Search Results - "Sandy, Martha S."

Cancer Mortality in a Chinese Population Exposed to Hexavalent Chromium in Drinking Water by Beaumont, James J., Sedman, Richard M., Reynolds, Stephen D., Sherman, Claire D., Li, Ling-Hong, Howd, Robert A., Sandy, Martha S., Zeise, Lauren, Alexeeff, George V.

“…Background: In 1987, investigators in Liaoning Province, China, reported that mortality rates for all cancer, stomach cancer, and lung cancer in 1970-1978 were…”
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Improving prediction of chemical carcinogenicity by considering multiple mechanisms and applying toxicogenomic approaches by Guyton, Kathryn Z., Kyle, Amy D., Aubrecht, Jiri, Cogliano, Vincent J., Eastmond, David A., Jackson, Marc, Keshava, Nagalakshmi, Sandy, Martha S., Sonawane, Babasaheb, Zhang, Luoping, Waters, Michael D., Smith, Martyn T.

“…While scientific knowledge of the potential health significance of chemical exposures has grown, experimental methods for predicting the carcinogenicity of…”
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Cannabis Exposure During Critical Windows of Development: Epigenetic and Molecular Pathways Implicated in Neuropsychiatric Disease by Smith, Anna, Kaufman, Farla, Sandy, Martha S., Cardenas, Andres

“…Purpose of Review Cannabis exposure during critical windows of development may have intergenerational physiological consequences disrupting epigenetic…”
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Estimated Cancer Risks Associated with Nitrosamine Contamination in Commonly Used Medications by Li, Kate, Ricker, Karin, Tsai, Feng C., Hsieh, ChingYi J., Osborne, Gwendolyn, Sun, Meng, Marder, M. Elizabeth, Elmore, Sarah, Schmitz, Rose, Sandy, Martha S.

“…Many nitrosamines are potent carcinogens, with more than 30 listed under California’s Proposition 65. Recently, nitrosamine contamination of commonly used…”
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The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them by Smith, Martyn T, Guyton, Kathryn Z, Kleinstreuer, Nicole, Borrel, Alexandre, Cardenas, Andres, Chiu, Weihsueh A, Felsher, Dean W, Gibbons, Catherine F, Goodson, 3rd, William H, Houck, Keith A, Kane, Agnes B, La Merrill, Michele A, Lebrec, Herve, Lowe, Leroy, McHale, Cliona M, Minocherhomji, Sheroy, Rieswijk, Linda, Sandy, Martha S, Sone, Hideko, Wang, Amy, Zhang, Luoping, Zeise, Lauren, Fielden, Mark

“…The key characteristics (KC) of human carcinogens provide a uniform approach to evaluating mechanistic evidence in cancer hazard identification. Refinements to…”
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Application of the Key Characteristics of Carcinogens to Bisphenol A by Ricker, Karin, Cheng, Vanessa, Hsieh, Chingyi Jennifer, Tsai, Feng C., Osborne, Gwendolyn, Li, Kate, Yilmazer-Musa, Meltem, Sandy, Martha S., Cogliano, Vincent J., Schmitz, Rose, Sun, Meng

“…The ten key characteristics (KCs) of carcinogens are based on characteristics of known human carcinogens and encompass many types of endpoints. We propose that…”
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Assessing health risks from multiple environmental stressors: Moving from G×E to I×E by McHale, Cliona M., Osborne, Gwendolyn, Morello-Frosch, Rachel, Salmon, Andrew G., Sandy, Martha S., Solomon, Gina, Zhang, Luoping, Smith, Martyn T., Zeise, Lauren

“…Research on disease causation often attempts to isolate the effects of individual factors, including individual genes or environmental factors. This…”
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Animal evidence considered in determination of cannabis smoke and Δ9‐tetrahydrocannabinol as causing reproductive toxicity (developmental endpoint): Part III. Proposed neurodevelopmental mechanisms of action by Niknam, Yassaman, Iyer, Poorni, Campbell, Marlissa A., Moran, Francisco, Sandy, Martha S., Zeise, Lauren

“…This review summarizes the most common potential pathways of neurodevelopmental toxicity due to perinatal exposure to Δ9‐tetrahydrocannabinol (Δ9‐THC) that…”
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Cancer Hazard Identification Integrating Human Variability: The Case of Coumarin by Hsieh, ChingYi Jennifer, Sun, Meng, Osborne, Gwendolyn, Ricker, Karin, Tsai, Feng C., Li, Kate, Tomar, Rajpal, Phuong, Jimmy, Schmitz, Rose, Sandy, Martha S.

