Search Results - "Sands, Scott A"

The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study by Azarbarzin, Ali, Sands, Scott A, Stone, Katie L, Taranto-Montemurro, Luigi, Messineo, Ludovico, Terrill, Philip I, Ancoli-Israel, Sonia, Ensrud, Kristine, Purcell, Shaun, White, David P, Redline, Susan, Wellman, Andrew

“…Abstract Aims Apnoea–hypopnoea index (AHI), the universal clinical metric of sleep apnoea severity, poorly predicts the adverse outcomes of sleep apnoea,…”
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The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial by Taranto-Montemurro, Luigi, Messineo, Ludovico, Sands, Scott A, Azarbarzin, Ali, Marques, Melania, Edwards, Bradley A, Eckert, Danny J, White, David P, Wellman, Andrew

“…There is currently no effective pharmacological treatment for obstructive sleep apnea (OSA). Recent investigations indicate that drugs with noradrenergic and…”
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More Than the Sum of the Respiratory Events: Personalized Medicine Approaches for Obstructive Sleep Apnea by Edwards, Bradley A, Redline, Susan, Sands, Scott A, Owens, Robert L

“…Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined by the apnea-hypopnea index (AHI). Continuous positive airway…”
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The Sleep Apnea-Specific Hypoxic Burden Predicts Incident Heart Failure by Azarbarzin, Ali, Sands, Scott A., Taranto-Montemurro, Luigi, Vena, Daniel, Sofer, Tamar, Kim, Sang-Wook, Stone, Katie L., White, David P., Wellman, Andrew, Redline, Susan

“…Heart failure (HF) is a leading cause of morbidity and mortality and although it is linked to sleep apnea, which physiological stressors most strongly…”
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Effects of the Combination of Atomoxetine and Oxybutynin on OSA Endotypic Traits by Taranto-Montemurro, Luigi, Messineo, Ludovico, Azarbarzin, Ali, Vena, Daniel, Hess, Lauren B., Calianese, Nicole A., White, David P., Wellman, Andrew, Sands, Scott A.

“…We recently showed that administration of the combination of the noradrenergic drug atomoxetine plus the antimuscarinic oxybutynin (ato-oxy) prior to sleep…”
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Pathogenesis of central and complex sleep apnoea by Orr, Jeremy E., Malhotra, Atul, Sands, Scott A.

“…ABSTRACT Central sleep apnoea (CSA) – the temporary absence or diminution of ventilatory effort during sleep – is seen in a variety of forms including periodic…”
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Quantifying the Arousal Threshold Using Polysomnography in Obstructive Sleep Apnea by Sands, Scott A, Terrill, Philip I, Edwards, Bradley A, Taranto Montemurro, Luigi, Azarbarzin, Ali, Marques, Melania, de Melo, Camila M, Loring, Stephen H, Butler, James P, White, David P, Wellman, Andrew

“…Abstract Study Objectives Precision medicine for obstructive sleep apnea (OSA) requires noninvasive estimates of each patient’s pathophysiological “traits.”…”
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Obstructive sleep apnea in older adults is a distinctly different physiological phenotype by Edwards, Bradley A, Wellman, Andrew, Sands, Scott A, Owens, Robert L, Eckert, Danny J, White, David P, Malhotra, Atul

“…Current evidence suggests that the pathological mechanisms underlying obstructive sleep apnea (OSA) are altered with age. However, previous studies examining…”
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Assessing the Physiologic Endotypes Responsible for REM- and NREM-Based OSA by Joosten, Simon A., Landry, Shane A., Wong, Ai-Ming, Mann, Dwayne L., Terrill, Philip I., Sands, Scott A., Turton, Anthony, Beatty, Caroline, Thomson, Luke, Hamilton, Garun S., Edwards, Bradley A.

“…Patients with OSA can have the majority of their respiratory events in rapid eye movement (REM) sleep or in non-rapid eye movement (NREM) sleep. No previous…”
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Insulin Resistance, Hyperglycemia, and Risk of Developing Obstructive Sleep Apnea in Men and Women in the United States by Huang, Tianyi, Sands, Scott A, Stampfer, Meir J, Tworoger, Shelley S, Hu, Frank B, Redline, Susan

