Search Results - "Sandrock, I"

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells by Flotho, C, Claus, R, Batz, C, Schneider, M, Sandrock, I, Ihde, S, Plass, C, Niemeyer, C M, Lübbert, M

“…The three DNA methyltransferase (DNMT)-inhibiting cytosine nucleoside analogues, azacitidine, decitabine and zebularine, which are currently studied as…”
Get full text

Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3 by Ronkina, N., Schuster-Gossler, K., Hansmann, F., Kunze-Schumacher, H., Sandrock, I., Yakovleva, T., Lafera, J., Baumgärtner, W., Krueger, A., Prinz, I., Gossler, A., Kotlyarov, A., Gaestel, M.

“…Mitogen-activated protein kinase 6/extracellular signal-regulated kinase 3 (MAPK6/ERK3) is an atypical member of the MAPKs. An essential role has been…”
Get full text

γδT Cells Are Essential for Orthodontic Tooth Movement by Wald, S., Leibowitz, A., Aizenbud, Y., Saba, Y., Zubeidat, K., Barel, O., Koren, N., Heyman, O., Wilharm, A., Sandrock, I., Fleissig, O., Tal, Y., Prinz, I., Aizenbud, D., Chaushu, S., Hovav, A.H.

“…Sustained mechanical forces applied to tissue are known to shape local immunity. In the oral mucosa, mechanical stress, either naturally induced by masticatory…”
Get full text

Association of HAX1 deficiency with neurological disorder by Rezaei, N, Chavoshzadeh, Z, R Alaei, O, Sandrock, I, Klein, C

“…Severe congenital neutropenia (SCN) is a rare, heterogeneous, primary immunodeficiency disorder characterized by early onset of severe bacterial infections. We…”
Get more information

Large granular lymphocyte proliferation and revertant mosaicism: two rare events in a Wiskott-Aldrich syndrome patient by Boztug, K, Baumann, U, Ballmaier, M, Webster, D, Sandrock, I, Jacobs, R, Lion, T, Preuner, S, Germeshausen, M, Hansen, G, Welte, K, Klein, C

“…1 Department of Pediatric Hematology and Oncology, Hannover Medical School, Carl-Neuberg-Straße 1, D-30625 Hannover, Germany 2 Department of Pediatric…”
Get full text

Development of Interleukin-17-Producing gamma delta T Cells Is Restricted to a Functional Embryonic Wave by Haas, J D, Ravens, S, Dueber, S, Sandrock, I, Oberdoerfer, L, Kashani, E, Chennupati, V, Foehse, L, Naumann, R, Weiss, S, Krueger, A, Foerster, R, Prinz, I

“…gamma delta T cells are an important innate source of interleukin-17 (IL-17). In contrast to T helper 17 (Th17) cell differentiation, which occurs in the…”
Get full text

Mutual interplay between IL-17–producing γδT cells and microbiota orchestrates oral mucosal homeostasis by Wilharm, Anneke, Tabib, Yaara, Nassar, Maria, Reinhardt, Annika, Mizraji, Gabriel, Sandrock, Inga, Heyman, Oded, Barros-Martins, Joana, Aizenbud, Yuval, Khalaileh, Abed, Eli-Berchoer, Luba, Elinav, Eran, Wilensky, Asaf, Förster, Reinhold, Bercovier, Herve, Prinz, Immo, Hovav, Avi-Hai

“…γδT cells are a major component of epithelial tissues and play a role in tissue homeostasis and host defense. γδT cells also reside in the gingiva, an oral…”
Get full text

Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance by Wilharm, Anneke, Cristiano Brigas, Maria Helena, Sandrock, Inga, Ribeiro, Miguel, Amado, Tiago, Reinhardt, Annika, Demera, Abdi, Hoenicke, Lisa, Strowig, Till, Carvalho, Tânia, Prinz, Immo, Ribot, Julie Cécile Caroline

“…© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
Get full text

HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease) by Dahl, Niklas, Appaswamy, Giridharan, Schwinzer, Beate, Melin, Malin, Henter, Jan-Inge, Rathinam, Chozhavendan, Germeshausen, Manuela, Fadeel, Bengt, Bohn, Georg, Zeidler, Cornelia, Welte, Karl, Rezaei, Nima, Boztug, Kaan, Grimbacher, Bodo, Sandrock, Inga, Palmblad, Jan, Klein, Christoph, Schäffer, Alejandro A, Grudzien, Magda, Carlsson, Göran

“…Autosomal recessive severe congenital neutropenia (SCN) constitutes a primary immunodeficiency syndrome associated with increased apoptosis in myeloid cells,…”
Get full text

Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes by You, Yuanyuan, Dunst, Josefine, Ye, Kewei, Sandoz, Patrick A., Reinhardt, Annika, Sandrock, Inga, Comet, Natalia R., Sarkar, Rupak Dey, Yang, Emily, Duprez, Estelle, Agudo, Judith, Brown, Brian D., Utz, Paul J., Kastenmüller, Wolfgang, Gerlach, Carmen, Prinz, Immo, Önfelt, Björn, Kreslavsky, Taras

“…Upregulation of diverse self-antigens that constitute components of the inflammatory response overlaps spatially and temporally with the emergence of…”
Get full text

Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice by Bertram, Tabea, Reimers, Daniel, Lory, Niels C, Schmidt, Constantin, Schmid, Joanna, C Heinig, Lisa, Bradtke, Peter, Rattay, Guido, Zielinski, Stephanie, Hellmig, Malte, Bartsch, Patricia, Rohde, Holger, Nuñez, Sarah, Rosemblatt, Mariana V, Bono, Maria Rosa, Gagliani, Nicola, Sandrock, Inga, Panzer, Ulf, Krebs, Christian F, Meyer-Schwesinger, Catherine, Prinz, Immo, Mittrücker, Hans-Willi

“…γδ T cells are involved in the control of infection, but their importance in protection compared to other T cells is unclear. We used a mouse model of systemic…”
Get full text

Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells by Sandrock, Inga, Reinhardt, Annika, Ravens, Sarina, Binz, Christoph, Wilharm, Anneke, Martins, Joana, Oberdörfer, Linda, Tan, Likai, Lienenklaus, Stefan, Zhang, Baojun, Naumann, Ronald, Zhuang, Yuan, Krueger, Andreas, Förster, Reinhold, Prinz, Immo

“…γδ T cells are highly conserved in jawed vertebrates, suggesting an essential role in the immune system. However, γδ T cell-deficient mice display surprisingly…”
Get full text

Correction: Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance by Wilharm, Anneke, Brigas, Helena C., Sandrock, Inga, Ribeiro, Miguel, Amado, Tiago, Reinhardt, Annika, Demera, Abdi, Hoenicke, Lisa, Strowig, Till, Carvalho, Tânia, Prinz, Immo, Ribot, Julie C.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

γδT Cells Are Essential for Orthodontic Tooth Movement by Wald, S, Leibowitz, A, Aizenbud, Y, Saba, Y, Zubeidat, K, Barel, O, Koren, N, Heyman, O, Wilharm, A, Sandrock, I, Fleissig, O, Tal, Y, Prinz, I, Aizenbud, D, Chaushu, S, Hovav, A H

“…Sustained mechanical forces applied to tissue are known to shape local immunity. In the oral mucosa, mechanical stress, either naturally induced by masticatory…”
Get full text