“…Coumarin is a naturally occurring sweet-smelling benzopyrone that may be extracted from plants or synthesized for commercial uses. Its uses include as a…”
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Carcinogenicity of some aromatic amines and related compounds by DeMarini, David M., Carreón-Valencia, Tania, Gwinn, William M., Hopf, Nancy B., Sandy, Martha S., Bahadori, Tina, Calaf, Gloria M., Chen, Guosheng, de Conti, Aline, Fritschi, Lin, Gi, Min, Josephy, P. David, Kirkeleit, Jorunn, Kjaerheim, Kristina, Langouët, Sophie, McElvenny, Damien M., Sergi, Consolato M., Stayner, Leslie T., Toyoda, Takeshi, Grosse, Yann, Benbrahim-Tallaa, Lamia, El Ghissassi, Fatiha, Suonio, Eero, Turner, Michelle C., Cree, Ian A., Mattock, Heidi, Müller, Karen, Chung, Felicia, Guyton, Kathryn Z., Schubauer-Berigan, Mary K.

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Animal evidence considered in determination of cannabis smoke and Δ9‐tetrahydrocannabinol as causing reproductive toxicity (developmental endpoint); Part I. Somatic development by Campbell, Marlissa A., Iyer, Poorni, Kaufman, Farla, Kim, Allegra, Moran, Francisco, Niknam, Yassaman, Wu, Lily, Sandy, Martha S., Zeise, Lauren

“…Objectives On December 11, 2019, California's Developmental and Reproductive Toxicant Identification Committee (DARTIC) met to consider the addition of…”
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Response to “Comment on Coumarin Hazard Identification” by Hsieh, ChingYi Jennifer, Sun, Meng, Osborne, Gwendolyn, Ricker, Karin, Tsai, Feng C., Li, Kate, Tomar, Rajpal, Phuong, Jimmy, Schmitz, Rose, Sandy, Martha S.

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Chromium(VI) Ingestion and Cancer by Beaumont, James J, Sedman, Richard M, Sandy, Martha S, Zeise, Lauren, Reynolds, Stephen D

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Titanium Dioxide and Lung Cancer by Beaumont, James J., Sandy, Martha S., Sherman, Claire D.

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Animal evidence considered in determination of cannabis smoke and Δ 9 ‐tetrahydrocannabinol as causing reproductive toxicity (developmental endpoint): Part III . Proposed neurodevelopmental mechanisms of action by Niknam, Yassaman, Iyer, Poorni, Campbell, Marlissa A., Moran, Francisco, Sandy, Martha S., Zeise, Lauren

“…Abstract This review summarizes the most common potential pathways of neurodevelopmental toxicity due to perinatal exposure to Δ 9 ‐tetrahydrocannabinol (Δ 9…”
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Animal evidence considered in determination of cannabis smoke and Δ 9 ‐tetrahydrocannabinol as causing reproductive toxicity (developmental endpoint); Part I. Somatic development by Campbell, Marlissa A., Iyer, Poorni, Kaufman, Farla, Kim, Allegra, Moran, Francisco, Niknam, Yassaman, Wu, Lily, Sandy, Martha S., Zeise, Lauren

“…Abstract Objectives On December 11, 2019, California's Developmental and Reproductive Toxicant Identification Committee (DARTIC) met to consider the addition…”
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Comparative studies on the mechanisms of paraquat and 1-methyl-4-phenylpyridine (MPP+) cytotoxicity by Di Monte, D, Sandy, M S, Ekström, G, Smith, M T

“…1-methyl-4-phenylpyridine (MPP+) is the putative toxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and is structurally similar to the…”
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Genotypic Analysis of Mutations in Taq I Restriction Recognition Sites by Restriction Fragment Length Polymorphism/Polymerase Chain Reaction by Sandy, Martha S., Chiocca, Susanna M., Cerutti, Peter A.

“…Point mutations in somatic cells play a role in the etiology of several classes of human pathologies. Experimental procedures are required that allow the…”
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Genotypic analysis of N-ethyl-N-nitrosourea-induced mutations by Taq I restriction fragment length polymorphism/polymerase chain reaction in the c-H-ras1 gene by CHIOCCA, S. M, SANDY, M. S, CERUTTI, P. A

“…In genotypic mutation analysis DNA sequence changes are determined without the in vivo or in vitro selection of phenotypically altered cells. We have studied…”
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PCR analysis of platelet mtDNA: lack of specific changes in Parkinson's disease by Sandy, M S, Langston, J W, Smith, M T, Di Monte, D A

“…An alteration within the mitochondrial DNA (mtDNA) has been hypothesized to underlie the deficiencies in mitochondrial complex I activity observed in the…”
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