Search Results - "Sandrim, Valéria C."

Potential roles of visfatin/NAMPT on endothelial dysfunction in preeclampsia and pathways underlying cardiac and vascular remodeling by Ceron, Carla S., Pereira, Daniela A., Sandrim, Valéria C., Luizon, Marcelo R.

Get full text

Circulating levels of tissue inhibitor of metalloproteinase 3, a protein with inhibitory effects on angiogenesis, are increased in pre‐eclampsia by Palei, Ana C., Cruz, Juliana de O., Chaguri, João Leandro, Peraçoli, José Carlos, Romão‐Veiga, Mariana, Ribeiro‐Vasques, Vanessa R., Cavalli, Ricardo C., Nunes, Priscila R., Luizon, Marcelo R., Sandrim, Valéria C.

“…Objective To assess and compare circulating tissue inhibitor of metalloproteinase 3 (TIMP‐3) concentrations between women with pre‐eclampsia and healthy…”
Get full text

Resveratrol improves endothelial cell markers impaired by plasma incubation from women who subsequently develop preeclampsia by Caldeira-Dias, Mayara, Montenegro, Marcelo F, Bettiol, Heloisa, Barbieri, Marco Antonio, Cardoso, Viviane C, Cavalli, Ricardo C, Sandrim, Valéria C

“…In this study, we demonstrated that plasma collected from women who subsequently developed preeclampsia caused increased heme oxygenase-1 (HO-1) production and…”
Get full text

Amino Acid Biosignature in Plasma among Ischemic Stroke Subtypes by Resende, Rodrigo R., Pinto, Mauro C. X., Paiva, Maria J. N., Cardeal, Zenilda L., Menezes, Helvécio C., Mendes, Thiago O., Sena, Marcelo M., Goulart, Vânia A. M., Sandrim, Valéria C.

“…Ischemic stroke is a neurovascular disorder caused by reduced or blockage of blood flow to the brain, which may permanently affect motor and cognitive…”
Get full text

Higher levels of circulating TIMP-4 in preeclampsia is strongly associated with clinical parameters and microRNA by Sandrim, Valéria C., Diniz, Solange, Eleuterio, Nibia Mariana, Gomes, Karina B., Dusse, Luci Maria S., Cavalli, Ricardo C.

“…Background: Preeclampsia results in maternal and fetal complications and some studies have reported the role of MMPs and TIMPs in its pathophysiology…”
Get full text

Polymorphisms in endothelial nitric oxide synthase gene in early and late severe preeclampsia by Alpoim, Patrícia Nessralla, Gomes, Karina Braga, Pinheiro, Melina de Barros, Godoi, Lara Carvalho, Jardim, Letícia Lemos, Muniz, Ludmila Gomes, Sandrim, Valéria C., Fernandes, Ana Paula, Dusse, Luci Maria S.

“…•NO pathway seems to play a central role in uteroplacental changes during pregnancy.•Preeclampsia (PE) is associated with endothelial dysfunction.•Polymorphism…”
Get full text

4G/5G polymorphism modulates PAI-1 circulating levels in obese women by Fernandes, Karla S., Sandrim, Valéria C.

“…The increase in plasminogen activator inhibitor type 1 (PAI-1) has been described as a risk factor to thrombosis-related diseases. In addition, it has been…”
Get full text

Endogenous nitric oxide formation correlates negatively with circulating matrix metalloproteinase (MMP)-2 and MMP-9 levels in black subjects by Metzger, Ingrid F., Sandrim, Valéria C., Tanus-Santos, Jose E.

“…Deficient formation of endogenous nitric oxide (NO) contributes to cardiovascular diseases, and this may be associated with increased circulating levels of…”
Get full text

Antihypertensive therapy in pre-eclampsia: effects of plasma from nonresponsive patients on endothelial gene expression by Luizon, Marcelo R, Caldeira-Dias, Mayara, Deffune, Elenice, Fernandes, Karla S, Cavalli, Ricardo C, Tanus-Santos, José E, Sandrim, Valéria C

“…Over 40% of patients with pre-eclampsia are nonresponsive to antihypertensive therapy, but the underlying mechanisms are unknown. We examined the effects of…”
Get full text

Preeclamptic plasma stimulates the expression of miRNAs, leading to a decrease in endothelin-1 production in endothelial cells by Caldeira-Dias, Mayara, Luizon, Marcelo R., Deffune, Elenice, Tanus-Santos, Jose E., Freire, Paula P., Carvalho, Robson F., Bettiol, Heloisa, Cardoso, Viviane C., Antonio Barbieri, Marco, Cavalli, Ricardo C., Sandrim, Valéria C.

