Search Results - "Sandy Pillay"

Higher Dose Oral Fluconazole for the Treatment of AIDS-related Cryptococcal Meningitis (HIFLAC)-report of A5225, a multicentre, phase I/II, two-stage, dose-finding, safety, tolerability and efficacy randomised, amphotericin B-controlled trial of the AIDS Clinical Trials Group by Lalloo, Umesh G, Komarow, Lauren, Aberg, Judith A, Clifford, David B, Hogg, Evelyn, McKhann, Ashley, Bukuru, Aggrey, Lagat, David, Pillay, Sandy, Mave, Vidya, Supparatpinyo, Khuanchai, Samaneka, Wadzanai, Langat, Deborah, Ticona, Eduardo, Badal-Faesen, Sharlaa, Larsen, Robert A

“…The WHO recommended 1200mg/day of fluconazole (FCZ) in the induction phase of cryptococcal meningitis (CM) in HIV prior to 2018 in regions where amphotericin-B…”
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The Medical Education Partnership Initiative (MEPI): Innovations and Lessons for Health Professions Training and Research in Africa by Omaswa, Francis, Kiguli-Malwadde, Elsie, Donkor, Peter, Hakim, James, Derbew, Miliard, Baird, Sarah, Frehywot, Seble, Gachuno, Onesmus Wairumbi, Kamiza, Steve, Kibwage, Isaac Ongubo, Mteta Kien, Alfred, Mulla, Yakub, Mullan, Fitzhugh, Nachega, Jean B, Nkomazana, Oathokwa, Noormohamed, Emilia, Ojoome, Vincent, Olalaye, David, Pillay, Sandy, Sewankambo, Nelson K, De Villiers, Marietjie

“…MEPI was a $130 million competitively awarded grant by President's Emergency Plan for AIDS Relief (PEPFAR) and National Institutes of Health (NIH) to 13…”
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Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study by Shivakoti, Rupak, Gupte, Nikhil, Tripathy, Srikanth, Poongulali, Selvamuthu, Kanyama, Cecilia, Berendes, Sima, Cardoso, Sandra W, Santos, Breno R, La Rosa, Alberto, Mwelase, Noluthando, Pillay, Sandy, Samaneka, Wadzanai, Riviere, Cynthia, Sugandhavesa, Patcharaphan, Bollinger, Robert C, Balagopal, Ashwin, Semba, Richard D, Christian, Parul, Campbell, Thomas B, Gupta, Amita

“…Various individual biomarkers of inflammation and micronutrient status, often correlated with each other, are associated with adverse treatment outcomes in…”
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Concurrent Anemia and Elevated C-Reactive Protein Predicts HIV Clinical Treatment Failure, Including Tuberculosis, After Antiretroviral Therapy Initiation by Shivakoti, Rupak, Yang, Wei-Teng, Gupte, Nikhil, Berendes, Sima, Rosa, Alberto La, Cardoso, Sandra W, Mwelase, Noluthando, Kanyama, Cecilia, Pillay, Sandy, Samaneka, Wadzanai, Riviere, Cynthia, Sugandhavesa, Patcharaphan, Santos, Brento, Poongulali, Selvamuthu, Tripathy, Srikanth, Bollinger, Robert C, Currier, Judith S, Tang, Alice M, Semba, Richard D, Christian, Parul, Campbell, Thomas B, Gupta, Amita

“…Anemia is a known risk factor for clinical failure following antiretroviral therapy (ART). Notably, anemia and inflammation are interrelated, and recent…”
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Medical Education Partnership Initiative gives birth to AFREhealth by Omaswa, Francis, Kiguli-Malwadde, Elsie, Donkor, Peter, Hakim, James, Derbew, Milliard, Baird, Sarah, Frehywot, Seble, Gachuno, Onesmus Wairumbi, Kamiza, Steve, Kibwage, Isaac Ongubo, Mteta, Kein Alfred, Mulla, Yakub, Mullan, Fitzhugh, Nachega, Jean B, Nkomazana, Oathokwa, Noormohamed, Emilia, Ojoome, Vincent, Olalaye, David, Pillay, Sandy, Sewankambo, Nelson K, de Villiers, Marietjie

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Pre-antiretroviral therapy serum selenium concentrations predict WHO stages 3, 4 or death but not virologic failure post-antiretroviral therapy by Shivakoti, Rupak, Gupte, Nikhil, Yang, Wei-Teng, Mwelase, Noluthando, Kanyama, Cecilia, Tang, Alice M, Pillay, Sandy, Samaneka, Wadzanai, Riviere, Cynthia, Berendes, Sima, Lama, Javier R, Cardoso, Sandra W, Sugandhavesa, Patcharaphan, Semba, Richard D, Christian, Parul, Campbell, Thomas B, Gupta, Amita