“…Recent prospective studies suggest diabetes as a risk factor for the development of obstructive sleep apnea (OSA). However, the extent to which…”
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Breath-holding as a novel approach to risk stratification in COVID-19 by Messineo, Ludovico, Perger, Elisa, Corda, Luciano, Joosten, Simon A, Fanfulla, Francesco, Pedroni, Leonardo, Terrill, Philip I, Lombardi, Carolina, Wellman, Andrew, Hamilton, Garun S, Malhotra, Atul, Vailati, Guido, Parati, Gianfranco, Sands, Scott A

“…Despite considerable progress, it remains unclear why some patients admitted for COVID-19 develop adverse outcomes while others recover spontaneously. Clues…”
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Maturation of heart rate and blood pressure variability during sleep in term-born infants by Yiallourou, Stephanie R, Sands, Scott A, Walker, Adrian M, Horne, Rosemary S C

“…Abnormal blood pressure control is implicated in the sudden infant death syndrome (SIDS). However, no data exist on normal development of blood pressure…”
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The development of autonomic cardiovascular control is altered by preterm birth by Yiallourou, Stephanie R, Witcombe, Nicole B, Sands, Scott A, Walker, Adrian M, Horne, Rosemary S.C

“…Abstract Objectives Autonomic dysfunction, either sympathetic or parasympathetic, may explain the increased incidence of Sudden Infant Death Syndrome (SIDS)…”
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Association of Periodic Limb Movements and Obstructive Sleep Apnea With Risk of Cardiovascular Disease and Mortality by Zinchuk, Andrey, Srivali, Narat, Qin, Li, Jeon, Sangchoon, Ibrahim, Ahmad, Sands, Scott A, Koo, Brian, Yaggi, Henry K

“…Obstructive sleep apnea is a well-established risk factor for cardiovascular disease (CVD). Recent studies have also linked periodic limb movements during…”
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EPA and DHA in blood cell membranes from acute coronary syndrome patients and controls by Block, Robert C, Harris, William S, Reid, Kimberly J, Sands, Scott A, Spertus, John A

“…Abstract Background Increased blood levels of the omega-3 fatty acids (FA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been inversely…”
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Maternal Docosahexaenoic Acid Exposure Needed to Achieve Maternal-Newborn EQ by Christifano, Danielle N, Gustafson, Kathleen M, Carlson, Susan E, Sultanna, Nasrin, Brown, Alexandra, Sands, Scott A, Colombo, John, Gajewski, Byron J

“…Achieving maternal docosahexaenoic acid (DHA) status equal to or greater than the infant's DHA status at delivery is known as maternal-newborn DHA equilibrium…”
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Higher-Dose DHA Supplementation Modulates Immune Responses in Pregnancy and Is Associated with Decreased Preterm Birth by Valentine, Christina J, Khan, Aiman Q, Brown, Alexandra R, Sands, Scott A, Defranco, Emily A, Gajewski, Byron J, Carlson, Susan E, Reber, Kristina M, Rogers, Lynette K

“…Pregnancy and parturition involve extensive changes in the maternal immune system. In our randomized, multi-site, double-blind superiority trial using a…”
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Acetazolamide as an Add-on Therapy Following Barbed Reposition Pharyngoplasty in Obstructive Sleep Apnea: A Randomized Controlled Trial by Hellemans, Simon, Van de Perck, Eli, Van Loo, Dorine, Verbraecken, Johan, Sands, Scott A, Azarbarzin, Ali, Dieltjens, Marijke, Op De Beeck, Sara, Vroegop, Anneclaire, Vanderveken, Olivier M

“…Surgical interventions, like barbed reposition pharyngoplasty (BRP), are a valuable alternative for patients with obstructive sleep apnea (OSA) who are unable…”
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Respiratory system reactance is an independent determinant of asthma control by Kelly, Vanessa J, Sands, Scott A, Harris, R Scott, Venegas, Jose G, Brown, Nathan J, Stuart-Andrews, Christopher R, King, Gregory G, Thompson, Bruce R

“…The mechanisms underlying not well-controlled (NWC) asthma remain poorly understood, but accumulating evidence points to peripheral airway dysfunction as a key…”
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Angiotensin II-Type I Receptor Antagonism Does Not Influence the Chemoreceptor Reflex or Hypoxia-Induced Central Sleep Apnea in Men by Brown, Courtney V, Boulet, Lindsey M, Vermeulen, Tyler D, Sands, Scott A, Wilson, Richard J A, Ayas, Najib T, Floras, John S, Foster, Glen E

“…Components of the renin-angiotensin system (RAS) situated within the carotid body or central nervous system may promote hypoxia-induced chemoreceptor reflex…”
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