscience (01-10-2020)“…Alzheimer’s disease (AD) represents one of the main forms of dementia that afflicts our society. The expression of several genes has been associated with…”
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Neuro-immune deconvolution analysis of OAS3 as a transcriptomic central node in HIV-associated neurocognitive disorders
Published in Journal of the neurological sciences (15-03-2023)“…Neurological complications of AIDS (NeuroAIDS) include primary HIV-associated neurocognitive disorder (HAND). OAS3 is an enzyme belonging to the 2′, 5′…”
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Sex difference in CHI3L1 expression levels in human brain aging and in Alzheimer’s disease
Published in Brain research (01-10-2019)“…•Several neurodegenerative diseases show sex differences in prevalence and/or outcome.•Among the cells involved in neurodegenerative diseases, we have the…”
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Sex-dependent neuro-deconvolution analysis of Alzheimer's disease brain transcriptomes according to CHI3L1 expression levels
Published in Journal of neuroimmunology (15-12-2022)“…Glial activation and related neuroinflammatory processes play a key role in the aging and progression of Alzheimer's disease (AD). CHI3L1/ YKL40 is a widely…”
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Skeletal muscle of young females under resistance exercise exhibits a unique innate immune cell infiltration profile compared to males and elderly individuals
Published in Journal of muscle research and cell motility (01-12-2024)“…Muscle damage resulting from physical activities such as exercise triggers an immune response crucial for tissue repair and recovery. This study investigates…”
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Hippocampal transcriptome deconvolution reveals differences in cell architecture of not demented elderly subjects underwent late-life physical activity
Published in Journal of chemical neuroanatomy (01-04-2021)“…•Physical exercise is a powerful variable that can improve cognitive function and delay age-associated cognitive decline.•Deconvolution method represents a new…”
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GNG13 Is a Potential Marker of the State of Health of Alzheimer’s Disease Patients’ Cerebellum
Published in Journal of molecular neuroscience (01-05-2021)“…Brain regions such as the cerebellum (CB) have been neglected for a long time in the study of Alzheimer’s disease (AD) pathogenesis. In reference to a new…”
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Chitinase domain containing 1 increase is associated with low survival rate and M0 macrophages infiltrates in colorectal cancer patients
Published in Pathology, research and practice (01-09-2022)“…Colorectal cancer (CRC) is one of the most common cancers in the world. Here, we undertook an analysis of microarray datasets consisting of colon biopsies of…”
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Executive Dysfunctions in Migraine With and Without Aura: What Is the Role of White Matter Lesions?
Published in Headache (01-01-2014)“…Objective/Background Executive dysfunctions and white matter lesions on magnetic resonance imaging have been reported in migraine. The aim of this study was to…”
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Sex-dependent monoamine oxidase isoforms expression patterns during human brain ageing
Published in Mechanisms of ageing and development (01-07-2021)“…•There are differences in aggressive behavior between males and females.•MAOA is the most investigated genetic factors of aggressive behaviors.•MAOA and MAOB…”
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Fasting and Fast Food Diet Play an Opposite Role in Mice Brain Aging
Published in Molecular neurobiology (01-08-2018)“…Fasting may be exploited as a possible strategy for prevention and treatment of several diseases such as diabetes, obesity, and aging. On the other hand,…”
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Different pediatric brain tumors are associated with different gene expression profiling
Published in Acta histochemica (01-05-2015)“…Malignant brain tumors are the most common pediatric solid tumors and are the leading cause of death from childhood cancers. These tumors include several…”
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