“…A case-cohort study, within a multi-country trial of antiretroviral therapy (ART) efficacy (Prospective Evaluation of Antiretrovirals in Resource Limited…”
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Predictors of site choice and eventual learning experiences in a decentralised training programme designed to prepare medical students for careers in underserved areas in South Africa by Muzigaba, Moise, Naidoo, Keshena, Ross, Andrew, Nadesan-Reddy, Nisha, Pillay, Sandy

“…Background. There is a dire need for medical schools in South Africa to train medical doctors who have the capacity and willingness to work in primary…”
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Higher Dose Oral Fluconazole for the Treatment of AIDS-related Cryptococcal Meningitis by Lalloo, Umesh G, Komarow, Lauren, Aberg, Judith A, Clifford, David B, Hogg, Evelyn, McKhann, Ashley, Bukuru, Aggrey, Lagat, David, Pillay, Sandy, Mave, Vidya, Supparatpinyo, Khuanchai, Samaneka, Wadzanai, Langat, Deborah, Ticona, Eduardo, Badal-Faesen, Sharlaa, Larsen, Robert A

“…Background The WHO recommended 1200mg/day of fluconazole (FCZ) in the induction phase of cryptococcal meningitis (CM) in HIV prior to 2018 in regions where…”
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Symptom and Viral Rebound in Untreated SARS-CoV-2 Infection by Deo, Rinki, Choudhary, Manish C, Moser, Carlee, Ritz, Justin, Daar, Eric S, Wohl, David A, Greninger, Alexander L, Eron, Joseph J, Currier, Judith S, Hughes, Michael D, Smith, Davey M, Chew, Kara W, Li, Jonathan Z

“…Although symptom and viral rebound have been reported after nirmatrelvir-ritonavir treatment, the trajectories of symptoms and viral load during the natural…”
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Sex-Related Differences in Inflammatory and Immune Activation Markers Before and After Combined Antiretroviral Therapy Initiation by Mathad, Jyoti S, Gupte, Nikhil, Balagopal, Ashwin, Asmuth, David, Hakim, James, Santos, Breno, Riviere, Cynthia, Hosseinipour, Mina, Sugandhavesa, Patcharaphan, Infante, Rosa, Pillay, Sandy, Cardoso, Sandra W, Mwelase, Noluthando, Pawar, Jyoti, Berendes, Sima, Kumarasamy, Nagalingeswaran, Andrade, Bruno B, Campbell, Thomas B, Currier, Judith S, Cohn, Susan E, Gupta, Amita

“…BACKGROUND:Women progress to death at the same rate as men despite lower plasma HIV RNA (viral load). We investigated sex-specific differences in immune…”
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Inflammation and Change in Body Weight With Antiretroviral Therapy Initiation in a Multinational Cohort of HIV-Infected Adults by Mave, Vidya, Erlandson, Kristine M., Gupte, Nikhil, Balagopal, Ashwin, Asmuth, David M., Campbell, Thomas B., Smeaton, Laura, Kumarasamy, Nagalingeswaran, Hakim, James, Santos, Breno, Riviere, Cynthia, Hosseinipour, Mina C., Sugandhavesa, Patcharaphan, Infante, Rosa, Pillay, Sandy, Cardoso, Sandra W., Tripathy, Srikanth, Mwelase, Noluthando, Berendes, Sima, Andrade, Bruno B., Thomas, David L., Bollinger, Robert C., Gupta, Amita

“…Background. Both wasting and obesity are associated with inflammation, but the extent to which body weight changes influence inflammation during human…”
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Viral and symptom rebound following anti-SARS-CoV-2 monoclonal antibody therapy in a randomized placebo-controlled trial by Chew, Kara W, McGinley, Brooke, Moser, Carlee, Li, Jonathan Z, Evering, Teresa H, Ritz, Justin, Javan, Arzhang Cyrus, Margolis, David, Wohl, David A, Hughes, Michael D, Daar, Eric S, Currier, Judith S, Eron, Joseph J, Smith, Davey M

“…We explored viral and symptom rebound after COVID-19 amubarvimab/romlusevimab monoclonal antibody therapy vs placebo in the randomized ACTIV-2/A5401 trial…”
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HIV and COPD: a conspiracy of risk factors by Lalloo, Umesh G., Pillay, Sandy, Mngqibisa, Rosie, Abdool-Gaffar, Sabeer, Ambaram, Anish

“…Chronic obstructive pulmonary disease (COPD) is an under recognized complication of HIV infection. It is estimated that up to 25% of HIV infected people may…”
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Antiretroviral Initiation at ≥800 CD4+ Cells/mm3 Associated With Lower Human Immunodeficiency Virus Reservoir Size by Rasmussen, Thomas A, Ahuja, Sunil K, Kuwanda, Locadiah, Vjecha, Michael J, Hudson, Fleur, Lal, Luxshimi, Rhodes, Ajantha, Chang, Judy, Palmer, Sarah, Auberson-Munderi, Paula, Mugerwa, Henry, Wood, Robin, Badal-Faesen, Sharlaa, Pillay, Sandy, Mngqibisa, Rosie, LaRosa, Alberto, Hildago, Jose, Petoumenos, Kathy, Chiu, Chris, Lutaakome, Joseph, Kitonsa, Jonathan, Kabaswaga, Esther, Pala, Pietro, Ganoza, Carmela, Fisher, Katie, Chang, Christina, Lewin, Sharon R, Wright, Edwina J

