Search Results - "Sandoz, A"
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Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux
Published in PLoS biology (01-12-2019)“…Holo-tomographic microscopy (HTM) is a label-free microscopy method reporting the fine changes of a cell's refractive indices (RIs) in three dimensions at high…”
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Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
Published in Nature chemical biology (01-04-2021)“…Many biochemical reactions require controlled recruitment of proteins to membranes. This is largely regulated by posttranslational modifications. A frequent…”
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3
Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
Published in Nature communications (23-01-2018)“…The reversible modification of cysteine residues by thioester formation with palmitate ( S -palmitoylation) is an abundant lipid post-translational…”
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4
Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging
Published in Nature communications (18-12-2014)“…Super-resolution optical fluctuation imaging (SOFI) provides an elegant way of overcoming the diffraction limit in all three spatial dimensions by computing…”
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5
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
Published in Nature communications (27-09-2023)“…γδ T cells play a pivotal role in protection against various types of infections and tumours, from early childhood on and throughout life. They consist of…”
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Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade
Published in eLife (15-08-2017)“…S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we…”
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Dynamics of CLIMP-63 S-acylation control ER morphology
Published in Nature communications (17-01-2023)“…The complex architecture of the endoplasmic reticulum (ER) comprises distinct dynamic features, many at the nanoscale, that enable the coexistence of the…”
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Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin
Published in PLoS computational biology (01-02-2016)“…Cellular functions are largely regulated by reversible post-translational modifications of proteins which act as switches. Amongst these, S-palmitoylation is…”
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How many lives does CLIMP-63 have?
Published in Biochemical Society transactions (01-04-2015)“…In 1995, in the Biochemical Society Transactions, Mundy published the first review on CLIMP-63 (cytoskeleton-linking membrane protein 63) or CKPA4…”
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Assessment of the in vitro barrier integrity by in vitro TEER measurement for toxicology screening
Published in Toxicology letters (01-10-2015)Get full text
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11
Recognition of synthetic polyanionic ligands underlies “spontaneous” reactivity of Vγ1 γδTCRs
Published in Journal of leukocyte biology (01-06-2020)“…Although γδTCRs were discovered more than 30 yr ago, principles of antigen recognition by these receptors remain unclear and the nature of these antigens is…”
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A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding
Published in Angewandte Chemie International Edition (14-10-2019)“…The development of a fluorescent LCK inhibitor that exhibits favourable solvatochromic properties upon binding the kinase is described. Fluorescent properties…”
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13
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes
Published in Nature immunology (2024)“…Upregulation of diverse self-antigens that constitute components of the inflammatory response overlaps spatially and temporally with the emergence of…”
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The evolution of two great Mediterranean Deltas: Remote sensing to visualize the evolution of habitats and land use in the Gediz and Rhone Deltas
Published in Ocean & coastal management (01-12-2012)“…Land cover and land cover change, both in time and space, were analyzed in the Gediz Delta (Turkey) and the Rhone Delta (Camargue, France) to determine the…”
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15
Health providers induced iatrogenic delusions of infestation
Published in Clinical, cosmetic and investigational dermatology (01-09-2019)“…Patients that suffer from factitial dermatosis mutilate their skin, often lacking any consciousness of self-injury, attributing the resulting lesions to…”
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Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip
Published in Cell reports methods (18-07-2022)“…Here, we present a methodology based on multiplexed fluorescence screening of two- or three-dimensional cell cultures in a newly designed multichambered…”
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17
Remote sensing based identification of environmental risk factors associated with West Nile disease in horses in Camargue, France
Published in Preventive veterinary medicine (16-04-2007)“…Geographic information system and remote sensing technologies were used to identify landscape features associated with risk of West Nile virus transmission as…”
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Glass eel recruitment, Anguilla anguilla (L.), in a Mediterranean lagoon assessed by a glass eel trap: factors explaining the catches
Published in Hydrobiologia (01-05-2008)“…Although the colonisation of coastal rivers on the Atlantic and Mediterranean coast by glass eels, Anguilla anguilla, has been well studied and understood, the…”
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Journal Article Conference Proceeding -
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Ractopamine in particulate matter emitted from beef cattle feedyards and playa wetlands in the Central Plains
Published in Environmental toxicology and chemistry (01-04-2018)“…Beef cattle in the United States are routinely administered ractopamine, a β‐adrenergic receptor agonist, to enhance growth. The present study is the first to…”
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Integrated hydrological modelling of a managed coastal Mediterranean wetland (Rhone delta, France): initial calibration
Published in Hydrology and earth system sciences (2003)“…This paper presents a model of a heavily managed coastal Mediterranean wetland. The hydrosystem studied , called ``Ile de Camargue", is the central part of the…”
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