Performance of the Abbott ID NOW rapid SARS-CoV-2 amplification assay in relation to nasopharyngeal viral RNA loads

•Calibration of the Xpert with viral stock dilutions was linear and reproducible.•Overall Xpert/ID-NOW positive agreement = 70% and negative agreement = 99.6%.•Sensitivity of ID-NOW for Xpert N2 CT ≤ 37 (viral loads ≥ 945 copies/mL) was 100%.•Sensitivity of ID-NOW for Xpert N2 for N2 CT > 37 was...

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Bibliographic Details
Published in:	Journal of clinical virology Vol. 140; p. 104843
Main Authors:	Sepulveda, Jorge L., Abdulbaki, Rami, Sands, Zachary, Codoy, Maria, Mendoza, Salome, Isaacson, Nancy, Kochar, Olga, Keiser, John, Haile-Mariam, Tenagne, Meltzer, Andrew C., Mores, Christopher N., Sepulveda, Antonia R.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-07-2021
Subjects:	Abbott ID NOW Clinical Laboratory Techniques COVID-19 COVID-19 - diagnosis COVID-19 Nucleic Acid Testing Humans Laboratory utilization Nasopharynx - virology Rapid testing RNA, Viral - isolation & purification SARS-CoV-2 SARS-CoV-2 - isolation & purification Sensitivity Sensitivity and Specificity Viral Load COVID-19 Rapid testing SARS-CoV-2 Sensitivity Laboratory utilization Abbott ID NOW
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Summary:	•Calibration of the Xpert with viral stock dilutions was linear and reproducible.•Overall Xpert/ID-NOW positive agreement = 70% and negative agreement = 99.6%.•Sensitivity of ID-NOW for Xpert N2 CT ≤ 37 (viral loads ≥ 945 copies/mL) was 100%.•Sensitivity of ID-NOW for Xpert N2 for N2 CT > 37 was only 37.7%.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1386-6532 1873-5967 1873-5967
DOI:	10.1016/j.jcv.2021.104843