“…Abstract Background Identifying factors that determine the frequency of latently infected CD4+ T cells on antiretroviral therapy (ART) may inform strategies…”
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Vitamin A and D Deficiencies Associated With Incident Tuberculosis in HIV-Infected Patients Initiating Antiretroviral Therapy in Multinational Case-Cohort Study by Tenforde, Mark W, Yadav, Ashish, Dowdy, David W, Gupte, Nikhil, Shivakoti, Rupak, Yang, Wei-Teng, Mwelase, Noluthando, Kanyama, Cecilia, Pillay, Sandy, Samaneka, Wadzanai, Santos, Breno, Poongulali, Selvamuthu, Tripathy, Srikanth, Riviere, Cynthia, Berendes, Sima, Lama, Javier R, Cardoso, Sandra W, Sugandhavesa, Patcharaphan, Christian, Parul, Semba, Richard D, Campbell, Thomas B, Gupta, Amita

“…Numerous micronutrients have immunomodulatory roles that may influence risk of tuberculosis (TB), but the association between baseline micronutrient…”
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Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial by Hosseinipour, Mina C, Prof, Bisson, Gregory P, MD, Miyahara, Sachiko, PhD, Sun, Xin, MS, Moses, Agnes, MMED, Riviere, Cynthia, MD, Kirui, Fredrick K, MMED, Badal-Faesen, Sharlaa, MBBCh, Lagat, David, MBChB, Nyirenda, Mulinda, MMED, Naidoo, Kogieleum, MBChB, Hakim, James, Prof, Mugyenyi, Peter, Prof, Henostroza, German, MD, Leger, Paul D, MD, Lama, Javier R, MD, Mohapi, Lerato, MBBCh, Alave, Jorge, MD, Mave, Vidya, MD, Veloso, Valdilea G, MD, Pillay, Sandy, MBChB, Kumarasamy, Nagalingeswaran, PhD, Bao, Jing, MD, Hogg, Evelyn, BA, Jones, Lynne, MT ASCP, Zolopa, Andrew, Prof, Kumwenda, Johnstone, Prof, Gupta, Amita, MD

“…Summary Background Mortality within the first 6 months after initiating antiretroviral therapy is common in resource-limited settings and is often due to…”
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A Strategy for Developing Future Academic Leaders for South Africa in a Resource-Constrained Environment by Lalloo, Umesh G, Bobat, Raziya A, Pillay, Sandy, Wassenaar, Douglas

“…A key challenge in addressing the shortage of health care workers in resource-constrained environments is ensuring that there is optimal academic capacity for…”
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Nevirapine pharmacokinetics in HIV-infected persons receiving rifapentine and isoniazid for TB prevention by Podany, A T, Leon-Cruz, J, Hakim, J, Supparatpinyo, K, Omoz-Oarhe, A, Langat, D, Mwelase, N, Kanyama, C, Gupta, A, Benson, C A, Chaisson, R E, Swindells, S, Fletcher, C V

“…Abstract Background The use of rifamycin antibiotics for TB prevention carries a risk of detrimental drug–drug interactions with concomitantly used ART…”
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HIV Prevention Counseling Intervention Delivered During Routine Clinical Care Reduces HIV Risk Behavior in HIV-Infected South Africans Receiving Antiretroviral Therapy: The Izindlela Zokuphila/Options for Health Randomized Trial by Fisher, Jeffrey D, Cornman, Deborah H, Shuper, Paul A, Christie, Sarah, Pillay, Sandy, Macdonald, Susan, Ngcobo, Ntombenhle, Rivet Amico, K, Lalloo, Umesh, Friedland, Gerald, Fisher, William A

“…CONTEXT:Sustainable interventions are needed to minimize HIV risk behavior among people living with HIV (PLWH) in South Africa on antiretroviral therapy (ART),…”
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Persistently Elevated C-Reactive Protein Level in the First Year of Antiretroviral Therapy, Despite Virologic Suppression, Is Associated With HIV Disease Progression in Resource-Constrained Settings by Shivakoti, Rupak, Yang, Wei-Teng, Berendes, Sima, Mwelase, Noluthando, Kanyama, Cecilia, Pillay, Sandy, Samaneka, Wadzanai, Santos, Breno, Poongulali, Selvamuthu, Tripathy, Srikanth, Riviere, Cynthia, Lama, Javier R., Cardoso, Sandra W., Sugandhavesa, Patcharaphan, Balagopal, Ashwin, Gupte, Nikhil, Semba, Richard D., Campbell, Thomas B., Bollinger, Robert C., Gupta, Amita

“…A case-cohort analysis of human immunodeficiency virus (HIV)–infected individuals receiving antiretroviral therapy (ART) was performed within a multicountry…”
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