“…•In vitro endothelin-1 levels are increased before onset of preeclampsia symptoms.•In vitro endothelin-1 levels are similar after onset of preeclampsia…”
Get full text

NAMPT levels are inversely related to nitric oxide formation and positively related to soluble fms-like tyrosine kinase-1 levels in preeclampsia by Pereira, Daniela A., Sandrim, Valéria C., Palei, Ana C.T., Tanus-Santos, Jose E., Belo, Vanessa A., Cavalli, Ricardo C., Luizon, Marcelo R.

“…•Plasma NAMPT and nitrite levels are positively related in healthy pregnant.•Plasma NAMPT and nitrite levels are inversely related in preeclampsia.•Plasma…”
Get full text

Homocysteine and nitrite levels are modulated by MTHFR 677C>T polymorphism in obese women treated with simvastatin by Villela, Maria P, Andrade, Vanessa L, Eccard, Bryelle, Jordão, Alceu A, Sertório, Jonas T, Tanus-Santos, Jose E, Silva, Ieda FO, Silveira, Josianne N, Sandrim, Valéria C

“…Summary Higher homocysteine (Hcy) levels are associated with cardiovascular risk. The aim of the present study was to evaluate the effect of simvastatin…”
Get full text

Anti-inflammatory effects of atorvastatin: Modulation by the T-786C polymorphism in the endothelial nitric oxide synthase gene by Souza-Costa, Débora C, Sandrim, Valéria C, Lopes, Lívia F, Gerlach, Raquel F, Rego, Eduardo M, Tanus-Santos, Jose E

“…Abstract Statins produce cholesterol-independent, anti-inflammatory effects, which result at least in part from increased endothelial nitric oxide production…”
Get full text

Endothelial nitric oxide synthase haplotypes affect the susceptibility to hypertension in patients with type 2 diabetes mellitus by Sandrim, Valéria C., de Syllos, Roger W.C., Lisboa, Hugo R.K., Tres, Glaucia S., Tanus-Santos, Jose E.

“…Type 2 diabetes mellitus (T2DM) and hypertension (HT) commonly coexist. While endothelial nitric oxide synthase (eNOS) haplotypes have been associated with HT,…”
Get full text

Endothelial nitric oxide synthase haplotypes are related to blood pressure elevation, but not to resistance to antihypertensive drug therapy by Sandrim, Valéria C, Yugar-Toledo, Juan C, Desta, Zeruesenay, Flockhart, David A, Moreno, Heitor, Tanus-Santos, Jose E

“…OBJECTIVESMost hypertensive patients require two or more drugs to control arterial blood pressure effectively. Although endothelial nitric oxide synthase…”
Get full text

Effect of acetylsalicylic acid on platelet activation and oxidative profile in a set of Brazilian patients with type 2 diabetes mellitus by Duarte, Rita C.F, Gonçalves, Líllian H, Campos, Fernanda M.F, Filho, Olindo A.M, Alves, Michelle T, Fernandes, Ana P, Borges, Karina B.G, Dusse, Luci M.S, Faria, Mayara C, Gonçalves, Gisele S, Bosco, Adriana A, Sandrim, Valéria C, Carvalho, Maria G

“…Type 2 diabetes mellitus (DM2) is a metabolic disorder associated with hyperactivation of platelets, increased formation of platelet microparticles (PMPs) and…”
Get full text

Visfatin levels are decreased in advanced stages of diabetic nephropathy by Rodrigues, Kathryna F, Pietrani, Nathália T, Bosco, Adriana A, Ferreira, Cláudia N, Sandrim, Valéria C, Gomes, Karina B

Get more information

Different Proteomic Profiles Regarding Antihypertensive Therapy in Preeclampsia Pregnant by Pinto-Souza, Caroline C, Kaihara, Julyane N S, Nunes, Priscila R, Mastella, Moises H, Rossini, Bruno C, Cavecci-Mendonça, Bruna, Cavalli, Ricardo de Carvalho, Dos Santos, Lucilene D, Sandrim, Valeria C

“…Preeclampsia (PE) is a hypertensive pregnancy syndrome associated with target organ damage and increased cardiovascular risks, necessitating antihypertensive…”
Get full text

Circulating Total Cell-Free DNA Levels Are Increased in Hypertensive Disorders of Pregnancy and Associated with Prohypertensive Factors and Adverse Clinical Outcomes by Amaral, Lorena M, Sandrim, Valeria C, Kutcher, Matthew E, Spradley, Frank T, Cavalli, Ricardo C, Tanus-Santos, Jose E, Palei, Ana C

“…Previous studies have described increased circulating cell-free DNA (cfDNA) in hypertensive disorders of pregnancy (HDP). Here, we aimed first to confirm this…”
Get full text

Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene-Gene Interactions by Luizon, Marcelo R, Pereira, Daniela A, Sandrim, Valeria C

“…Hypertension is a leading cause of cardiovascular mortality, but only about half of patients on antihypertensive therapy achieve blood pressure control…”
Get full text